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The map label for this gene is citT [C]

Identifier: 218927942

GI number: 218927942

Start: 813844

End: 815214

Strand: Direct

Name: citT [C]

Synonym: YPO0759

Alternate gene names: 218927942

Gene position: 813844-815214 (Clockwise)

Preceding gene: 218927941

Following gene: 218927949

Centisome position: 17.49

GC content: 50.77

Gene sequence:

>1371_bases
ATGGCTGACGCACCTTTATCGACTGCTGCACCGCCCTCAATCTCCAGGCGTAATTTAGCGATTCTGATTACTGATATTCT
GCTATTTATTCTTCTACTTAACGTTCTACCTTTCGACACTAACGCCAATCGCGGCTTGGCCTTTATTGGCATCCTCTGGC
TGACCGAAGCCCTTCACGTCACGATCACCGCGCTGTTGGTTCCCCTGATCGCCGTGGGTACGGGGCTAATGGACGTTAAC
ACGGGGTTGAGATCCTTCGCTAACCCCATCATCTTTCTATTCTTTGGTGGCTTTGCTCTGGCAACGGCACTGCATATTCA
AGGTCTGGATAAACTGATTGCCAACCGCCTGCTACTTGCGGCGAAGGGGCAATTGATGGTTGCGGTGCTGATGCTGTTTG
GTGCCACGGCATTAGTGTCCATGTGGATTAGTAATACCGCGACGACGGCGATGATGCTGCCGCTGGCATTAGGTGTCATC
GGTAACCTGAACCTGGAACGAGAACGTAATACCTATGTCTTTATTCTGCTGGGTATTGCCTATAGCGCCAGTATCGGTGG
GTTGGGTACCTTGGTGGGGAGCCCGCCTAATGCCATTGCAGCGGCACAGTTGGGGTTAGATTTTGTCGGTTGGATGAAAT
ATGGCACTCCCGCCATGATCATTCTGATGCCACTAATGGTGGCGACGCTGTACGTCATTCTGCGGCCTAATCTTAAGCAT
CATTTTGATATCGAACTGGAGCAACTGCCTTGGACGGCCGCACGCAGAATCACGATAGGTATTTTCGGTATGACGGTCAT
TGGCTGGATTTTCAGCAGTCAATTGAGCCAAATGCTCGGTGGGGTGAAACAGTTTGATACGCTGGTCGCACTGAGTGCAG
TCGTCCTGATTGGCATTAGCGGCGTCGCCAGTTGGCGTCAGATTCAGCAAAATACCGGATGGGGGGTATTGCTGCTATTT
GGTGGGGGCTTGACGTTAAGTGTTATTCTGCGCGATTCCGGTGCCAGCGCCGTCATGGCACAAGGCATTGTCTCCATTTT
TGGTGCCTATCACTGGTTTATTATTATTCTGGCAGTAGCGACTTTTATCATCTTCCTAACCGAACTTACCAGTAATACAG
CCAGTGCGGCTTTGCTCGTGCCGGTGTTTGCCACTGTCTCTGAGGCGTTAGGTATGCCACCGCTTCTGCTCACCATGATC
ATTGGTATCGGTGCGTCCTGCGCATTTATGCTGCCGGTCGCCACGCCACCAAATGCCATTGTTTATGGTACGGGTTTTAT
CAGGCAACCCGAGATGGTGAAGGTTGGTTTTTGGTTAAATATCATCTGCATCATCGTTGTCTCGCTGTTAGCCTGGTATC
TCTGGTATTAA

Upstream 100 bases:

>100_bases
CCATAACGAATTGCTCATTTATTATACTAAAAAACAAACGCAACGATATAACCCCATGAGGTTCACGTGATCTAACGATA
AAAAATGAGGATACTTTGTT

Downstream 100 bases:

>100_bases
GCGCTGAACCTGGCGGTACATTACGCCGTCAGGGAATTAGGCCCCTGCATGGGCCTAATTTATGGGGCAATGACAAAAGG
CGCGCTTATCGGTGATCAGG

Product: Sodium:sulfate symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MADAPLSTAAPPSISRRNLAILITDILLFILLLNVLPFDTNANRGLAFIGILWLTEALHVTITALLVPLIAVGTGLMDVN
TGLRSFANPIIFLFFGGFALATALHIQGLDKLIANRLLLAAKGQLMVAVLMLFGATALVSMWISNTATTAMMLPLALGVI
GNLNLERERNTYVFILLGIAYSASIGGLGTLVGSPPNAIAAAQLGLDFVGWMKYGTPAMIILMPLMVATLYVILRPNLKH
HFDIELEQLPWTAARRITIGIFGMTVIGWIFSSQLSQMLGGVKQFDTLVALSAVVLIGISGVASWRQIQQNTGWGVLLLF
GGGLTLSVILRDSGASAVMAQGIVSIFGAYHWFIIILAVATFIIFLTELTSNTASAALLVPVFATVSEALGMPPLLLTMI
IGIGASCAFMLPVATPPNAIVYGTGFIRQPEMVKVGFWLNIICIIVVSLLAWYLWY

Sequences:

