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The map label for this gene is ftsA [H]

Identifier: 218927755

GI number: 218927755

Start: 604545

End: 605801

Strand: Direct

Name: ftsA [H]

Synonym: YPO0559

Alternate gene names: 218927755

Gene position: 604545-605801 (Clockwise)

Preceding gene: 218927754

Following gene: 218927756

Centisome position: 12.99

GC content: 48.93

Gene sequence:

>1257_bases
ATGATCAAGTCGACGGACAGAAAACTGGTAGTAGGTCTCGAGATCGGAACGGCAAAGGTCTCCGCATTGGTAGGGGAAGT
TCTGCCTGATGGCATGGTCAATATTATTGGGGTAGGCAGTTGCCCATCCCGTGGCATGGATAAAGGGGGCGTTAACGACC
TTGAATCGGTAGTGAAATGCGTTCAGCGTGCTATCGATCAAGCGGAGTTAATGGCGGATTGCCAAATTTCCTCTGTTTAT
CTGGCATTATCGGGTAAACATATCAGTTGCCAGAATGAGATAGGGATGGTTCCTATTTCAGAAGAAGAAGTTACTCAGGA
AGATGTTGAGAACGTAGTGCATACCGCGAAGTCAGTACGTGTGCGTGATGAACATCGTATCCTGCACGTTATACCGCAGG
AATATGCCATCGATTATCAGGAAGGCATCAAGAATCCTGTTGGGCTTTCTGGCGTGCGGATGCAAGCCAAAGTGCACCTG
ATTACCTGCCATAACGATATGGCAAAAAATATTGTTAAAGCGGTGGAACGTTGTGGCCTAAAAGTGGACCAACTTATCTT
TGCTGGTTTAGCAGCAAGTTATGCCGTTTTGACCGAAGATGAGCGTGAACTGGGGGTCTGTGTTGTCGACATCGGCGGTG
GCACCATGGATATGGCGGTTTATACCGGTGGGGCATTACGGCACACCAAAGTGATCCCCTACGCCGGGAACGTGGTAACC
AGTGATATTGCTTATGCTTTCGGGACACCGCCAACAGATGCGGAAGCGATTAAAGTTCGGCACGGCTGTGCGCTCGGGTC
GATAGTCAGCAAGGACGAAAGTGTTGAAGTGCCAAGTGTTGGCGGACGCCCTCCTCGTAGTTTGCAAAGACAAACACTCG
CTGAGGTTATTGAACCACGCTACACCGAATTGCTGAATTTAGTTAATGACGAGATTTTACAACTGCAGGAGCAATTACGT
CAGCAAGGCGTAAAGCACCATCTGGCGGCAGGTATTGTGCTAACCGGTGGCGCTGCACAAATTGATGGTTTAGCGGAATG
TGCACAACGGGTGTTCCATGCCCAGGTCCGAATTGGTCAGCCGCTTAATATCACCGGGCTGACGGATTATGCGCAGGAGC
CTTATTACTCCACGGCTGTTGGGTTATTGCATTACGGTAAAGAATCTCATCTCAGTGGTGAGTCAGAAGTAGAAAAACGT
GCCTCAGTGGGCAATTGGTTCAAACGTATCAATAGCTGGCTGAGAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
GTTGGGCACCGGTCTTTATCGACAATCAGGGTGGAGAACCACCGATTAATGGCCAGCAGAACAGTAATCCGTAACAAAAT
CAGGCACAGGCAAAACAACA

Downstream 100 bases:

>100_bases
TGTTTCAACAAAGAGATCAAGCTGAACTTATTTTTTGATCTCGAAGCGACAGGCACAAAACGGAGAGAAACTATGTTTGA
ACCTATGGAACTAACCAATG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIKSTDRKLVVGLEIGTAKVSALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRILHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYAVLTEDERELGVCVVDIGGGTMDMAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPTDAEAIKVRHGCALGSIVSKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNDEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIDGLAECAQRVFHAQVRIGQPLNITGLTDYAQEPYYSTAVGLLHYGKESHLSGESEVEKR
ASVGNWFKRINSWLRKEF

Sequences:

>Translated_418_residues
MIKSTDRKLVVGLEIGTAKVSALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRILHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYAVLTEDERELGVCVVDIGGGTMDMAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPTDAEAIKVRHGCALGSIVSKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNDEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIDGLAECAQRVFHAQVRIGQPLNITGLTDYAQEPYYSTAVGLLHYGKESHLSGESEVEKR
ASVGNWFKRINSWLRKEF
>Mature_418_residues
MIKSTDRKLVVGLEIGTAKVSALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRILHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYAVLTEDERELGVCVVDIGGGTMDMAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPTDAEAIKVRHGCALGSIVSKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNDEILQLQEQLR
QQGVKHHLAAGIVLTGGAAQIDGLAECAQRVFHAQVRIGQPLNITGLTDYAQEPYYSTAVGLLHYGKESHLSGESEVEKR
ASVGNWFKRINSWLRKEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=95, Blast_Score=820, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45313; Mature: 45313

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSTDRKLVVGLEIGTAKVSALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKC
CCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVR
HHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
VRDEHRILHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGL
ECCCCCEEEECCHHHCCCHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVDQLIFAGLAASYAVLTEDERELGVCVVDIGGGTMDMAVYTGGALRHTKVIPYAGNVVT
CHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCEEEEEEECCCCEEEEEECCCCCCCHH
SDIAYAFGTPPTDAEAIKVRHGCALGSIVSKDESVEVPSVGGRPPRSLQRQTLAEVIEPR
HHHHHHCCCCCCCHHHEEEHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHH
YTELLNLVNDEILQLQEQLRQQGVKHHLAAGIVLTGGAAQIDGLAECAQRVFHAQVRIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHCCC
PLNITGLTDYAQEPYYSTAVGLLHYGKESHLSGESEVEKRASVGNWFKRINSWLRKEF
CCEECCCCHHHCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKSTDRKLVVGLEIGTAKVSALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKC
CCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
VQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVR
HHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCE
VRDEHRILHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGL
ECCCCCEEEECCHHHCCCHHHHCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHCCC
KVDQLIFAGLAASYAVLTEDERELGVCVVDIGGGTMDMAVYTGGALRHTKVIPYAGNVVT
CHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCEEEEEEECCCCEEEEEECCCCCCCHH
SDIAYAFGTPPTDAEAIKVRHGCALGSIVSKDESVEVPSVGGRPPRSLQRQTLAEVIEPR
HHHHHHCCCCCCCHHHEEEHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHH
YTELLNLVNDEILQLQEQLRQQGVKHHLAAGIVLTGGAAQIDGLAECAQRVFHAQVRIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHCCC
PLNITGLTDYAQEPYYSTAVGLLHYGKESHLSGESEVEKRASVGNWFKRINSWLRKEF
CCEECCCCHHHCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]