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The map label for this gene is vpR [H]

Identifier: 218905551

GI number: 218905551

Start: 4193343

End: 4196096

Strand: Direct

Name: vpR [H]

Synonym: BCAH820_4436

Alternate gene names: 218905551

Gene position: 4193343-4196096 (Clockwise)

Preceding gene: 218905549

Following gene: 218905552

Centisome position: 79.08

GC content: 37.55

Gene sequence:

>2754_bases
ATGAAAAAAACTACATCTACACTTTTAAGTGTGGCACTCGTCTTTTCTAGTTTTGGAGCTTTAAGCGCCCATGCTGAATC
ACTGCAAAAGGAGAAGCAATTTAGTCCACAACTAAAAACAACGATTGAACAATGGGGAGAAAGTAAAATTGCTCAACACG
TTGAAACAAAAACAACAAAAGAAATATCTGTAATTGTAGAATTGCAACATGCACCTCTTGCTGCGCAAAGTAACATTCAG
CATGCTCCAGATTTACAAAATAGTCATGCACAGTCTTATCATACCGAGCTAAAAAAAGCACAAGAAGAGACGACTAAGAA
AATAAAAGAAAAAGCACCTGGTGCAAAAATTAAAGAAGTTTATAATACGTTATTTTCTGGTTTCTCTATTTCAGTTCCAG
GAGATCAAATTACTGCTCTTGCTTCTTTACCTGAAGTAAAGACAGTCTATCCGAACTTAACATATAAATTGCATGAAACA
ACGAAAAGCGCTACTAGCGAAGAAGCACCTAATATTGGTGGACCGACAATTGGTGCTCCTGAAGCATGGAATTTAAAAGA
CCCATCTGGTAAATCTCTTGATGGAAAAGGTATGAAAGTAGCGATTATCGATTCTGGCGTAGACTATACACATCCTGACT
TAAAGGCAAATTATATTGGTGGATACGACACAGTGGATGAAGATGATGATCCAATGGATGGTAACGTACACGGTACTCAT
GTAGCTGGAATTATTGCTGGTAATGGAAAAATTAAAGGCGTTGCTCCAAATGCTTCTATTTTAGCTTATCGTGTCATGAA
TGACGGTGGTACTGGTACAACAGATGATATTATTCAAGGTATTGAACGAGCAATTCAAGATGGTGCTGATGTGTTAAATC
TATCCCTTGGACAAGATTTAAATGTACCTGATCAGCCTGTAACTTTAACGTTAGAACGTGCAGCAAAGCTTGGGGTTACT
GCAGTCGTTTCCAATGGAAATGATGGTCCAAAACCTTGGTCTGTTGATGCACCTGGAAATGCAAGTAGCGTTATATCAGT
TGGAGCATCTACAGTTTCTATTCCGTTTCCAACATTCCAAGTAGCTGGTTCCAGCAAAACATACCAAGGATTACCGTTAT
CAAAATCAGATTTCCCAATAGGAAATGATTCTCCACTTGTATATGTTGGCTATGGTAATCCAAGCGATTATGCAAAACAA
GATGTGAAAGGAAAATTTGCACTTGTTTTACAAGGTACTTCTAGCACGTTAGTAAAAGCTGAACAAGCGAAGCAAGCTGG
TGCAATTGGTGTACTATTCATTTCTACAGAAAAAGAAATGAATATTATGCCTGAATACTTTACACGTGAAAACCTAGCCC
TTCCAGTTATGCAACTATCCAATGTAAACGGTGAAGAGTTGAAAAATTTAATTACAAAGCGTAAGAAAAATATAAAGATC
GGACAACCGGTTCCGACTGAATTAATTGGAAACTTTAGTTCCAGAGGTCCATCACAAGGAAGCTGGCTTATAAAACCAGA
TATCGTTGCACCTGGCGTACAAATTACTAGTACCGTACCACGAGGTGGCTATGAATCTCATAACGGAACAAGTATGGCTG
CTCCGCAAGTAGCTGGAGCGGTTGCCCTCCTGCGTCAAATGCACCCTGATTGGACGACGGAACAATTAAAAGCATCACTT
GCCAATACCGCAAAAACTTTAAAAGATGTGAATGAAAATACATATCCTATTATGACACAAGGATCTGGTTTAATTAACAT
CCCGAAAGCAGCTCAAACAGATGTATTAGTCAAACCTAACAATGTGAACTTCGGTCTTATTAAGCCAAACAGTGGTAAAG
TAAAACTGACGCAAAATATTACGTTACAAAATCTATCTAGTAAAAAGAAAAGTTTTTCAACTCGTGTGGAATTGCTAGAT
ACAAACACAAAAACAAAAGTAAAAACTTCTGTACCTTCATCGATTAGCATACAGCCGAATAGTAGTACCGAAAAACCATT
TACTATCACTGTCGATAGCTCACTACCACAAGGTGTGTATACTGGGAATGTATATGTAAAAGAGCAGGGAGCGAAAGAAG
AAACTCGCATTCCATTTACATTTAGTATCGATCCTAAAGATTACAAACGTATAGATGGACTCGAAATTATTAATTCTACA
TTTAGTCCAAATGGTGACCAAATATTAGACGATAATCTCATCAACTACTATTTAGTTGCACCTGTGGATGATGTAACATT
GCATGCAAATTTAGTTACAAAAGAACGTGTAACGTACCAAGGGATTATCCATCAAGCTAAAAATGAAACAGCTGGATACA
AACCTTTCAAATGGGATGGTACAAAAGCAGATGGTACTCCGTTAGCTGACGGTCTATACCAAATCGAAGCAGTTGCCTCT
AATTCTGGTGGGGAAACAAAACAAACAGCTGCTGTATTTCTTGATAGAACTGCACCTAAGTTAACATACGAAATTGACCA
AGAAAACCTTGTAATCACAGGAAAAGTGGATGATATCTTACTAGATTGGATGACAGAATCTGGTTGGGTAGCACCTGGAA
TTCCAGTGAGACTACAGTATGAAATCAACGGAAATGGTGTATGGGAAAGTGCATTCCTAAATCCTTGGGAGAAAAATTAC
GGCATTTATTTAGATCGTACTCAATTACAAGAAGGTAAAAATACAATTCACATTGTAGCAACAGATGAAGCTGGAAATAC
ATCTAATTTAAATGTTGATTTAGATGTGAAATAA

Upstream 100 bases:

>100_bases
GTCGAAAATATAGTTTAGCCAACATTCGTTTTTATATTTCACAATAAAAATGTAAGATAACTTTTTGGAATATTGGCACT
TTTTATTAGGGGGAGTTTCA

Downstream 100 bases:

>100_bases
AAAATTATTGTTGACAATTTTTTAAATATAGTTTTATAATACAAAACATAGTTTAGTTGAACGAATTATATATCGGCTTT
GAAGGAATACCAGTAGCGAC

Product: minor extracellular protease VpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 917; Mature: 917

Protein sequence:

>917_residues
MKKTTSTLLSVALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPVPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPNNVNFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRVELLD
TNTKTKVKTSVPSSISIQPNSSTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEETRIPFTFSIDPKDYKRIDGLEIINST
FSPNGDQILDDNLINYYLVAPVDDVTLHANLVTKERVTYQGIIHQAKNETAGYKPFKWDGTKADGTPLADGLYQIEAVAS
NSGGETKQTAAVFLDRTAPKLTYEIDQENLVITGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWESAFLNPWEKNY
GIYLDRTQLQEGKNTIHIVATDEAGNTSNLNVDLDVK

Sequences:

>Translated_917_residues
MKKTTSTLLSVALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPVPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPNNVNFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRVELLD
TNTKTKVKTSVPSSISIQPNSSTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEETRIPFTFSIDPKDYKRIDGLEIINST
FSPNGDQILDDNLINYYLVAPVDDVTLHANLVTKERVTYQGIIHQAKNETAGYKPFKWDGTKADGTPLADGLYQIEAVAS
NSGGETKQTAAVFLDRTAPKLTYEIDQENLVITGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWESAFLNPWEKNY
GIYLDRTQLQEGKNTIHIVATDEAGNTSNLNVDLDVK
>Mature_917_residues
MKKTTSTLLSVALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTKEISVIVELQHAPLAAQSNIQ
HAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEVYNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHET
TKSATSEEAPNIGGPTIGAPEAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDLNVPDQPVTLTLERAAKLGVT
AVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQVAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQ
DVKGKFALVLQGTSSTLVKAEQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
GQPVPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGAVALLRQMHPDWTTEQLKASL
ANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPNNVNFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRVELLD
TNTKTKVKTSVPSSISIQPNSSTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEETRIPFTFSIDPKDYKRIDGLEIINST
FSPNGDQILDDNLINYYLVAPVDDVTLHANLVTKERVTYQGIIHQAKNETAGYKPFKWDGTKADGTPLADGLYQIEAVAS
NSGGETKQTAAVFLDRTAPKLTYEIDQENLVITGKVDDILLDWMTESGWVAPGIPVRLQYEINGNGVWESAFLNPWEKNY
GIYLDRTQLQEGKNTIHIVATDEAGNTSNLNVDLDVK

Specific function: Not required for growth or sporulation [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=155, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71983555, Length=213, Percent_Identity=31.924882629108, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25141268, Length=213, Percent_Identity=31.924882629108, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=254, Percent_Identity=31.1023622047244, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324576, Length=251, Percent_Identity=29.0836653386454, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550681, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259
- InterPro:   IPR003137 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF02225 PA; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 98860; Mature: 98860

