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The map label for this gene is patA [H]

Identifier: 218905143

GI number: 218905143

Start: 3856871

End: 3858034

Strand: Direct

Name: patA [H]

Synonym: BCAH820_4027

Alternate gene names: 218905143

Gene position: 3856871-3858034 (Clockwise)

Preceding gene: 218905142

Following gene: 218905149

Centisome position: 72.73

GC content: 37.8

Gene sequence:

>1164_bases
ATGGAACAATTCATTAATCCTAGAGTGAAGGACATCCAAATTTCTGGGATCCGTCAATTCTCTAACATGATTCAAAACTA
CGATAACCTTATCTCTTTAACAATTGGACAACCCGATTTTCCTACACCTTCTCTCGTAAAAGAAGCGGCAAAACGGGCTA
TTACAGAAAATTATACAAGCTACACACATAACGCTGGTTTACTAGAATTACGCAAGGCAGCTTGTAACTTTGTAAAAGAT
AACTACGATTTACATTATTCACCTGAAACCGAAACCATCGTTACAATTGGTGCCAGTGAAGCAATTGATGTTGCATTTCG
AACGATTTTAGAGCCAGGAACAGAAGTCATTTTACCTGCTCCTATTTATCCCGGATACGAGCCGATTATTCGATTATGCG
GTGCAACACCTATTTTTATCGATGTTCGTGAAACTGGCTTCCGTTTAACAGCCGAAGCACTGGAAAATGCTATTACAGAA
AAAACAAGATGCGTCGTACTGCCGTATCCTTCTAATCCAACTGGTGTCACTTTATCTAAAAAAGAACTACAAGATATTGC
AGATGTTTTAAAAGATAAAAATATTTTCGTCCTTTCTGATGAAATTTATAGTGAACTTGTATATGAACAAACACATACAT
CGATTGCTCATTTCCCAGAAATGCGCGAAAAGACTATCGTCATTAACGGCTTATCAAAATCGCATTCTATGACTGGCTGG
CGTATCGGTCTATTATTTGCACCAAGCTATTTAGCTGGGCATATATTAAAAGTTCATCAATACAACGTAACGTGCGCTAC
TTCAATCGCTCAATATGCTGCAATTGAAGCATTAACAGCTGCTAAAGATGCACCAAAAATGATGCGCCATCAATACAAAA
AACGCCGTGATTACGTATATAATAGACTTATTCAAATGGGCTTAACAGTTGAAAAGCCAACAGGTGCATTTTACTTATTC
CCATATGTTGGCCATTTAACATCTTCATCATTTGATTTTGCACTTGACCTTGTCAAAGAAGCTGGACTTGCCGTCGTTCC
TGGAACAGCATTCTCTGAATATGGTGAAGGCTACCTTCGCTTGTCTTATGCATATAGTATTGAAACTTTAAAAGAAGGCT
GTGACCGTTTAGAAGCCTTTCTACAACAAAAAGCTAAGAGTTAA

Upstream 100 bases:

>100_bases
TTCTATTATCCCTCTCTTTCTACGTAACATATACGCAAGCGAAATGATAGAAAATATGTTAAAATGAACTTAATTTTCAA
ACGGAAGAAAGGGAGATACA

Downstream 100 bases:

>100_bases
ACTCTTAGCTTTTTGTTGCATAATGATCGCAAGTTTGACGCTTCAGTAATTTATGCGGAATAATAATACACTTTGCAGTA
GACTCCGCATTCTCTACTTT

Product: aminotransferase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEQFINPRVKDIQISGIRQFSNMIQNYDNLISLTIGQPDFPTPSLVKEAAKRAITENYTSYTHNAGLLELRKAACNFVKD
NYDLHYSPETETIVTIGASEAIDVAFRTILEPGTEVILPAPIYPGYEPIIRLCGATPIFIDVRETGFRLTAEALENAITE
KTRCVVLPYPSNPTGVTLSKKELQDIADVLKDKNIFVLSDEIYSELVYEQTHTSIAHFPEMREKTIVINGLSKSHSMTGW
RIGLLFAPSYLAGHILKVHQYNVTCATSIAQYAAIEALTAAKDAPKMMRHQYKKRRDYVYNRLIQMGLTVEKPTGAFYLF
PYVGHLTSSSFDFALDLVKEAGLAVVPGTAFSEYGEGYLRLSYAYSIETLKEGCDRLEAFLQQKAKS

Sequences:

