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The map label for this gene is ribH

Identifier: 218905252

GI number: 218905252

Start: 3949522

End: 3949983

Strand: Direct

Name: ribH

Synonym: BCAH820_4136

Alternate gene names: 218905252

Gene position: 3949522-3949983 (Clockwise)

Preceding gene: 218905251

Following gene: 218905261

Centisome position: 74.48

GC content: 39.61

Gene sequence:

>462_bases
ATGGTATTCGAAGGTCATTTAGTTGGTACAGGATTAAAAGTTGGGGTTGTTGTTGGACGTTTTAATGAATTTATTACAAG
TAAGTTACTAGGCGGAGCTTTAGATGGGTTAAAGCGTCACGGTGTAGAAGAAAACGATATTGATGTTGCTTGGGTTCCTG
GCGCATTCGAAATTCCTTTAATCGCTAAAAAGATGGCAAATAGCGGGAAGTATGATGCTGTTATTACGTTAGGTACAGTA
ATTCGAGGTGCTACAACACATTACGATTATGTTTGTAATGAAGTAGCAAAAGGTGTTGCATCTTTATCACTTCAAACAGA
CATCCCAGTTATTTTCGGTGTATTAACGACAGAAACGATTGAGCAAGCGATTGAACGCGCGGGCACGAAAGCTGGTAATA
AAGGCTATGAATCTGCAGTTGCTGCAATTGAAATGGCTCACTTATCAAAACACTGGGCATAA

Upstream 100 bases:

>100_bases
GTTGCAAATGCCAGCAAAAGAAGAGAATAAAACGTATTTACAAACGAAAGTAAACAAATTAGGACATTTATTAAACTTAT
AATTAAAGGAGAGATTTATT

Downstream 100 bases:

>100_bases
AAAATAAAAAGAGGCTGCGGCCTCTTTTTATTTTTTTACTTTTTTCCGTACATCTTTTATTAATTCATTCATTGTTTTTC
CTTCTGTTTGTATACGAAGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA

Sequences:

>Translated_153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA
>Mature_153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=150, Percent_Identity=54, Blast_Score=166, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324429, Length=147, Percent_Identity=38.0952380952381, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BACAA (C3P7P8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868413.1
- ProteinModelPortal:   C3P7P8
- SMR:   C3P7P8
- EnsemblBacteria:   EBBACT00000127425
- GeneID:   7849856
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4357
- GeneTree:   EBGT00050000002577
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16255; Mature: 16255

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPL
CEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHH
IAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETI
HHHHHCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPL
CEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHH
IAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETI
HHHHHCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EQAIERAGTKAGNKGYESAVAAIEMAHLSKHWA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA