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The map label for this gene is ydiD [C]

Identifier: 218927734

GI number: 218927734

Start: 581752

End: 583557

Strand: Direct

Name: ydiD [C]

Synonym: YPO0537

Alternate gene names: 218927734

Gene position: 581752-583557 (Clockwise)

Preceding gene: 218927733

Following gene: 218927735

Centisome position: 12.5

GC content: 48.56

Gene sequence:

>1806_bases
ATGATTCATAAATTACATCAATATCACCTGGTACGTAGGTTGCGTCAGCAAGTCAGTGACCGTTCAGAGCTGGTAGCCTT
TCGTGAATGGTCACCAGAGGGTGAAAAGCAGCTCAACTGGCAGCAAATTGACGAGCATGTCACTCGGATTTCTACTGCAT
TGCTCTCTTTGGGGGCTGCAATACAAGAGCGCATTGGCATCTTTGCTAATAACAGTATGGCGTGGTCACTTGTCGATCTG
GCTATTTTACAGTTACGTGGCGTTAGTGTCCCCTTGTATGCCACCAATACCGCCGCTCAGGCAGCCTATATCGTCAATGA
TGCTGATGTGCGGATTTTGTTTGTCGGTGAGCAATCCCAATTTGATATTGCCATCACGCTGCAACCTCTCTGCCCGCAAC
TGGCTCATATCATCGTCTTGGATCCTGCGGTGGACTTACGTGGCTGTGAGTACGCCCAGCATTTGGCTGACTTTGAGCAG
CAACAGCAACCCGATACCGTACAACAGCACCTGTTAACTACGCGCATTGAAGGCTGTGATTTAGACGATCTGTTTACGCT
AATTTATACGTCGGGTACCACGGGGGAGCCAAAAGGCGTGATGTTGGATTACCGTAATATGGCAGCTCAACTCTATTTGC
ATGACCAGCGGTTAACCCTCACACCACAAGATGTGTCCCTCAGTTTTTTGCCGTTATCTCATGTTTTTGAAAGAGCCTGG
AGTTTCTATGTGATGCATACCGGTGCTCAGAACGTCTATATCCGTAATACGGATTGGGTGCGCTCTGCTATGCAGGCAGT
AAAACCAACGGTGATGTGCGCGGTGCCTCGCTTCTACGAGAAAGTATTCAGCGCGATTAATGACAAAGTCGCCTTGGCAA
AGTGGCATCAACGCGTGCTATTCCACTGGGCAGTGGGGTGCGGTGAACGTAAATTCAAACGGTTGCAGCAGGGGCGGCCA
TTACCTTGGCTCTCAGAGCAGATGTACACACTGGCAGACCGTTTGGTATTGCGCAAATTACGCGGTGTGTTAGGGGGGCG
GGTACGTTTTCTGCCCGCGGCTGGCGCACGGTTAGATGATAATATCATTCTGTTTTTCCAGGCGATTGGGGTCAATATTA
AATACGGCTATGGCATGACTGAAACCTGTGCCACGGTTTCTTGTTGGGAAGAGCAAAACTTCCGCTTTGGTTCTATCGGC
AAGCCCTTACCGGGTATTGATGTTCGCTTAGGGGCAGAGAATGAAATTCAGGTGCGTGGGCCTATCGTGATGCGTGGCTA
TTTCAAAAAGCCACAAGAGACGCTAGAAGCCTTTACCGAAGACGGATGGCTTAAGACGGGGGATGCGGGTGCTCTGGATG
CTCAGGGTCATCTGTTTATTACCGAACGTCTGAAAGACCTGATGAAAACGTCGGGGGGGAAATATATTGCCCCACAAATG
ATCGAAGGCACACTCGGACAGGATCGTTTTATTGAGCAGGTAGCGATTATTGCGGATACCCGCAAATTTGTATCAGCGTT
GATTGTCCCGAGTTTTGAATCGCTGGAAGAGTATGCCCGATCCATCAACTTGAAATATCACGATCGGTTGGAGCTATTGC
GCCATAGCCACATTGTTAACATGTTTGAGCAACGGCTGAAAGAGATACAAAAAGAGCTGGCTCTGTTTGAGCAAGTAAAA
AAGTTTACGCTGTTGCCTCAGGCGTTCACTATGGAAACCGGTGAGTTAACGCCTACGATGAAGTTGCGGCGGAAAATCAT
TCTTCAACGCTATCAGAATGAAATTGACTTGATGTATAGCGATTAA

