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The map label for this gene is yjjV [H]

Identifier: 218927635

GI number: 218927635

Start: 454105

End: 454893

Strand: Direct

Name: yjjV [H]

Synonym: YPO0434

Alternate gene names: 218927635

Gene position: 454105-454893 (Clockwise)

Preceding gene: 218927634

Following gene: 218927636

Centisome position: 9.76

GC content: 52.85

Gene sequence:

>789_bases
ATGCCGTATTTTATCGATACCCACTGTCATTTTGACTTCCCTCCGTTCACCGGTGATGAAGCCGCGAGTTTAGCCTGTGC
GGCAGAGGCGAATGTCAGGCAATTGATCGTTCCTTCAGTCAAGGCCGCATATTTCTCCCGTATTTTGGCATTAGCCGATC
GTTATCCCCCCTTGTTTGCGGCTCTTGGCTTACACCCCCTGTATATTGCCGAACATGAGGATGCCGATCTGGCGGCACTG
GCATCGCATCTGGCAGATAAGCCACCGAAATTGGTCGCAATAGGGGAGATTGGCCTCGATCTGTATATGGATGAACCGCA
GTTTCCACATCAGTTAGTGATCCTGAATATGCAGCTTGAACTGGCCAAACAGCATGATTTGCCGGTTATTTTGCATTCAC
GTCGCTCACACGATCCACTGGCTGCAGCATTGCGTAAAGCCGCGTTGCCGCGCGCGGGTGTGATACATGGTTTTGCGGGC
AGCTTAGCGCAGGCGCAAGCCTTTATTCGCCTGGGTTATTACATTGGTGTGGGGGGGACCATCACTTATAAGCGAGCGCA
GAAAACCCGTCATGTTATGGCCTCATTGCCGCTCTCCTCGTTGCTCTTAGAAACCGATGCACCCGATATGCCTCTGGCGA
GTTTTCAAGGGCAAGCCAATCGCCCTGAACGAGCCGCCAATGTGTTTGCCGCCTTGTGTGAGTTGCGCCCAGAGCCAGCC
GATGAGATTGCGGCTGAGTTGATGTGTAATAGCCAGCGTTTATTTTCCCTTCCTCCCCTTCGTCCTTGA

Upstream 100 bases:

>100_bases
ACAAGCGGAGGCTAACTCTTTACCCGTCGATATCACTTTGCCACCGAATCTGACAAAAAAATAAAGGTAATACTGTGTGA
TGAGAACGCCAGATAAGCCG

Downstream 100 bases:

>100_bases
CGCTGCAGCGGTGTTAGCTTCTCTCACTCACCCGAATCACTTACTTGAGTAAGCTCATCGGGATTTGTTCGCTTGCTGCC
TTGCTGCAACGACAATGACG

Product: putative metalloenzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPYFIDTHCHFDFPPFTGDEAASLACAAEANVRQLIVPSVKAAYFSRILALADRYPPLFAALGLHPLYIAEHEDADLAAL
ASHLADKPPKLVAIGEIGLDLYMDEPQFPHQLVILNMQLELAKQHDLPVILHSRRSHDPLAAALRKAALPRAGVIHGFAG
SLAQAQAFIRLGYYIGVGGTITYKRAQKTRHVMASLPLSSLLLETDAPDMPLASFQGQANRPERAANVFAALCELRPEPA
DEIAAELMCNSQRLFSLPPLRP

Sequences:

>Translated_262_residues
MPYFIDTHCHFDFPPFTGDEAASLACAAEANVRQLIVPSVKAAYFSRILALADRYPPLFAALGLHPLYIAEHEDADLAAL
ASHLADKPPKLVAIGEIGLDLYMDEPQFPHQLVILNMQLELAKQHDLPVILHSRRSHDPLAAALRKAALPRAGVIHGFAG
SLAQAQAFIRLGYYIGVGGTITYKRAQKTRHVMASLPLSSLLLETDAPDMPLASFQGQANRPERAANVFAALCELRPEPA
DEIAAELMCNSQRLFSLPPLRP
>Mature_261_residues
PYFIDTHCHFDFPPFTGDEAASLACAAEANVRQLIVPSVKAAYFSRILALADRYPPLFAALGLHPLYIAEHEDADLAALA
SHLADKPPKLVAIGEIGLDLYMDEPQFPHQLVILNMQLELAKQHDLPVILHSRRSHDPLAAALRKAALPRAGVIHGFAGS
LAQAQAFIRLGYYIGVGGTITYKRAQKTRHVMASLPLSSLLLETDAPDMPLASFQGQANRPERAANVFAALCELRPEPAD
EIAAELMCNSQRLFSLPPLRP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=229, Percent_Identity=31.4410480349345, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=28.6764705882353, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=29.0441176470588, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI225903439, Length=174, Percent_Identity=35.632183908046, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=28.158844765343, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226061595, Length=224, Percent_Identity=30.3571428571429, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=28.1853281853282, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI225903424, Length=277, Percent_Identity=26.7148014440433, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=64.3137254901961, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1787342, Length=265, Percent_Identity=28.3018867924528, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994985, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=213, Percent_Identity=27.6995305164319, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=22.1374045801527, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648690, Length=215, Percent_Identity=26.5116279069767, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28599; Mature: 28468

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYFIDTHCHFDFPPFTGDEAASLACAAEANVRQLIVPSVKAAYFSRILALADRYPPLFA
CCEEECCCEECCCCCCCCCHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALGLHPLYIAEHEDADLAALASHLADKPPKLVAIGEIGLDLYMDEPQFPHQLVILNMQLE
HHCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCEEEEEEEEEE
LAKQHDLPVILHSRRSHDPLAAALRKAALPRAGVIHGFAGSLAQAQAFIRLGYYIGVGGT
HHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCE
ITYKRAQKTRHVMASLPLSSLLLETDAPDMPLASFQGQANRPERAANVFAALCELRPEPA
EEHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCH
DEIAAELMCNSQRLFSLPPLRP
HHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure 
PYFIDTHCHFDFPPFTGDEAASLACAAEANVRQLIVPSVKAAYFSRILALADRYPPLFA
CEEECCCEECCCCCCCCCHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALGLHPLYIAEHEDADLAALASHLADKPPKLVAIGEIGLDLYMDEPQFPHQLVILNMQLE
HHCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCCEEEEEEEEEE
LAKQHDLPVILHSRRSHDPLAAALRKAALPRAGVIHGFAGSLAQAQAFIRLGYYIGVGGT
HHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCE
ITYKRAQKTRHVMASLPLSSLLLETDAPDMPLASFQGQANRPERAANVFAALCELRPEPA
EEHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCH
DEIAAELMCNSQRLFSLPPLRP
HHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]