>Translated_387_residues
MEQFINPRVKDIQISGIRQFSNMIQNYDNLISLTIGQPDFPTPSLVKEAAKRAITENYTSYTHNAGLLELRKAACNFVKD
NYDLHYSPETETIVTIGASEAIDVAFRTILEPGTEVILPAPIYPGYEPIIRLCGATPIFIDVRETGFRLTAEALENAITE
KTRCVVLPYPSNPTGVTLSKKELQDIADVLKDKNIFVLSDEIYSELVYEQTHTSIAHFPEMREKTIVINGLSKSHSMTGW
RIGLLFAPSYLAGHILKVHQYNVTCATSIAQYAAIEALTAAKDAPKMMRHQYKKRRDYVYNRLIQMGLTVEKPTGAFYLF
PYVGHLTSSSFDFALDLVKEAGLAVVPGTAFSEYGEGYLRLSYAYSIETLKEGCDRLEAFLQQKAKS
>Mature_387_residues
MEQFINPRVKDIQISGIRQFSNMIQNYDNLISLTIGQPDFPTPSLVKEAAKRAITENYTSYTHNAGLLELRKAACNFVKD
NYDLHYSPETETIVTIGASEAIDVAFRTILEPGTEVILPAPIYPGYEPIIRLCGATPIFIDVRETGFRLTAEALENAITE
KTRCVVLPYPSNPTGVTLSKKELQDIADVLKDKNIFVLSDEIYSELVYEQTHTSIAHFPEMREKTIVINGLSKSHSMTGW
RIGLLFAPSYLAGHILKVHQYNVTCATSIAQYAAIEALTAAKDAPKMMRHQYKKRRDYVYNRLIQMGLTVEKPTGAFYLF
PYVGHLTSSSFDFALDLVKEAGLAVVPGTAFSEYGEGYLRLSYAYSIETLKEGCDRLEAFLQQKAKS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=29.5918367346939, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=29.5918367346939, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI95147551, Length=411, Percent_Identity=25.3041362530414, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI169881279, Length=411, Percent_Identity=25.3041362530414, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI169881281, Length=409, Percent_Identity=22.7383863080685, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=26.3707571801567, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19263340, Length=439, Percent_Identity=22.0956719817768, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=22.3618090452261, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI187936925, Length=397, Percent_Identity=22.9219143576826, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI14211921, Length=397, Percent_Identity=22.9219143576826, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI149944424, Length=221, Percent_Identity=27.1493212669683, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788722, Length=369, Percent_Identity=28.9972899728997, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=27.8236914600551, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1788627, Length=402, Percent_Identity=25.3731343283582, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787710, Length=371, Percent_Identity=25.8760107816712, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=26.4631043256997, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=26.4631043256997, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=362, Percent_Identity=27.6243093922652, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=24, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=431, Percent_Identity=22.737819025522, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=25.8397932816537, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=396, Percent_Identity=24.7474747474747, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573069, Length=417, Percent_Identity=26.378896882494, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646114, Length=417, Percent_Identity=26.378896882494, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573067, Length=417, Percent_Identity=26.378896882494, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28573065, Length=417, Percent_Identity=26.378896882494, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24641770, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641760, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641768, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641766, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641764, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45551451, Length=435, Percent_Identity=23.9080459770115, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43354; Mature: 43354

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFINPRVKDIQISGIRQFSNMIQNYDNLISLTIGQPDFPTPSLVKEAAKRAITENYTS
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
YTHNAGLLELRKAACNFVKDNYDLHYSPETETIVTIGASEAIDVAFRTILEPGTEVILPA
HCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECC
PIYPGYEPIIRLCGATPIFIDVRETGFRLTAEALENAITEKTRCVVLPYPSNPTGVTLSK
CCCCCHHHHHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCEEECH
KELQDIADVLKDKNIFVLSDEIYSELVYEQTHTSIAHFPEMREKTIVINGLSKSHSMTGW
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCCE
RIGLLFAPSYLAGHILKVHQYNVTCATSIAQYAAIEALTAAKDAPKMMRHQYKKRRDYVY
EEEEEECCHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NRLIQMGLTVEKPTGAFYLFPYVGHLTSSSFDFALDLVKEAGLAVVPGTAFSEYGEGYLR
HHHHHHCCEEECCCCCEEEECHHHHHCCCCHHHHHHHHHHCCCEEECCCHHHHHCCCEEE
LSYAYSIETLKEGCDRLEAFLQQKAKS
EEEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQFINPRVKDIQISGIRQFSNMIQNYDNLISLTIGQPDFPTPSLVKEAAKRAITENYTS
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
YTHNAGLLELRKAACNFVKDNYDLHYSPETETIVTIGASEAIDVAFRTILEPGTEVILPA
HCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECC
PIYPGYEPIIRLCGATPIFIDVRETGFRLTAEALENAITEKTRCVVLPYPSNPTGVTLSK
CCCCCHHHHHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCCEEEEECCCCCCCEEECH
KELQDIADVLKDKNIFVLSDEIYSELVYEQTHTSIAHFPEMREKTIVINGLSKSHSMTGW
HHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCHHHCCCEEEEECCCCCCCCCCE
RIGLLFAPSYLAGHILKVHQYNVTCATSIAQYAAIEALTAAKDAPKMMRHQYKKRRDYVY
EEEEEECCHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NRLIQMGLTVEKPTGAFYLFPYVGHLTSSSFDFALDLVKEAGLAVVPGTAFSEYGEGYLR
HHHHHHCCEEECCCCCEEEECHHHHHCCCCHHHHHHHHHHCCCEEECCCHHHHHCCCEEE
LSYAYSIETLKEGCDRLEAFLQQKAKS
EEEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]