Upstream 100 bases:

>100_bases
GACTGCGCGAAAAAAAAGTGAACACCTGTACGCTGAATGTTGTCGTACAAATCTTGCAACACACTTTAATGGATATTTCA
CCAGCGAGCGGTAATTCTTT

Downstream 100 bases:

>100_bases
TTTGTTCACCATTCCTCCCCGCAGTGACCGGTGTTAAGTCTCACACTGGTCGCTGCTGTCTTTCTGACCGTTCTGCTGTG
TTTGGCCCTGACCTACCTAT

Product: putative AMP-binding enzyme family protein

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGAAIQERIGIFANNSMAWSLVDL
AILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQSQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQ
QQQPDTVQQHLLTTRIEGCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVFERAW
SFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHQRVLFHWAVGCGERKFKRLQQGRP
LPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAAGARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIG
KPLPGIDVRLGAENEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKTSGGKYIAPQM
IEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEEYARSINLKYHDRLELLRHSHIVNMFEQRLKEIQKELALFEQVK
KFTLLPQAFTMETGELTPTMKLRRKIILQRYQNEIDLMYSD

Sequences:

>Translated_601_residues
MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGAAIQERIGIFANNSMAWSLVDL
AILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQSQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQ
QQQPDTVQQHLLTTRIEGCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVFERAW
SFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHQRVLFHWAVGCGERKFKRLQQGRP
LPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAAGARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIG
KPLPGIDVRLGAENEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKTSGGKYIAPQM
IEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEEYARSINLKYHDRLELLRHSHIVNMFEQRLKEIQKELALFEQVK
KFTLLPQAFTMETGELTPTMKLRRKIILQRYQNEIDLMYSD
>Mature_601_residues
MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGAAIQERIGIFANNSMAWSLVDL
AILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQSQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQ
QQQPDTVQQHLLTTRIEGCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVFERAW
SFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHQRVLFHWAVGCGERKFKRLQQGRP
LPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAAGARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIG
KPLPGIDVRLGAENEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKTSGGKYIAPQM
IEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEEYARSINLKYHDRLELLRHSHIVNMFEQRLKEIQKELALFEQVK
KFTLLPQAFTMETGELTPTMKLRRKIILQRYQNEIDLMYSD

