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The map label for this gene is exbB [H]

Identifier: 218927873

GI number: 218927873

Start: 745023

End: 745736

Strand: Direct

Name: exbB [H]

Synonym: YPO0682

Alternate gene names: 218927873

Gene position: 745023-745736 (Clockwise)

Preceding gene: 218927870

Following gene: 218927874

Centisome position: 16.01

GC content: 51.54

Gene sequence:

>714_bases
ATGGATTTATCTGTCTGGGGTATGTATCAGAATGCGGACGTGGTTGTTAAAGGCGTCATGATTGGTCTGGTGCTGGCTTC
TATCGTCACTTGGACCATTCTGTTCTCTAAAGGGACTGAATTGTTCCGCGCTCGTCGTCGGTTGCGCCAAGAGCATGAAG
TGATTGGGGCCGTGACCGATCTTGATACCGCTTCGGAGCGAGCAGAAGATTTTGGTCAAGGCAGCGTAAGCAGTTTGTTA
CTGCATGAAGCACTGAACGAGCGCCTGTTGTCGATAGAGTCAAATGACAATAATGGCATTAAAGAACGTACTGCTTTCCG
TTTGGAGCGCCGGGTAGCCGCCATTGGCCGCCAAATGGGCAAAGGTAATGGCTTCCTGGCAACAATCGGCGCAATTTCCC
CCTTTGTCGGTTTGTTTGGTACGGTTTGGGGCATCATGAACAGCTTTATCGGCATTGCCCACTCACAGACCACCAATCTG
GCGGTTATCGCTCCAGGGATTGCCGAAGCGTTATTGGCAACGGCGTTAGGGCTGGTGGCTGCGATCCCAGCGGTCGTTAT
TTATAATATCTTTGCTCGCCAGATCGGAAATTATCGCGCTCAAGTGGGTGATGTCGCGGCACAAGTGTTACTGCTGTTGA
GCCGTGATTTGGATTTGGCCAGTAGCGCCGAAGTAAAGTCCCCTCGCCATCCTCATCAATTACGAGCAGGGTGA

Upstream 100 bases:

>100_bases
ACCAGAGTCAGTATTAACATCAGCATCAGCATTAACCTCAGAATCAATACCGGCCCCTATGGTTCAGCCCGTTACGGCTC
CAGTACCACAAAAGCTGGCG

Downstream 100 bases:

>100_bases
TTTATGGCAATGCGAATGAATGATTCCCTCGACGAGAGTGGAGAATTACACGAAATTAACGTGACGCCGTTTATTGATGT
CATGTTGGTGCTGCTGATTA

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLL
LHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNL
AVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG

Sequences:

>Translated_237_residues
MDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLL
LHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNL
AVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
>Mature_237_residues
MDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLL
LHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNL
AVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=236, Percent_Identity=70.7627118644068, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI1786958, Length=235, Percent_Identity=31.4893617021277, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25503; Mature: 25503

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTD
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
LDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KGNGFLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHH
AIPAVVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTD
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
LDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
KGNGFLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHH
AIPAVVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]