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The map label for this gene is agaR [H]

Identifier: 218928007

GI number: 218928007

Start: 911375

End: 912151

Strand: Direct

Name: agaR [H]

Synonym: YPO0831

Alternate gene names: 218928007

Gene position: 911375-912151 (Clockwise)

Preceding gene: 218928003

Following gene: 218928008

Centisome position: 19.58

GC content: 47.88

Gene sequence:

>777_bases
GTGAAAGCGGCAATCGAAAGGCGCATGGAAATCTTCAATATAGTAACCCAGCAAGGGAAAGCTCGTGTCGAAGATCTAGC
CGAAAGATTCAATGTCTCAAGTGTCACCATTCGTAGTGACCTGAGTTTTTTAGAGAAAAACGGGTACATCGTCAGATCGC
ACGGTTCGGCTATTCCGAACACCGGCGTTATCGCCGAGCTGACTGTCCATGAAAAGCGGCGCCGTAATTCCGGCGTGAAA
TCGCTGATTGGTCAGGCGGCGGCGAAGCTGATTAACAGTGGTGACACCGTCATTCTGGATTCAGGGACAACCACACGGGA
AATTGCGGCCAACTTGAGGTCGGTAGAGAACGTAGTGGTTATGACGAATGGTCTTGATGTGGCTATGGAGTTAGCATCCG
CTCCCGGCGTGGAAGTCCTCATCTCCGGTGGTGTGTTGCGTAAGAGTGCGATGTCTTTTTCTGGTTCTCAAGCCGAAGCC
AGCCTGAAAAACTTTCGTTTTGACAAAGTTTTTCTGGGTGTTGATGGTTTTGACTTGCGAGTTGGTATCACCACATATAA
TGAGCAGGAAGCGAGTCTTAACCGCCTAATGTGTGACATCTCGGAACAAATTATTGCCGTTGCTGATTCGACCAAGTTTG
GGAAACGCAGCTGCCACATGATTCGAGAGTTTGGTGATATCGATATTTTGGTGACGGATTCGGATATTCCTGAAGAGTAT
GTGCAGCGACTACGGGATATGCGAATTGAAGTGATCATAGCTGAAAAAGAGAAATAA

Upstream 100 bases:

>100_bases
CATAAGTTTTGATCTTTCTCATTGAAGATAAACGTAAGCGTAGTAATCTTAATTCGAAGCCAAACGAATAAAATTCGACT
GGTTTCGTAAGGGGACAGAA

Downstream 100 bases:

>100_bases
CACCTTGACTCCATAGTGACATTATTAATGTTAATTGTGGAGTTAATGTATGCATCCTTTAGAAAAACTGGTTCAGCGCC
ATAAAGCCGGGGAACAAATT

Product: DeoR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKAAIERRMEIFNIVTQQGKARVEDLAERFNVSSVTIRSDLSFLEKNGYIVRSHGSAIPNTGVIAELTVHEKRRRNSGVK
SLIGQAAAKLINSGDTVILDSGTTTREIAANLRSVENVVVMTNGLDVAMELASAPGVEVLISGGVLRKSAMSFSGSQAEA
SLKNFRFDKVFLGVDGFDLRVGITTYNEQEASLNRLMCDISEQIIAVADSTKFGKRSCHMIREFGDIDILVTDSDIPEEY
VQRLRDMRIEVIIAEKEK

Sequences:

>Translated_258_residues
MKAAIERRMEIFNIVTQQGKARVEDLAERFNVSSVTIRSDLSFLEKNGYIVRSHGSAIPNTGVIAELTVHEKRRRNSGVK
SLIGQAAAKLINSGDTVILDSGTTTREIAANLRSVENVVVMTNGLDVAMELASAPGVEVLISGGVLRKSAMSFSGSQAEA
SLKNFRFDKVFLGVDGFDLRVGITTYNEQEASLNRLMCDISEQIIAVADSTKFGKRSCHMIREFGDIDILVTDSDIPEEY
VQRLRDMRIEVIIAEKEK
>Mature_258_residues
MKAAIERRMEIFNIVTQQGKARVEDLAERFNVSSVTIRSDLSFLEKNGYIVRSHGSAIPNTGVIAELTVHEKRRRNSGVK
SLIGQAAAKLINSGDTVILDSGTTTREIAANLRSVENVVVMTNGLDVAMELASAPGVEVLISGGVLRKSAMSFSGSQAEA
SLKNFRFDKVFLGVDGFDLRVGITTYNEQEASLNRLMCDISEQIIAVADSTKFGKRSCHMIREFGDIDILVTDSDIPEEY
VQRLRDMRIEVIIAEKEK

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=47.2, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=36.144578313253, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=29.9212598425197, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=29.5546558704453, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=26.984126984127, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=28.1746031746032, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=30.3030303030303, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790753, Length=243, Percent_Identity=27.9835390946502, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787063, Length=255, Percent_Identity=25.0980392156863, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=24.6808510638298, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790635, Length=255, Percent_Identity=24.7058823529412, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28401; Mature: 28401

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAIERRMEIFNIVTQQGKARVEDLAERFNVSSVTIRSDLSFLEKNGYIVRSHGSAIPN
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEEEECCCCCCC
TGVIAELTVHEKRRRNSGVKSLIGQAAAKLINSGDTVILDSGTTTREIAANLRSVENVVV
CCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCEEEE
MTNGLDVAMELASAPGVEVLISGGVLRKSAMSFSGSQAEASLKNFRFDKVFLGVDGFDLR
EECCHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCEEE
VGITTYNEQEASLNRLMCDISEQIIAVADSTKFGKRSCHMIREFGDIDILVTDSDIPEEY
EEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
VQRLRDMRIEVIIAEKEK
HHHHHCCEEEEEEEECCC
>Mature Secondary Structure
MKAAIERRMEIFNIVTQQGKARVEDLAERFNVSSVTIRSDLSFLEKNGYIVRSHGSAIPN
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEEEECCCCCCC
TGVIAELTVHEKRRRNSGVKSLIGQAAAKLINSGDTVILDSGTTTREIAANLRSVENVVV
CCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCEEEE
MTNGLDVAMELASAPGVEVLISGGVLRKSAMSFSGSQAEASLKNFRFDKVFLGVDGFDLR
EECCHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCEEE
VGITTYNEQEASLNRLMCDISEQIIAVADSTKFGKRSCHMIREFGDIDILVTDSDIPEEY
EEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
VQRLRDMRIEVIIAEKEK
HHHHHCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]