>Translated_456_residues
MADAPLSTAAPPSISRRNLAILITDILLFILLLNVLPFDTNANRGLAFIGILWLTEALHVTITALLVPLIAVGTGLMDVN
TGLRSFANPIIFLFFGGFALATALHIQGLDKLIANRLLLAAKGQLMVAVLMLFGATALVSMWISNTATTAMMLPLALGVI
GNLNLERERNTYVFILLGIAYSASIGGLGTLVGSPPNAIAAAQLGLDFVGWMKYGTPAMIILMPLMVATLYVILRPNLKH
HFDIELEQLPWTAARRITIGIFGMTVIGWIFSSQLSQMLGGVKQFDTLVALSAVVLIGISGVASWRQIQQNTGWGVLLLF
GGGLTLSVILRDSGASAVMAQGIVSIFGAYHWFIIILAVATFIIFLTELTSNTASAALLVPVFATVSEALGMPPLLLTMI
IGIGASCAFMLPVATPPNAIVYGTGFIRQPEMVKVGFWLNIICIIVVSLLAWYLWY
>Mature_455_residues
ADAPLSTAAPPSISRRNLAILITDILLFILLLNVLPFDTNANRGLAFIGILWLTEALHVTITALLVPLIAVGTGLMDVNT
GLRSFANPIIFLFFGGFALATALHIQGLDKLIANRLLLAAKGQLMVAVLMLFGATALVSMWISNTATTAMMLPLALGVIG
NLNLERERNTYVFILLGIAYSASIGGLGTLVGSPPNAIAAAQLGLDFVGWMKYGTPAMIILMPLMVATLYVILRPNLKHH
FDIELEQLPWTAARRITIGIFGMTVIGWIFSSQLSQMLGGVKQFDTLVALSAVVLIGISGVASWRQIQQNTGWGVLLLFG
GGLTLSVILRDSGASAVMAQGIVSIFGAYHWFIIILAVATFIIFLTELTSNTASAALLVPVFATVSEALGMPPLLLTMII
GIGASCAFMLPVATPPNAIVYGTGFIRQPEMVKVGFWLNIICIIVVSLLAWYLWY

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=506, Percent_Identity=28.8537549407115, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI301069349, Length=332, Percent_Identity=28.0120481927711, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI19923838, Length=346, Percent_Identity=26.3005780346821, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4506979, Length=152, Percent_Identity=36.1842105263158, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI225637552, Length=152, Percent_Identity=36.1842105263158, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI225637549, Length=152, Percent_Identity=36.1842105263158, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI301069353, Length=146, Percent_Identity=33.5616438356164, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI31377715, Length=146, Percent_Identity=33.5616438356164, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI58761541, Length=146, Percent_Identity=33.5616438356164, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI301069346, Length=146, Percent_Identity=33.5616438356164, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI31795546, Length=151, Percent_Identity=31.1258278145695, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI219802232, Length=443, Percent_Identity=26.410835214447, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551790, Length=508, Percent_Identity=25, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988385, Length=471, Percent_Identity=26.963906581741, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71989118, Length=500, Percent_Identity=25.6, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565804, Length=469, Percent_Identity=26.6524520255864, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564681, Length=497, Percent_Identity=23.943661971831, Blast_Score=121, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322263, Length=434, Percent_Identity=25.5760368663594, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324340, Length=426, Percent_Identity=25.1173708920188, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319885, Length=438, Percent_Identity=26.2557077625571, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45551633, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281366409, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737623, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666468, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281362116, Length=120, Percent_Identity=34.1666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362114, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362112, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 48768; Mature: 48637

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAPLSTAAPPSISRRNLAILITDILLFILLLNVLPFDTNANRGLAFIGILWLTEALHV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TITALLVPLIAVGTGLMDVNTGLRSFANPIIFLFFGGFALATALHIQGLDKLIANRLLLA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGQLMVAVLMLFGATALVSMWISNTATTAMMLPLALGVIGNLNLERERNTYVFILLGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHH
YSASIGGLGTLVGSPPNAIAAAQLGLDFVGWMKYGTPAMIILMPLMVATLYVILRPNLKH
HHCCCCCCHHHCCCCCCHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
HFDIELEQLPWTAARRITIGIFGMTVIGWIFSSQLSQMLGGVKQFDTLVALSAVVLIGIS
CCCCCHHHCCCHHHHEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GVASWRQIQQNTGWGVLLLFGGGLTLSVILRDSGASAVMAQGIVSIFGAYHWFIIILAVA
HHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFIIFLTELTSNTASAALLVPVFATVSEALGMPPLLLTMIIGIGASCAFMLPVATPPNAI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEE
VYGTGFIRQPEMVKVGFWLNIICIIVVSLLAWYLWY
EECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADAPLSTAAPPSISRRNLAILITDILLFILLLNVLPFDTNANRGLAFIGILWLTEALHV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TITALLVPLIAVGTGLMDVNTGLRSFANPIIFLFFGGFALATALHIQGLDKLIANRLLLA
HHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGQLMVAVLMLFGATALVSMWISNTATTAMMLPLALGVIGNLNLERERNTYVFILLGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHH
YSASIGGLGTLVGSPPNAIAAAQLGLDFVGWMKYGTPAMIILMPLMVATLYVILRPNLKH
HHCCCCCCHHHCCCCCCHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
HFDIELEQLPWTAARRITIGIFGMTVIGWIFSSQLSQMLGGVKQFDTLVALSAVVLIGIS
CCCCCHHHCCCHHHHEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GVASWRQIQQNTGWGVLLLFGGGLTLSVILRDSGASAVMAQGIVSIFGAYHWFIIILAVA
HHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFIIFLTELTSNTASAALLVPVFATVSEALGMPPLLLTMIIGIGASCAFMLPVATPPNAI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEE
VYGTGFIRQPEMVKVGFWLNIICIIVVSLLAWYLWY
EECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]