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The map label for this gene is insK [H]

Identifier: 218927940

GI number: 218927940

Start: 810411

End: 811196

Strand: Direct

Name: insK [H]

Synonym: YPO0756

Alternate gene names: 218927940

Gene position: 810411-811196 (Clockwise)

Preceding gene: 218927939

Following gene: 218927941

Centisome position: 17.41

GC content: 46.44

Gene sequence:

>786_bases
TTGGCACGCAGTACATACTATTATCATGCATCGAAACCGGACGGTGTAATTGATGACTATGCAGATGCGGTAAAAGCGAT
TGGCGCCCTAAGCAGACGACACGCACAGCGCTACGGTTATCGCCGGATGACGGTCGCACTGAGAAAAGAAGGGTTCACAC
TGAATCACAAAACGGTGCGAAAACTGATGAATCAGCACGGGTTACTCAGCCTCATTCGGCGGAAAAAATATCGCTCCTAT
AGGGCCGATGGTGGCCGGGCATCCGATAATCTATTGGCTCGTAATTTTACATCCGAAATCAGTGGATTGAAGTGGTGTAC
AGATGTCACAGAGTTCCGAGTTGGAGCACAGAAGCTGTATTTGTCGGTGATACAAGACCTGTTTAATAATGAGATTATTT
CTTGGCATATGTCAGAAAGAGCAGCATTAATCCTGACGTGCAAGACGCTGGAAAAAGCGCTGAAAGTGAAAGGGAGAAAA
GAAGGCCTGATGTTGCACAGCGATCAGGGCTGGCATTACCGAACGCCGATGTGGCGCTCAATGCTTGTCGAGGCGGGGAT
AAGGCAAAGTATGTCACGCAAAGGCAATTGTTTAGATAATGCAGTGATGGAAAATTTCTTCAGTCACCTGAAAGCCGAGA
TGTATCACCGTAAGAAGTACGATTCAGCCACAGTTTTAAAGCGTGACATTGTAGAATATATCCATTATTACAATACAGAG
CGCATTAGCCTGAAAACAGGCGGAATGAGTCCGGCAGAATACCGGACTCAGGTAGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
TGAGAGAAGAAAAGGCACTCAGGGAGCAGCAGAAAAAACCAGAATAGTTCAAGCACTGACAGCAGAACATCGACTTTCTT
GCCTACTGTGTGCCGCAAAA

Downstream 100 bases:

>100_bases
AGCAGATGTCCAAGTTTTGGGGTTCAGTGCATAAGCGGTACCCTCCTCATTAAAAACATCATGGAACCAGCGGGACGCAT
AGTCATTATCGGTACGTTTA

Product: transposase for insertion sequence IS1661

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
RISLKTGGMSPAEYRTQVEKQ

Sequences:

>Translated_261_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
RISLKTGGMSPAEYRTQVEKQ
>Mature_260_residues
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYR
ADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKE
GLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTER
ISLKTGGMSPAEYRTQVEKQ

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=231, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1789981, Length=260, Percent_Identity=48.0769230769231, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1788405, Length=224, Percent_Identity=36.6071428571429, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1787263, Length=224, Percent_Identity=36.6071428571429, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786753, Length=224, Percent_Identity=36.6071428571429, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786570, Length=224, Percent_Identity=36.6071428571429, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786490, Length=224, Percent_Identity=36.6071428571429, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30390; Mature: 30259

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RISLKTGGMSPAEYRTQVEKQ
EEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RISLKTGGMSPAEYRTQVEKQ
EEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]