Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 218905272

GI number: 218905272

Start: 3968006

End: 3969043

Strand: Reverse

Name: argC [H]

Synonym: BCAH820_4156

Alternate gene names: 218905272

Gene position: 3969043-3968006 (Counterclockwise)

Preceding gene: 218905274

Following gene: 218905271

Centisome position: 74.85

GC content: 37.67

Gene sequence:

>1038_bases
ATGAAAGTCGCGATTATTGGAGCAACTGGGTATGGAGGTATTGAGTTAATTCGGTTATTAGAGCAACATCCATATTTTTC
GATAGCATCTCTCCATTCTTTTTCACAAGTTGGCGAGTGTATAACAAATGTATATCCGCATTTTCAAAATGTTCTTGTTC
ATACGTTACAAGAAATTGATGTGGAGGAAATAGGGAAGGAAGCAGAAATTGTATTTTTAGCAACCCCAGCAGGAGTATCA
GCAGAGTTAACTCCAAAATTATTAGCAGTAGGTTTAAAAGTAATTGATTTATCTGGAGACTTTCGTATGAAAGATCCTTT
CATATATGAACAGTGGTATAAAAGGACAGCTGCAAAAGAAGGAGTTCTTAGGGAAGCTGTATATGGGTTAAGTGAATGGA
AAAGGTCCGAAATTCAAAAGGCAAATTTAATTGCAAACCCGGGATGTTTTGCTACAGCTGCATTATTAGCGATATTACCG
TTAGTTCGTAGCGGCATAATTGAAGAAGATTCAATTATTATTGATGCGAAATCAGGAGTATCTGGAGCAGGTAAAACGCC
AACAACGATGACTCACTTTCCTGAGTTATACGACAACTTGCGTATTTATAAAGTAAATGAGCATCAACACATTCCTGAGA
TTGAGCAAATGCTCGCGGAGTGGAATAGAGAAACGAAGCCAATCACGTTTAGTACACATTTAATACCGATATCACGTGGG
ATTATGGTTACACTGTATGCGAAAGTAAAGCGAGAAATGGAAATAGAACAACTTCAACAATTATATGAAGAAGCGTATGA
ACAATCGGCTTTTATTCGAATTCGCATGCAAGGAGAGTTTCCAAGTCCGAAAGAAGTGAGAGGCTCAAATTATTGTGATA
TGGGGATAGCTTACGATGAAAGAACAGGAAGAGTGACAATTGTTTCTGTTATAGACAATATGATGAAAGGTGCGGCTGGT
CAAGCGATTCAAAATGCAAATATAGTAGCGGGACTAGAAGAAACGACAGGTTTACAACATATGCCGCTTTATCTATAA

Upstream 100 bases:

>100_bases
GTTTTTTAAGTTTATAAAATTTATAAATATTTAATTGACTCTATAAATATACAATATTATAATCATACTTAATTTAAAGA
ATCAATATGAGGAGGAGCAT

Downstream 100 bases:

>100_bases
GGGGGGACATGATGATTAAAGTAGCGTCTATTACAAAAGTAGAAGATGGTTCGATTGTAACGCCAAAAGGTTTCTCGGCC
ATTGGCACTGCAATTGGTCT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIGKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRTAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL

Sequences:

>Translated_345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIGKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRTAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL
>Mature_345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIGKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRTAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=36.4431486880466, Blast_Score=204, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=346, Percent_Identity=28.6127167630058, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 38562; Mature: 38562

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01224 ARGC ; PS01034 GLYCOSYL_HYDROL_F16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEID
CEEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEIGKEAEIVFLATPAGVSAELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRTAAKE
HHHCCCCCEEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILPLVRSGIIEEDSIIIDAKSGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
CCCCCCCCHHHHCHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCC
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDE
EEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEC
RTGRVTIVSVIDNMMKGAAGQAIQNANIVAGLEETTGLQHMPLYL
CCCCEEEHHHHHHHHHCCCCCHHCCCCEEEECHHHCCCCCCCCCC
>Mature Secondary Structure
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEID
CEEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEIGKEAEIVFLATPAGVSAELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRTAAKE
HHHCCCCCEEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILPLVRSGIIEEDSIIIDAKSGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
CCCCCCCCHHHHCHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCC
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDE
EEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEC
RTGRVTIVSVIDNMMKGAAGQAIQNANIVAGLEETTGLQHMPLYL
CCCCEEEHHHHHHHHHCCCCCHHCCCCEEEECHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA