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The map label for this gene is rpiA [H]

Identifier: 218928088

GI number: 218928088

Start: 1004710

End: 1005366

Strand: Reverse

Name: rpiA [H]

Synonym: YPO0915

Alternate gene names: 218928088

Gene position: 1005366-1004710 (Counterclockwise)

Preceding gene: 218928090

Following gene: 218928087

Centisome position: 21.6

GC content: 47.95

Gene sequence:

>657_bases
ATGACTCAGGATGAACTTAAAAAAGCGGTGGGCTGGGCAGCATTAGATTACGTTAAACCCGGTACGATTGTGGGTGTCGG
CACGGGTTCAACTGCGGCGCATTTTATTGACGCGCTAGGCTCGATTAAACATCAGATCGAAGGGGCTGTTTCCAGTTCTG
ATGCTTCAACCGCCAAGCTGAAAAGCTATGGTATCCCAGTATTTGATTGTAATGACGTTGATGTATTGGATATCTATGTT
GATGGTGCTGACGAAATTAACGGCCAAATGCAGATGATTAAAGGCGGTGGCGCAGCACTGACCCGAGAGAAGATTATTGC
GGCTATCGCCCGGAAGTTTATCTGTATTGCTGATGAATCCAAACAAGTTGGTGTGCTGGGTAAATTCCCCCTGCCAGTCG
AAGTGATCCCGATGGCCCGCTCTTATGTGGCGCGTGAGCTGATTAAATTGGGTGGTTTGCCTGAATACCGTCAGAATGTC
CTGACCGATAACGGTAACGTTATTCTGGATGTCCACAACTTGAGTATTTTGGATGCTATCGCTTTAGAGAACCAAATTAA
TGGCATTGCCGGTGTCGTAACGGTGGGGCTATTTGCGAATCGCGGTGCTGATGTGGCCCTGATTGGTACGGCCAATGGCG
TTAAAGTGATTGGCTAA

Upstream 100 bases:

>100_bases
TAGAATTAACCCTGTCATAAACGGGCTTTATTGAGACGATTTTTGCTGTGCATGTTCTATAATAAGCTTTTGTTTTCATA
TCATAGGCAGTGAACTTACC

Downstream 100 bases:

>100_bases
AATTTTTCAGGGTGTCGTTTATTTGGCTTCACCCTGATAATTTTTTGCCTTTGAATATCTTTTCTTAAAACCATTGAATT
TGGTGATATATATCACATTC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKLKSYGIPVFDCNDVDVLDIYV
DGADEINGQMQMIKGGGAALTREKIIAAIARKFICIADESKQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYRQNV
LTDNGNVILDVHNLSILDAIALENQINGIAGVVTVGLFANRGADVALIGTANGVKVIG

Sequences:

>Translated_218_residues
MTQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKLKSYGIPVFDCNDVDVLDIYV
DGADEINGQMQMIKGGGAALTREKIIAAIARKFICIADESKQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYRQNV
LTDNGNVILDVHNLSILDAIALENQINGIAGVVTVGLFANRGADVALIGTANGVKVIG
>Mature_217_residues
TQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKLKSYGIPVFDCNDVDVLDIYVD
GADEINGQMQMIKGGGAALTREKIIAAIARKFICIADESKQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYRQNVL
TDNGNVILDVHNLSILDAIALENQINGIAGVVTVGLFANRGADVALIGTANGVKVIG

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=211, Percent_Identity=36.4928909952607, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=83.4101382488479, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=36.6666666666667, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=235, Percent_Identity=28.0851063829787, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 22802; Mature: 22670

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKL
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
KSYGIPVFDCNDVDVLDIYVDGADEINGQMQMIKGGGAALTREKIIAAIARKFICIADES
HHCCCCEEECCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEECCC
KQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYRQNVLTDNGNVILDVHNLSILDAI
CCCCEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCHHHHHH
ALENQINGIAGVVTVGLFANRGADVALIGTANGVKVIG
HHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKL
CHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
KSYGIPVFDCNDVDVLDIYVDGADEINGQMQMIKGGGAALTREKIIAAIARKFICIADES
HHCCCCEEECCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEECCC
KQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYRQNVLTDNGNVILDVHNLSILDAI
CCCCEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCHHHHHH
ALENQINGIAGVVTVGLFANRGADVALIGTANGVKVIG
HHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA