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The map label for this gene is cpdB [H]

Identifier: 218905263

GI number: 218905263

Start: 3958836

End: 3961178

Strand: Reverse

Name: cpdB [H]

Synonym: BCAH820_4147

Alternate gene names: 218905263

Gene position: 3961178-3958836 (Counterclockwise)

Preceding gene: 218905266

Following gene: 218905260

Centisome position: 74.7

GC content: 36.75

Gene sequence:

>2343_bases
GTGAAAAAGTCAAAAAAAATGCTGGCTGGAGCAACTCTTGCTATTGGGGTAATGGCGCCGCAAGTATTGCCAGCAACAGC
TCATGCGGATGAGAAAACTGGGGAGAGTACAGTTAACTTACGAATTCTAGAAACATCAGATATTCACGTTAACTTAATGA
ATTACGATTATTACCAAACGAAAACAGATAATAAAGTAGGTCTTGTGCAAACTGCAACACTTGTTAATAAAGCTCGTGAA
GAAGCGAAGAACTCTGTCCTATTTGATGATGGGGATGCATTACAAGGGACACCGCTTGGAGATTATGTAGCGAATAAAAT
AAATGATCCGAAGAAGCCTGTGGATCCTAGTTATACACATCCATTATATCGTTTAATGAATTTAATGAAGTATGACGTCA
TCTCTCTTGGGAATCATGAATTTAACTACGGTTTAGATTATTTAAACAAAGTGATTAGTAAAACAGAGTTCCCGGTTATT
AACTCAAACGTCTATAAAGATGATAAAGATAATAATGAAGAGAACGACCAAAATTACTTTAAACCATATCATGTTTTTGA
AAAAGAAGTAGAAGATGAATCAGGGCAAAAACAAAAAGTGAAAATTGGCGTAATGGGATTTGTTCCACCTCAAGTTATGA
ACTGGGATAAAGCAAATTTAGAAGGAAAAGTGAAAGCAAAAGATATAGTTGAAACAGCAAAGAAAATGGTGCCAAAAATG
AAAGCAGAAGGTGCAGATGTTATCGTTGCACTAGCGCATTCCGGTGTTGATAAGAGTGGATACAACGTCGGTATGGAAAA
CGCGTCGTATTATTTAACAGAGGTTCCTGGTGTAGATGCAGTATTAATGGGACATTCACATACTGAAGTGAAGGATGTAT
TTAATGGTGTTCCAGTTGTAATGCCTGGTGTCTTTGGAAGTAACTTAGGTATTATTGATATGCAATTGAAAAAAGTAAAT
GGAAAATGGGAAGTACAAAAAGAGCAATCGAAGCCGCAACTTCGTCCGATTGCTGATAGTAAAGGAAACCCACTCGTACA
ATCTGATCAAAATTTAGTTAATGAAATTAAAGATGATCATCAAGCGACAATTGATTATGTGAATACAGCTGTAGGAAAAA
CGACAGCGCCAATTAATAGTTATTTCTCATTAGTACAAGATGATCCTTCTGTACAACTTGTGACAAATGCACAGAAATGG
TATGTAGAAAAGTTATTTGCTGAAAATGGACAGTATAGTAAATATAAAGGAATTCCAGTTTTATCTGCAGGTGCACCATT
TAAAGCAGGTGGCCGAAACGGTGCTACATATTATACGGATATTCCAGCTGGAACGTTAGCGATTAAAAACGTTGCAGATT
TATATGTATATCCAAATACGTTATATGCTGTAAAAGTAAATGGGGCACAAGTAAAAGAATGGCTTGAAATGTCTGCAGGT
CAGTTTAATCAAATTGATCCAAAGAAAACAGAAGAACAGCCATTAGTAAATATCGGATACCCTACATATAACTTTGATAT
TTTAGATGGCTTAAAATACGAAATTGATGTAACACAACCAGCGAAATACGATAAAGATGGAAAAGTTGTAAATGCTAATA
CGAATCGTATTATAAATATGACATATGAAGGTAAGCCAGTAGCTGACAATCAAGAGTTTATCGTCGCTACAAATAACTAT
CGTGGAAGTAGCCAAACGTTCCCAGGTGTAAGTAAAGGGGAAGTTGTATACCAATCACAAGATGAAACACGTCAAATCAT
TGTGAAGTATATGCAAGAAACACCAGTTATTGATCCGGCAGCAGATAAAAATTGGGCATTTAAACCGATTGTTGCAGATA
AATTAAATACAACATTTGATTCTTCACCGAATGCACAAAAGTATATAAAGAAAGATGGAAACATATCATATGTTGGACCA
TCTGAAAATGAATTCGCTAAATATGCAATTGATATAACGAAGAAGAACGATGATGATAAGGAAACTGGTGGAGAGAACCC
GACAACACCGCCAACCGGTGAAGGAGATAATGGAGAGAACCCGACAACACCGCCAACTGGTGAAGGAAATAATGGAGAGA
ACCCGACGACACCACCAACCGGTGAAGGAAACAATGGAGGAAATCCAACCACACCATCAACAGATGAAGGGAATAATGCT
GGATCTGGACAAACTACAACGGATAATCAAAACTCAAAAGAAACAACAACTGTAAGTGAGAACAAAGAAGAACGTGATTT
ACCGAAAACAGGTACAAGTGTTGCGTCTACAATTGGAGCAGGTTTGGCGTTTATCGGAGCTGGATTCCTTCTGTTATTTA
GAAGAAAGAAAGCAAATAGATAA

Upstream 100 bases:

