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The map label for this gene is ykuT [H]

Identifier: 218906669

GI number: 218906669

Start: 5291723

End: 5292604

Strand: Reverse

Name: ykuT [H]

Synonym: BCAH820_5587

Alternate gene names: 218906669

Gene position: 5292604-5291723 (Counterclockwise)

Preceding gene: 218906671

Following gene: 218906668

Centisome position: 99.81

GC content: 35.71

Gene sequence:

>882_bases
ATGGATGTATTAACGAAGTGGTTTAATGCTACGAAACAGTATTTATTAGATGCTGATCGTTGGGCTGATATTGGAATTGC
AGCATTAAAAATATGTATCATTTTAACAATTGGTGCAATTGTAGTACGAATTGCAAGAGCGGTTGTACGAAATGCGTTTC
GTATGGGAAGTCGTTCGCCAATTCAAATTTCAGAACGTCGTACAGTTACAGTAGCGAAGTTACTTGAAAATATTGTGGCA
TACGTTGTTATGTTTATTATGTTAATTGCGATTTTAGGTGTGTTCAATATTAATGCATCAGGTTTATTAGCCGGTGCTGG
GGTAATTGGTTTAGCAGTCGGATTTGGTGCTCAAAGTTTAGTGAAAGATGTTATTACAGGATTATTTATCTTGTTAGAAG
ATCAATTTTCAGTTGGTGACTATGTGAAAATTGGTCAGTTTGAAGGTGTCGTTTTAGAAATTGGACTTCGTACAACGAAA
GTGAAAAGTTGGACAGGCGAAATTCATACTTTACCAAACGGAAGTATCGTTCAGGTTACCAACTATTCAGTTAGTAATAG
TGTAGCATTTGTTGACGTATCTATTTCGTATGAGGCTGATATAGCAAAAGCAGAGCAAGTCATTGAAGAATTATTAGAAG
AATTACCTGCACAATATGAGCAAATGGTAACAACGCCTCAGTTATTAGGCGTGCAAACATTAGCTGCATCAGAAGTTATA
TTACGTGTTATTGCAGAAGTAGAGCCGATGCAACATGCGGTTATTGCAAGAGCACTTCGTAAAGAAATTAAAAATCGTCT
AGATTTACATGGTATTGAAATTCCATATCCACGTATGGTTTTATATAATCGTGAAGAGTTAGTGAGTGGAAAAGCAATTT
AA

Upstream 100 bases:

>100_bases
AATGTAATTAAAGACATAAAATTTTTTCAGCAATTAGGAGACTTCTGATACAATAAGAAGGATAACTAAAAAGAAATTTT
GGCTGGAGAGGTAGAGGTAC

Downstream 100 bases:

>100_bases
TATGGAGAGGGGTTTGGAGAATGGAGCAAAAGCAGTATAACTTGTACGATGTTGTGGAAATGAAGAAAGCCCACCCATGT
GGGGAGAATCGTTGGAAGAT

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDVLTKWFNATKQYLLDADRWADIGIAALKICIILTIGAIVVRIARAVVRNAFRMGSRSPIQISERRTVTVAKLLENIVA
YVVMFIMLIAILGVFNINASGLLAGAGVIGLAVGFGAQSLVKDVITGLFILLEDQFSVGDYVKIGQFEGVVLEIGLRTTK
VKSWTGEIHTLPNGSIVQVTNYSVSNSVAFVDVSISYEADIAKAEQVIEELLEELPAQYEQMVTTPQLLGVQTLAASEVI
LRVIAEVEPMQHAVIARALRKEIKNRLDLHGIEIPYPRMVLYNREELVSGKAI

Sequences:

>Translated_293_residues
MDVLTKWFNATKQYLLDADRWADIGIAALKICIILTIGAIVVRIARAVVRNAFRMGSRSPIQISERRTVTVAKLLENIVA
YVVMFIMLIAILGVFNINASGLLAGAGVIGLAVGFGAQSLVKDVITGLFILLEDQFSVGDYVKIGQFEGVVLEIGLRTTK
VKSWTGEIHTLPNGSIVQVTNYSVSNSVAFVDVSISYEADIAKAEQVIEELLEELPAQYEQMVTTPQLLGVQTLAASEVI
LRVIAEVEPMQHAVIARALRKEIKNRLDLHGIEIPYPRMVLYNREELVSGKAI
>Mature_293_residues
MDVLTKWFNATKQYLLDADRWADIGIAALKICIILTIGAIVVRIARAVVRNAFRMGSRSPIQISERRTVTVAKLLENIVA
YVVMFIMLIAILGVFNINASGLLAGAGVIGLAVGFGAQSLVKDVITGLFILLEDQFSVGDYVKIGQFEGVVLEIGLRTTK
VKSWTGEIHTLPNGSIVQVTNYSVSNSVAFVDVSISYEADIAKAEQVIEELLEELPAQYEQMVTTPQLLGVQTLAASEVI
LRVIAEVEPMQHAVIARALRKEIKNRLDLHGIEIPYPRMVLYNREELVSGKAI

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=253, Percent_Identity=31.6205533596838, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789291, Length=281, Percent_Identity=27.4021352313167, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367355, Length=229, Percent_Identity=30.5676855895196, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787591, Length=164, Percent_Identity=28.6585365853659, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786670, Length=143, Percent_Identity=25.1748251748252, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32135; Mature: 32135

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLTKWFNATKQYLLDADRWADIGIAALKICIILTIGAIVVRIARAVVRNAFRMGSRSP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IQISERRTVTVAKLLENIVAYVVMFIMLIAILGVFNINASGLLAGAGVIGLAVGFGAQSL
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHH
VKDVITGLFILLEDQFSVGDYVKIGQFEGVVLEIGLRTTKVKSWTGEIHTLPNGSIVQVT
HHHHHHHHHHHEECCCCCCCEEEECCCCCEEEEECCCCEEEECCCCCEEECCCCCEEEEE
NYSVSNSVAFVDVSISYEADIAKAEQVIEELLEELPAQYEQMVTTPQLLGVQTLAASEVI
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRVIAEVEPMQHAVIARALRKEIKNRLDLHGIEIPYPRMVLYNREELVSGKAI
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHCCCCC
>Mature Secondary Structure
MDVLTKWFNATKQYLLDADRWADIGIAALKICIILTIGAIVVRIARAVVRNAFRMGSRSP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IQISERRTVTVAKLLENIVAYVVMFIMLIAILGVFNINASGLLAGAGVIGLAVGFGAQSL
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHH
VKDVITGLFILLEDQFSVGDYVKIGQFEGVVLEIGLRTTKVKSWTGEIHTLPNGSIVQVT
HHHHHHHHHHHEECCCCCCCEEEECCCCCEEEEECCCCEEEECCCCCEEECCCCCEEEEE
NYSVSNSVAFVDVSISYEADIAKAEQVIEELLEELPAQYEQMVTTPQLLGVQTLAASEVI
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRVIAEVEPMQHAVIARALRKEIKNRLDLHGIEIPYPRMVLYNREELVSGKAI
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]