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The map label for this gene is ribB [H]

Identifier: 218927851

GI number: 218927851

Start: 718102

End: 718755

Strand: Direct

Name: ribB [H]

Synonym: YPO0658

Alternate gene names: 218927851

Gene position: 718102-718755 (Clockwise)

Preceding gene: 218927850

Following gene: 218927852

Centisome position: 15.43

GC content: 52.45

Gene sequence:

>654_bases
ATGAATCAGACGCTTCTCTCAGATTTTGGCACGCCTGTCGAGCGTGTAGAACGTGCAATCGACGCCCTGCGTAATGGCCG
TGGCGTTATGGTGTTGGATGACGAAAGTCGTGAAAACGAAGGCGATATGGTTTTTGCTGCCGAAGCAATGACGCTAGAGC
AAATGGCTCTGACCATCCGCCACGGTAGTGGCATTGTCTGTCTGTGTATCACTGATGAACGCCGCCAGCAGCTTGATTTA
CCCATGATGGTTACCCATAACTCCAGCCAATTCCAGACAGCGTTTACCGTGACAATTGAAGCGGCGGAAGGTGTGACGAC
TGGGGTTTCTGCGGCTGACCGTCTGACCACTATCCGTAAGGCAATCGCTGATAACGCTAAACCTGCTGATCTTAATCGGC
CGGGGCATGTATTCCCGCTGCGTGGTCAACCTGGTGGCGTATTATCACGCCGTGGTCATACCGAAGCGTCTATCGATTTG
GCGACACTGGCAGGTTACAAACCGGCTGGTGTGCTGTGTGAACTGACCAATGACGACGGTAGCATGGCTCATGCTCCAGA
AGTGATTGCGTTTGCTAAATTGCATGATATGCCCGTCGTGACGATTGACGATTTGGCGGCTTATCTCCAATCTCGCGCGA
AGAAAGCCAGCTAA

Upstream 100 bases:

>100_bases
GGTCCGCTTGCGTTATTTCGGCTATTTATTTTTGGCCTTTTACTCCTCAAGACCGCCCTGATTCTGGTAATCCATAATTT
TTTAATGAGGTTTCTTTACC

Downstream 100 bases:

>100_bases
TCTGATGGCGATCTCGCCTGATATTATTTGGTGATATCGCTGGCTGGTTAATATCATAGGCTTGTTAATATTGCTGGCTG
GTTAGTGTGGCTGCCTTATT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDL
PMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDL
ATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS

Sequences:

>Translated_217_residues
MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDL
PMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDL
ATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
>Mature_217_residues
MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDL
PMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDL
ATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=217, Percent_Identity=77.4193548387097, Blast_Score=352, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=42.8571428571429, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23360; Mature: 23360

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIR
CCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHEEEEE
HGSGIVCLCITDERRQQLDLPMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRK
CCCCEEEEEEECCHHHHCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
AIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDG
HHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEHHCCCCCCCEEEEEECCCC
SMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
CCCCCCHHHEEEHHCCCCEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIR
CCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHEEEEE
HGSGIVCLCITDERRQQLDLPMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRK
CCCCEEEEEEECCHHHHCCCCEEEECCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
AIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDG
HHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEHHCCCCCCCEEEEEECCCC
SMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
CCCCCCHHHEEEHHCCCCEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA