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The map label for this gene is gcp [H]

Identifier: 218927839

GI number: 218927839

Start: 703713

End: 704726

Strand: Direct

Name: gcp [H]

Synonym: YPO0646

Alternate gene names: 218927839

Gene position: 703713-704726 (Clockwise)

Preceding gene: 218927835

Following gene: 218927841

Centisome position: 15.12

GC content: 51.87

Gene sequence:

>1014_bases
ATGCGAGTATTGGGTATAGAAACGTCCTGCGATGAAACCGGAATTGCAGTCTATGACGATAAAGCCGGTCTGTTAGCTAA
CCAATTGTACAGTCAGGTAAAATTACACGCTGACTACGGTGGTGTCGTACCTGAACTGGCCTCCCGTGATCACGTGCGTA
AGACCGTACCCCTGATTCAGGCGGCGTTGAAAGAAGCCAATTTGAGCGCCAAAGATATCGATGCGGTGGCTTATACAGCA
GGCCCTGGTTTGGTGGGGGCGTTGTTAGTGGGGGCGACCATTGGTCGGGCATTAGCTTTCGCATGGGGAGTCCCTGCGGT
ACCGGTTCATCATATGGAAGGCCATTTGTTGGCACCAATGCTGGAAGAAAATGCACCAGAGTTCCCGTTTGTTGCGCTGC
TGGTATCCGGCGGCCATACCCAATTGATTAGTGTGACCGGTATTGGTGAATATTTGCTGTTGGGCGAATCTGTTGATGAT
GCGGCAGGCGAGGCCTTTGATAAGACAGCAAAACTACTAGGGCTGGATTACCCCGGTGGGCCAATGTTGTCGCGTATGGC
TCAACAAGGTACTGTGGGGCGTTTTACCTTTCCGCGCCCAATGACTGATCGCCCTGGGCTGGATTTTAGTTTTTCCGGCC
TGAAAACGTTCGCGGCGAATACTATTCGTGCTAATGGTGATGATGACCAAACCCGTGCCGATATCGCCCGAGCATTCGAA
GATGCGGTGGTTGATACGTTGGCGATCAAGTCTAAACGTGCATTAGATCAGACGGGTTTTAAACGCTTAGTCATTGCCGG
GGGCGTGAGCGCTAACCAGACACTGCGATTAAAACTGGCCGATATGATGCAAAAACGAGGCGGTGAAGTATTCTATGCCC
GACCCGAATTTTGCACTGACAATGGCGCGATGATTGCCTATGCCGGGATGGTCAGGTTGCGAAGTAACCTGAACAGTGAG
TTGAGTGTGTCGGTGCGGCCGCGGTGGCCGTTATCTGAGTTACCAAAAGTCTGA

Upstream 100 bases:

>100_bases
CGAAAATATTGCCTTTCCCCGCGAAGGTGGGGATTAGAAATCATGACTGCGGGCGCTGTTATGCTAAACTGTCGGCCGCA
CGTGAATGATGGGAAATGTA

Downstream 100 bases:

>100_bases
TCAGAATGGCTGAGCGTGGCTGCGGCTGCGTTGCCGCAGTCATTCTGATATGGGTGTCGAATGGCTGAGCGTGGCTGCGG
CTGTGTTGCCGCAGTCATTC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTA
GPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDD
AAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFE
DAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSE
LSVSVRPRWPLSELPKV

Sequences:

>Translated_337_residues
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTA
GPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDD
AAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFE
DAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSE
LSVSVRPRWPLSELPKV
>Mature_337_residues
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTA
GPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDD
AAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFE
DAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSE
LSVSVRPRWPLSELPKV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=34.5505617977528, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI8923380, Length=338, Percent_Identity=34.6153846153846, Blast_Score=152, Evalue=3e-37,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=88.0597014925373, Blast_Score=613, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI17557464, Length=344, Percent_Identity=32.2674418604651, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=34.0557275541796, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=32.8840970350404, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322891, Length=346, Percent_Identity=28.3236994219653, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=34.7058823529412, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI21357207, Length=324, Percent_Identity=30.8641975308642, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36042; Mature: 36042

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
AALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPM
HHHHHCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEECHH
LEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGG
HHCCCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFE
HHHHHHHHCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHCEEECCCCCHHHHHHHHHHHH
DAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHCCCEEEEECCCEECC
NGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
CCCEEEHHHHHHHHHCCCCEEEEEECCCCCHHHCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
AALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPM
HHHHHCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEECHH
LEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGG
HHCCCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFE
HHHHHHHHCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHCEEECCCCCHHHHHHHHHHHH
DAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHCCCEEEEECCCEECC
NGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
CCCEEEHHHHHHHHHCCCCEEEEEECCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA