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The map label for this gene is mtnU [H]

Identifier: 218905171

GI number: 218905171

Start: 3882036

End: 3882878

Strand: Reverse

Name: mtnU [H]

Synonym: BCAH820_4055

Alternate gene names: 218905171

Gene position: 3882878-3882036 (Counterclockwise)

Preceding gene: 218905178

Following gene: 218905170

Centisome position: 73.22

GC content: 34.52

Gene sequence:

>843_bases
GTGACAAATGATATAATCTTTCCAGTATTTTGTAAAGAAAAAAATGAGAATGGGGCTGAAAAAATGAAAGTCGCATGTAT
TCAAATGGATATTTTCTTTGGAGATGTAGAAAAAAATATTGAGAATGCTAAAAATAAAATAAGCGAAGCAATGAAGGAAA
GACCAGATGTTATCGTCTTACCAGAACTATGGACAACAGGTTATGATTTAACGAGACTTTCTGAAATTGCAGATAGGGAT
GGATTGGAAACGAAAGAAAAGTTGATAGAATGGTCGAAACAATATGGTGTACATATTGTTGGTGGTTCTATAGCAAAGCA
AACAGAACAAGGTGTTACAAATACAATGTATGTTGTAACGAATAAAGGAGAACTAGTTAATGAATACAGTAAAGTACATT
TATTTCAGCTTATGGATGAACATAAATATTTAATCGCTGGAAATAGTACAGGTGAATTTAAGTTAGATGATGTAGAGTGT
GCCGGCACAATTTGTTATGACATTCGTTTTCCAGAGTGGATGCGTGTTCATACTGCTAAAGGTGCAAAAGTTTTATTTGT
TGTAGCTGAATGGCCATTAGTTCGTTTAGCACATTGGCGTTTGCTATTACAAGCAAGAGCGGTTGAAAATCAGTGTTATG
TTGTTGCATGTAATAGGGCAGGAAAAGATCCAAATAATGAGTTTGCTGGTCATTCTTTAATTGTCGACCCTTGGGGCGAA
GTTGTTGTAGAAGCGAATGAAGAAGAATCAATTTTATTTGGAGAGCTTACATTCGAGAAAATTGAAGAAGTACGTAAAGG
AATTCCAGTTTTTGCAGATCGTCGTCCAGAATTATACAAATAA

Upstream 100 bases:

>100_bases
ACAAGTGAAGCAAAAAATTGTGTTGGCAATGATGTTACTATCTCAGAAGGTTGAAATAATTTCATACTTTCCACCTCTTT
TGAAAGTTGTTACAATTCTA

Downstream 100 bases:

>100_bases
AATGTTGACAAGTGATTTTTATTCTTGGTATAGTCTTCAACATAAAGTTAAAAATTCTAAAAAATTATATAACTCTTATC
AAGAGCAGGTGGAGGGATTT

Product: hydrolase, carbon-nitrogen family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTNDIIFPVFCKEKNENGAEKMKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRD
GLETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVEC
AGTICYDIRFPEWMRVHTAKGAKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGE
VVVEANEEESILFGELTFEKIEEVRKGIPVFADRRPELYK

Sequences:

>Translated_280_residues
MTNDIIFPVFCKEKNENGAEKMKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRD
GLETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVEC
AGTICYDIRFPEWMRVHTAKGAKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGE
VVVEANEEESILFGELTFEKIEEVRKGIPVFADRRPELYK
>Mature_279_residues
TNDIIFPVFCKEKNENGAEKMKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDG
LETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECA
GTICYDIRFPEWMRVHTAKGAKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEV
VVEANEEESILFGELTFEKIEEVRKGIPVFADRRPELYK

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=32.9588014981273, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI5031947, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI297632348, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI297632350, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786412, Length=258, Percent_Identity=32.5581395348837, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17556280, Length=259, Percent_Identity=32.8185328185328, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323383, Length=278, Percent_Identity=31.6546762589928, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322335, Length=305, Percent_Identity=26.2295081967213, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=34.3065693430657, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17933642, Length=257, Percent_Identity=27.2373540856031, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31965; Mature: 31834

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDIIFPVFCKEKNENGAEKMKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVL
CCCCEEEEEEEECCCCCCHHHHEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEE
PELWTTGYDLTRLSEIADRDGLETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVT
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEEEEEEE
NKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAK
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCEEECCEEEEEEECCCCEEEEECC
GAKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGE
CCEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCC
VVVEANEEESILFGELTFEKIEEVRKGIPVFADRRPELYK
EEEECCCCCCEEEEECCHHHHHHHHCCCCEEECCCCCCCC
>Mature Secondary Structure 
TNDIIFPVFCKEKNENGAEKMKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVL
CCCEEEEEEEECCCCCCHHHHEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEE
PELWTTGYDLTRLSEIADRDGLETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVT
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEEEEEEE
NKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAK
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCEEECCEEEEEEECCCCEEEEECC
GAKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGE
CCEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCC
VVVEANEEESILFGELTFEKIEEVRKGIPVFADRRPELYK
EEEECCCCCCEEEEECCHHHHHHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]