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER ; PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTTSTLLSVALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCC
EISVIVELQHAPLAAQSNIQHAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEV
EEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHETTKSATSEEAPNIGGPTIGAP
HHHHHCCCEEECCCCCEEHHHCCCCCEEECCCCEEEEECCHHCCCCCCCCCCCCCCCCCC
EAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDL
EEEEEECCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCC
NVPDQPVTLTLERAAKLGVTAVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQ
CCCCCCEEEEEEHHHHCCEEEEEECCCCCCCCEECCCCCCCCCEEEECCCEEEECCCCEE
VAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQDVKGKFALVLQGTSSTLVKA
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHH
EQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
HHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCC
GQPVPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGA
CCCCCHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VALLRQMHPDWTTEQLKASLANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCEEECCC
NVNFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRVELLDTNTKTKVKTSVPSSISIQPN
CCEEEEECCCCCCEEEEECCEEHHHHHHHHHHCEEEEEEECCCCEEEEECCCCEEEECCC
SSTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEETRIPFTFSIDPKDYKRIDGLEIINST
CCCCCCEEEEECCCCCCCEEECEEEEECCCCCCCCCCCEEEEECCHHHHHCCCHHHHHCC
FSPNGDQILDDNLINYYLVAPVDDVTLHANLVTKERVTYQGIIHQAKNETAGYKPFKWDG
CCCCCCEEECCCCEEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCEECCC
TKADGTPLADGLYQIEAVASNSGGETKQTAAVFLDRTAPKLTYEIDQENLVITGKVDDIL
CCCCCCCHHCCCEEEEEEECCCCCCCHHEEEEEEECCCCCEEEEECCCCEEEECCHHHHH
LDWMTESGWVAPGIPVRLQYEINGNGVWESAFLNPWEKNYGIYLDRTQLQEGKNTIHIVA
HHHHCCCCCCCCCCCEEEEEEECCCCEEHHHHCCCHHCCCCEEEEHHHHHCCCCEEEEEE
TDEAGNTSNLNVDLDVK
ECCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKKTTSTLLSVALVFSSFGALSAHAESLQKEKQFSPQLKTTIEQWGESKIAQHVETKTTK
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCC
EISVIVELQHAPLAAQSNIQHAPDLQNSHAQSYHTELKKAQEETTKKIKEKAPGAKIKEV
EEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YNTLFSGFSISVPGDQITALASLPEVKTVYPNLTYKLHETTKSATSEEAPNIGGPTIGAP
HHHHHCCCEEECCCCCEEHHHCCCCCEEECCCCEEEEECCHHCCCCCCCCCCCCCCCCCC
EAWNLKDPSGKSLDGKGMKVAIIDSGVDYTHPDLKANYIGGYDTVDEDDDPMDGNVHGTH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEE
VAGIIAGNGKIKGVAPNASILAYRVMNDGGTGTTDDIIQGIERAIQDGADVLNLSLGQDL
EEEEEECCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCC
NVPDQPVTLTLERAAKLGVTAVVSNGNDGPKPWSVDAPGNASSVISVGASTVSIPFPTFQ
CCCCCCEEEEEEHHHHCCEEEEEECCCCCCCCEECCCCCCCCCEEEECCCEEEECCCCEE
VAGSSKTYQGLPLSKSDFPIGNDSPLVYVGYGNPSDYAKQDVKGKFALVLQGTSSTLVKA
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEEEECCCCHHHHH
EQAKQAGAIGVLFISTEKEMNIMPEYFTRENLALPVMQLSNVNGEELKNLITKRKKNIKI
HHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCC
GQPVPTELIGNFSSRGPSQGSWLIKPDIVAPGVQITSTVPRGGYESHNGTSMAAPQVAGA
CCCCCHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
VALLRQMHPDWTTEQLKASLANTAKTLKDVNENTYPIMTQGSGLINIPKAAQTDVLVKPN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCCCCEEECCC
NVNFGLIKPNSGKVKLTQNITLQNLSSKKKSFSTRVELLDTNTKTKVKTSVPSSISIQPN
CCEEEEECCCCCCEEEEECCEEHHHHHHHHHHCEEEEEEECCCCEEEEECCCCEEEECCC
SSTEKPFTITVDSSLPQGVYTGNVYVKEQGAKEETRIPFTFSIDPKDYKRIDGLEIINST
CCCCCCEEEEECCCCCCCEEECEEEEECCCCCCCCCCCEEEEECCHHHHHCCCHHHHHCC
FSPNGDQILDDNLINYYLVAPVDDVTLHANLVTKERVTYQGIIHQAKNETAGYKPFKWDG
CCCCCCEEECCCCEEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCEECCC
TKADGTPLADGLYQIEAVASNSGGETKQTAAVFLDRTAPKLTYEIDQENLVITGKVDDIL
CCCCCCCHHCCCEEEEEEECCCCCCCHHEEEEEEECCCCCEEEEECCCCEEEECCHHHHH
LDWMTESGWVAPGIPVRLQYEINGNGVWESAFLNPWEKNYGIYLDRTQLQEGKNTIHIVA
HHHHCCCCCCCCCCCEEEEEEECCCCEEHHHHCCCHHCCCCEEEEHHHHHCCCCEEEEEE
TDEAGNTSNLNVDLDVK
ECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1938892; 7934828; 9384377; 10658653 [H]