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794756, Length=611, Percent_Identity=29.2962356792144, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI42794760, Length=611, Percent_Identity=29.2962356792144, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI42794758, Length=611, Percent_Identity=29.2962356792144, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI40807491, Length=617, Percent_Identity=29.3354943273906, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI57165410, Length=635, Percent_Identity=30.0787401574803, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI57165412, Length=635, Percent_Identity=30.2362204724409, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI27477105, Length=610, Percent_Identity=27.5409836065574, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI83745141, Length=599, Percent_Identity=27.3789649415693, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI42794754, Length=605, Percent_Identity=27.4380165289256, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI42794752, Length=605, Percent_Identity=27.4380165289256, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI12669909, Length=650, Percent_Identity=25.2307692307692, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4758332, Length=650, Percent_Identity=25.2307692307692, Blast_Score=182, Evalue=9e-46,
Organism=Escherichia coli, GI145693145, Length=478, Percent_Identity=25.7322175732218, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788107, Length=134, Percent_Identity=35.0746268656716, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789201, Length=152, Percent_Identity=32.2368421052632, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17510401, Length=627, Percent_Identity=27.9106858054226, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17556552, Length=588, Percent_Identity=28.2312925170068, Blast_Score=225, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17541856, Length=590, Percent_Identity=30, Blast_Score=224, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI17553312, Length=598, Percent_Identity=27.5919732441472, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI25147511, Length=607, Percent_Identity=26.3591433278418, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17564090, Length=591, Percent_Identity=24.5346869712352, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193204819, Length=617, Percent_Identity=25.2836304700162, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17558820, Length=435, Percent_Identity=25.2873563218391, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI32563687, Length=350, Percent_Identity=27.7142857142857, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559526, Length=346, Percent_Identity=28.3236994219653, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17531443, Length=340, Percent_Identity=25.5882352941176, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901848, Length=210, Percent_Identity=29.0476190476191, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=332, Percent_Identity=24.6987951807229, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324893, Length=454, Percent_Identity=28.4140969162996, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6320852, Length=617, Percent_Identity=25.2836304700162, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322182, Length=445, Percent_Identity=25.6179775280899, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323903, Length=446, Percent_Identity=26.2331838565022, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24666501, Length=611, Percent_Identity=28.8052373158756, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24666497, Length=611, Percent_Identity=28.8052373158756, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281366413, Length=611, Percent_Identity=28.8052373158756, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17933690, Length=622, Percent_Identity=25.5627009646302, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI62471689, Length=628, Percent_Identity=27.5477707006369, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI62471679, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI62471683, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI62471685, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24586636, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI62471681, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI62471687, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24586634, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI22026970, Length=628, Percent_Identity=27.5477707006369, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19921316, Length=629, Percent_Identity=25.4372019077901, Blast_Score=181, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 68753; Mature: 68753

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGAA
CCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IQERIGIFANNSMAWSLVDLAILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQSQ
HHHHHCEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCEEEEEEECCCC
FDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQQQQPDTVQQHLLTTRIEGCD
EEEEEEECHHCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVFERAW
HHHHHHHHEECCCCCCCCCEEEEHHHHEEEEEEECCEEEECCCCCCEEEECHHHHHHHHH
SFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHQRVL
EEEEEEECCCEEEEECCHHHHHHHHHHCCHHEEHHHHHHHHHHHHHCCHHHHHHHHHHHH
FHWAVGCGERKFKRLQQGRPLPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAAGARLDD
HHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
NIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIGKPLPGIDVRLGAENEIQVRG
CEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCEEEEC
PIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKTSGGKYIAPQM
CEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCEECHHH
IEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEEYARSINLKYHDRLELLRHSHIVN
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MFEQRLKEIQKELALFEQVKKFTLLPQAFTMETGELTPTMKLRRKIILQRYQNEIDLMYS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
D
C
>Mature Secondary Structure
MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGAA
CCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IQERIGIFANNSMAWSLVDLAILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQSQ
HHHHHCEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCEEEEEEECCCC
FDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQQQQPDTVQQHLLTTRIEGCD
EEEEEEECHHCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVFERAW
HHHHHHHHEECCCCCCCCCEEEEHHHHEEEEEEECCEEEECCCCCCEEEECHHHHHHHHH
SFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHQRVL
EEEEEEECCCEEEEECCHHHHHHHHHHCCHHEEHHHHHHHHHHHHHCCHHHHHHHHHHHH
FHWAVGCGERKFKRLQQGRPLPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAAGARLDD
HHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
NIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIGKPLPGIDVRLGAENEIQVRG
CEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCEEEEC
PIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKTSGGKYIAPQM
CEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCEECHHH
IEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEEYARSINLKYHDRLELLRHSHIVN
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MFEQRLKEIQKELALFEQVKKFTLLPQAFTMETGELTPTMKLRRKIILQRYQNEIDLMYS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]