>100_bases
ATGAAAATCGTGTATCTAATAGAAGAAAAAAGGTATGTGGTTAGAGACTGATAGAAATTCATTTCATTATTCTTTGGTAA
TTGTATAAGGGGGATTTTTT

Downstream 100 bases:

>100_bases
TCGAGAAATATAAAAAGGATTACCTTAATCGGTAATCCTTTTTCGTATATTATGAAATTGTTACTGCCTTTTCTTTCTTC
CATGAAAGGCCAAATCCAGT

Product: bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MKKSKKMLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKARE
EAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVI
NSNVYKDDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKM
KAEGADVIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN
GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW
YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG
QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY
RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP
SENEFAKYAIDITKKNDDDKETGGENPTTPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNA
GSGQTTTDNQNSKETTTVSENKEERDLPKTGTSVASTIGAGLAFIGAGFLLLFRRKKANR

Sequences:

>Translated_780_residues
MKKSKKMLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKARE
EAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVI
NSNVYKDDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKM
KAEGADVIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN
GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW
YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG
QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY
RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP
SENEFAKYAIDITKKNDDDKETGGENPTTPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNA
GSGQTTTDNQNSKETTTVSENKEERDLPKTGTSVASTIGAGLAFIGAGFLLLFRRKKANR
>Mature_780_residues
MKKSKKMLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQTKTDNKVGLVQTATLVNKARE
EAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTHPLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVI
NSNVYKDDKDNNEENDQNYFKPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKM
KAEGADVIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVVMPGVFGSNLGIIDMQLKKVN
GKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDHQATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKW
YVEKLFAENGQYSKYKGIPVLSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG
QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINMTYEGKPVADNQEFIVATNNY
RGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPAADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGP
SENEFAKYAIDITKKNDDDKETGGENPTTPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNA
GSGQTTTDNQNSKETTTVSENKEERDLPKTGTSVASTIGAGLAFIGAGFLLLFRRKKANR

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1790658, Length=645, Percent_Identity=46.2015503875969, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1786687, Length=260, Percent_Identity=25.3846153846154, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922444, Length=301, Percent_Identity=24.2524916943522, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573524, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 85489; Mature: 85489

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKKMLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQT
CCCCHHHHHCHHEEEEHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEECCEEEC
KTDNKVGLVQTATLVNKAREEAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTH
CCCCCEEEEHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYKDDKDNNEENDQNYF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHC
KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKM
CHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KAEGADVIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVV
HCCCCCEEEEEECCCCCCCCCEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHCCCCEE
MPGVFGSNLGIIDMQLKKVNGKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDH
ECCCCCCCCCEEEEEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLFAENGQYSKYKGIPV
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCEE
LSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG
EECCCCCCCCCCCCCEEEEECCCCCEECCCCEEEEEECCEEEEEEECHHHHHHHHHHCCC
QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINM
CCCCCCCCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCEEEEE
TYEGKPVADNQEFIVATNNYRGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPA
EECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCC
ADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFAKYAIDITKKNDDDK
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCH
ETGGENPTTPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNA
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGQTTTDNQNSKETTTVSENKEERDLPKTGTSVASTIGAGLAFIGAGFLLLFRRKKANR
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKSKKMLAGATLAIGVMAPQVLPATAHADEKTGESTVNLRILETSDIHVNLMNYDYYQT
CCCCHHHHHCHHEEEEHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEECCEEEC
KTDNKVGLVQTATLVNKAREEAKNSVLFDDGDALQGTPLGDYVANKINDPKKPVDPSYTH
CCCCCEEEEHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PLYRLMNLMKYDVISLGNHEFNYGLDYLNKVISKTEFPVINSNVYKDDKDNNEENDQNYF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCHHC
KPYHVFEKEVEDESGQKQKVKIGVMGFVPPQVMNWDKANLEGKVKAKDIVETAKKMVPKM
CHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KAEGADVIVALAHSGVDKSGYNVGMENASYYLTEVPGVDAVLMGHSHTEVKDVFNGVPVV
HCCCCCEEEEEECCCCCCCCCEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHCCCCEE
MPGVFGSNLGIIDMQLKKVNGKWEVQKEQSKPQLRPIADSKGNPLVQSDQNLVNEIKDDH
ECCCCCCCCCEEEEEEEECCCEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
QATIDYVNTAVGKTTAPINSYFSLVQDDPSVQLVTNAQKWYVEKLFAENGQYSKYKGIPV
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCEE
LSAGAPFKAGGRNGATYYTDIPAGTLAIKNVADLYVYPNTLYAVKVNGAQVKEWLEMSAG
EECCCCCCCCCCCCCEEEEECCCCCEECCCCEEEEEECCEEEEEEECHHHHHHHHHHCCC
QFNQIDPKKTEEQPLVNIGYPTYNFDILDGLKYEIDVTQPAKYDKDGKVVNANTNRIINM
CCCCCCCCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCEEEEE
TYEGKPVADNQEFIVATNNYRGSSQTFPGVSKGEVVYQSQDETRQIIVKYMQETPVIDPA
EECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCC
ADKNWAFKPIVADKLNTTFDSSPNAQKYIKKDGNISYVGPSENEFAKYAIDITKKNDDDK
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCH
ETGGENPTTPPTGEGDNGENPTTPPTGEGNNGENPTTPPTGEGNNGGNPTTPSTDEGNNA
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSGQTTTDNQNSKETTTVSENKEERDLPKTGTSVASTIGAGLAFIGAGFLLLFRRKKANR
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]