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The map label for this gene is flgH

Identifier: 218927915

GI number: 218927915

Start: 787510

End: 788175

Strand: Direct

Name: flgH

Synonym: YPO0729

Alternate gene names: 218927915

Gene position: 787510-788175 (Clockwise)

Preceding gene: 218927914

Following gene: 218927916

Centisome position: 16.92

GC content: 53.0

Gene sequence:

>666_bases
ATGAAAAGGTTTTTAATACTGACGCCAATGGTGCTGGCGTTGTGTGGCTGTGAAAGCCCCGCGCTGTTGGTACAAAAAGA
TGATGCCGAATTTGCGCCACCGGCCAATCTGATTCAACCCGCGACGGTAACGGAAGGAGGGGGGCTGTTTCAGCCCGCTA
ACAGCTGGTCGCTGTTGCAGGATCGCCGTGCGTACCGGATCGGCGATATTTTGACCGTGATACTGGATGAATCCACTCAA
TCCAGCAAGCAGGCCAAAACCAACTTTGGCAAAAAGAATGACATGAGCTTGGGGGTACCGGAAGTCTTGGGCAAAAAACT
GAATAAATTTGGCGGCTCCATCTCCGGTAAGCGCGATTTTGACGGCAGTGCCACCTCAGCACAGCAAAATATGCTGCGTG
GATCGATAACCGTTGCGGTCCATCAGGTATTGCCTAACGGCGTCTTGGTGATCCGTGGCGAAAAATGGCTGACCCTCAAC
CAAGGCGATGAATATATGCGGGTCACGGGTTTAGTGCGGGCAGATGATGTGGCACGGGATAACTCGGTTTCTTCTCAGCG
CATCGCCAACGCCCGTATCTCCTATGCCGGTCGTGGTGCGCTCAGTGATGCTAACTCAGCCGGTTGGTTAACGCGCTTCT
TCAACCATCCGCTATTCCCAATTTAG

Upstream 100 bases:

>100_bases
GAGATGAACGCCAAAATGGTCTCTGCCGCCGATGACATGCTGAAATTTGTTAGCCAGAAGCTGTGATCGCCAGCACCCTC
TTTTGAAAAGTGAATGACGA

Downstream 100 bases:

>100_bases
GCAGGAGCTTGATATGTTTTTAAACCGGATACATTTTTCGGCCCTGATGCGGTTTTTTTCGGTCTCGATAAGGTTCTTGT
CGGTCTTGATAAAAACGAGG

Product: flagellar basal body L-ring protein

Products: NA

Alternate protein names: Basal body L-ring protein 1

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKRFLILTPMVLALCGCESPALLVQKDDAEFAPPANLIQPATVTEGGGLFQPANSWSLLQDRRAYRIGDILTVILDESTQ
SSKQAKTNFGKKNDMSLGVPEVLGKKLNKFGGSISGKRDFDGSATSAQQNMLRGSITVAVHQVLPNGVLVIRGEKWLTLN
QGDEYMRVTGLVRADDVARDNSVSSQRIANARISYAGRGALSDANSAGWLTRFFNHPLFPI

Sequences:

>Translated_221_residues
MKRFLILTPMVLALCGCESPALLVQKDDAEFAPPANLIQPATVTEGGGLFQPANSWSLLQDRRAYRIGDILTVILDESTQ
SSKQAKTNFGKKNDMSLGVPEVLGKKLNKFGGSISGKRDFDGSATSAQQNMLRGSITVAVHQVLPNGVLVIRGEKWLTLN
QGDEYMRVTGLVRADDVARDNSVSSQRIANARISYAGRGALSDANSAGWLTRFFNHPLFPI
>Mature_221_residues
MKRFLILTPMVLALCGCESPALLVQKDDAEFAPPANLIQPATVTEGGGLFQPANSWSLLQDRRAYRIGDILTVILDESTQ
SSKQAKTNFGKKNDMSLGVPEVLGKKLNKFGGSISGKRDFDGSATSAQQNMLRGSITVAVHQVLPNGVLVIRGEKWLTLN
QGDEYMRVTGLVRADDVARDNSVSSQRIANARISYAGRGALSDANSAGWLTRFFNHPLFPI

Specific function: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation

COG id: COG2063

COG function: function code N; Flagellar basal body L-ring protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable). Bacterial flagellum basal body

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgH family

Homologues:

Organism=Escherichia coli, GI1787319, Length=226, Percent_Identity=33.6283185840708, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLGH1_YERPE (Q8ZHZ5)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AI0089
- RefSeq:   NP_670747.1
- RefSeq:   NP_994338.1
- RefSeq:   YP_002345790.1
- ProteinModelPortal:   Q8ZHZ5
- IntAct:   Q8ZHZ5
- GeneID:   1148396
- GeneID:   1173570
- GeneID:   2764315
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO0729
- KEGG:   ypk:y3449
- KEGG:   ypm:YP_3040
- HOGENOM:   HBG507455
- OMA:   CESQAIL
- ProtClustDB:   PRK12407
- BioCyc:   YPES187410:Y3449-MONOMER
- BioCyc:   YPES214092:YPO0729-MONOMER
- HAMAP:   MF_00415
- InterPro:   IPR000527
- PRINTS:   PR01008

Pfam domain/function: PF02107 FlgH

EC number: NA

Molecular weight: Translated: 23964; Mature: 23964

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLILTPMVLALCGCESPALLVQKDDAEFAPPANLIQPATVTEGGGLFQPANSWSLLQ
CCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHH
DRRAYRIGDILTVILDESTQSSKQAKTNFGKKNDMSLGVPEVLGKKLNKFGGSISGKRDF
HHHHHHHHHEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DGSATSAQQNMLRGSITVAVHQVLPNGVLVIRGEKWLTLNQGDEYMRVTGLVRADDVARD
CCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCEEEEECCCCCEEEEEEEEECCCCCCC
NSVSSQRIANARISYAGRGALSDANSAGWLTRFFNHPLFPI
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRFLILTPMVLALCGCESPALLVQKDDAEFAPPANLIQPATVTEGGGLFQPANSWSLLQ
CCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHH
DRRAYRIGDILTVILDESTQSSKQAKTNFGKKNDMSLGVPEVLGKKLNKFGGSISGKRDF
HHHHHHHHHEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DGSATSAQQNMLRGSITVAVHQVLPNGVLVIRGEKWLTLNQGDEYMRVTGLVRADDVARD
CCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCEEEEECCCCCEEEEEEEEECCCCCCC
NSVSSQRIANARISYAGRGALSDANSAGWLTRFFNHPLFPI
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430