Click here to switch to the map view.

The map label for this gene is mogA [H]

Identifier: 218927661

GI number: 218927661

Start: 491445

End: 492032

Strand: Direct

Name: mogA [H]

Synonym: YPO0464

Alternate gene names: 218927661

Gene position: 491445-492032 (Clockwise)

Preceding gene: 218927660

Following gene: 218927662

Centisome position: 10.56

GC content: 45.07

Gene sequence:

>588_bases
ATGAATATATTACGTATAGGTTTAGTCTCAGTTTCAGATCGGGCATCCAGTGGGATTTATCAGGATAAAGGTATTCCCGC
CTTGGAAGAGTGGCTGACGAGTGCGTTGACCACACCTTTTGAAGTCGAGACTCGTCTTATTCCCGATGAACAAAGCCTAA
TTGAACAAACACTCTGTGAATTAGTCGATGAGATGGGCTGCCATTTGGTATTGACGACAGGTGGAACTGGCCCGGCAAGG
CGTGATGTCACTCCCGATGCGACATTGGCTATTGCAGATCGGCAGATGCCAGGTTTTGGCGAGCAAATGCGTCAAATTAG
CCTGCATTATGTGCCAACCGCAATTTTATCCCGTCAGGTAGGTGTTATTCGTAAACAAGCACTTATCATCAATTTGCCGG
GGCAACCTAAATCAATTAAAGAAACCTTAGAAGGCGTTAAAGACGCTCAGTCTAACGTGGTGGTGGCTGGTATCTTCGCC
AGTGTGCCTTACTGCATTCAACTCTTAGATGGGCCTTATATAGAAACTAATACTGATGTGGTAGTGGCTTTTCGCCCAAA
AAGTGCCATTATCGATATAAAAGACTAA

Upstream 100 bases:

>100_bases
ATCGCTGAAGAGTGAATTTTGTGAACGCCAACGGTTGAGCTAATTCGGTTGCGTAGTATCATCCACTCCAGATAAAAAGG
TATTTCGTTGAGGTAATTAC

Downstream 100 bases:

>100_bases
ATAGAAAATTTCTATGACATAAGATGCCATTATGTGCGTGTGGGGAATTTTGTACGGTATAGTCATGTTAACTTTACAAA
GAGTAGAAAAATTTTTCTTC

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNILRIGLVSVSDRASSGIYQDKGIPALEEWLTSALTTPFEVETRLIPDEQSLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRQMPGFGEQMRQISLHYVPTAILSRQVGVIRKQALIINLPGQPKSIKETLEGVKDAQSNVVVAGIFA
SVPYCIQLLDGPYIETNTDVVVAFRPKSAIIDIKD

Sequences:

>Translated_195_residues
MNILRIGLVSVSDRASSGIYQDKGIPALEEWLTSALTTPFEVETRLIPDEQSLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRQMPGFGEQMRQISLHYVPTAILSRQVGVIRKQALIINLPGQPKSIKETLEGVKDAQSNVVVAGIFA
SVPYCIQLLDGPYIETNTDVVVAFRPKSAIIDIKD
>Mature_195_residues
MNILRIGLVSVSDRASSGIYQDKGIPALEEWLTSALTTPFEVETRLIPDEQSLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRQMPGFGEQMRQISLHYVPTAILSRQVGVIRKQALIINLPGQPKSIKETLEGVKDAQSNVVVAGIFA
SVPYCIQLLDGPYIETNTDVVVAFRPKSAIIDIKD

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=167, Percent_Identity=35.3293413173653, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI10880983, Length=167, Percent_Identity=35.3293413173653, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1786190, Length=195, Percent_Identity=87.1794871794872, Blast_Score=358, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17564954, Length=141, Percent_Identity=39.0070921985816, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17136978, Length=146, Percent_Identity=31.5068493150685, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24638841, Length=146, Percent_Identity=31.5068493150685, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21215; Mature: 21215

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILRIGLVSVSDRASSGIYQDKGIPALEEWLTSALTTPFEVETRLIPDEQSLIEQTLCE
CCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
LVDEMGCHLVLTTGGTGPARRDVTPDATLAIADRQMPGFGEQMRQISLHYVPTAILSRQV
HHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVIRKQALIINLPGQPKSIKETLEGVKDAQSNVVVAGIFASVPYCIQLLDGPYIETNTDV
HHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEECCCCE
VVAFRPKSAIIDIKD
EEEECCCCEEEEECC
>Mature Secondary Structure
MNILRIGLVSVSDRASSGIYQDKGIPALEEWLTSALTTPFEVETRLIPDEQSLIEQTLCE
CCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
LVDEMGCHLVLTTGGTGPARRDVTPDATLAIADRQMPGFGEQMRQISLHYVPTAILSRQV
HHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVIRKQALIINLPGQPKSIKETLEGVKDAQSNVVVAGIFASVPYCIQLLDGPYIETNTDV
HHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEECCCCE
VVAFRPKSAIIDIKD
EEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]