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The map label for this gene is orn [H]

Identifier: 218927569

GI number: 218927569

Start: 378331

End: 378876

Strand: Direct

Name: orn [H]

Synonym: YPO0366

Alternate gene names: 218927569

Gene position: 378331-378876 (Clockwise)

Preceding gene: 218927565

Following gene: 218927571

Centisome position: 8.13

GC content: 46.7

Gene sequence:

>546_bases
ATGGCAGAAAATCAAAATAATCTGATCTGGATCGATCTGGAAATGACCGGTCTCGATCCAGAGCGGGATCGCATTATCGA
AATCGCTACCTTGGTCACTGATGCGAATCTTAATATTCTGGCAGAAGGACCTGTTCTGGCAGTCCATCAATCTGCTGAAC
AGCTTGGGCTAATGGATGAGTGGAATGTTCGTACCCATACTGGTAGTGGCTTGGTTGAGCGGGTGAAAGCCAGCCCCTTT
AATGACCGTGATGCTGAATTACAAACTATCGAATTCCTAAAACAGTGGGTCCCCGCGGGGGTTTCACCCATTTGCGGTAA
CAGTGTAGGTCAGGACCGCCGTTTCCTGTTCCGCTACATGCCAGAGCTTGAAGCGTATTTCCATTACCGCTATGTAGATG
TCAGTACATTGAAAGAGTTAGCGCGTCGCTGGAAACCTGAAATTCTGGCTGGTTTTAAAAAGCAAAATACCCATCAGGCA
TTGGATGACATTCGTGAGTCAGTCGCCGAGCTTGCTTACTATCGTGAGCATTTTATTCAATCTTAA

Upstream 100 bases:

>100_bases
GGATATATCGCTCGTTGCGACCAAAAGGACTATGATACACATTATTTTATTAATTAACCGTTTGTTCGGTTGCTCCCCCG
GCTTACAGATAGGAAATATC

Downstream 100 bases:

>100_bases
TTCCCTTCGGCCTTGAAACAGCAGGGGCGTTAGCTGCGCGCACTTACCCGAATCACTGACTGATGTAAGCTCATCGGGAC
GCGTTTGCTTGCTGCCTGCC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKASPF
NDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQA
LDDIRESVAELAYYREHFIQS

Sequences:

>Translated_181_residues
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKASPF
NDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQA
LDDIRESVAELAYYREHFIQS
>Mature_180_residues
AENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKASPFN
DRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQAL
DDIRESVAELAYYREHFIQS

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=169, Percent_Identity=50.2958579881657, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87082382, Length=180, Percent_Identity=86.6666666666667, Blast_Score=334, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI17557752, Length=178, Percent_Identity=48.876404494382, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=187, Percent_Identity=37.4331550802139, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355135, Length=175, Percent_Identity=46.8571428571429, Blast_Score=183, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20876; Mature: 20745

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDE
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCC
WNVRTHTGSGLVERVKASPFNDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQALDDIRESVAELAYYREHFIQ
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure 
AENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDE
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCC
WNVRTHTGSGLVERVKASPFNDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQALDDIRESVAELAYYREHFIQ
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA