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The map label for this gene is speA [H]

Identifier: 218905093

GI number: 218905093

Start: 3813482

End: 3814954

Strand: Direct

Name: speA [H]

Synonym: BCAH820_3977

Alternate gene names: 218905093

Gene position: 3813482-3814954 (Clockwise)

Preceding gene: 218905091

Following gene: 218905094

Centisome position: 71.92

GC content: 38.22

Gene sequence:

>1473_bases
TTGTCCCAATACGAAACACCATTGTTTACCGCTTTAGTTGAGCACAGTAAGCGAAATCCAATTCAATTCCATATTCCAGG
TCATAAAAAAGGGCAAGGCATGGATCCTGAATTTCGCGAATTTATTGGGCATAATGCATTAGCAATTGATTTAATTAACA
TTGCGCCGCTCGATGATTTACATCATCCAAAAGGTATGATTAAAGAAGCACAAGATTTAGCAGCCGCTGCATTTGGTGCG
GATCATACTTTCTTTTCTATTCAAGGTACAAGTGGCGCAATAATGACAATGGTGATGAGCGTTTGCGGTCCTGGTGACAA
AATACTAGTGCCACGAAACGTGCATAAATCAGTAATGTCAGCTATTATTTTCTCAGGTGCAAAACCTATTTTCATGCATC
CTGAAATCGATCCAAAACTTGGTATTTCACATGGAATCACAATCCAATCTGTCAAAAAAGCACTTGAAGAGCACTCAGAT
GCGAAAGGCTTACTTGTTATTAATCCAACATACTTTGGCTTTGCTGCGGACTTAGAACAGATTGTACAATTAGCACATTC
TTACGATATCCCTGTACTCGTTGATGAGGCTCATGGTGTTCATATTCATTTTCACGATGAACTGCCGATGTCAGCGATGC
AAGCCGGTGCAGATATGGCAGCAACGAGTGTTCACAAATTAGGTGGATCTTTAACGCAAAGCTCTATTCTTAATGTAAAA
GAAGGCCTTGTGAACGTAAAACATGTTCAATCTATTATTAGCATGCTTACGACTACATCAACGTCTTACATCTTGTTAGC
CTCCCTAGATGTTGCTAGAAAACGTCTTGCTACAGAAGGAAAGGCGCTCATAGAACAAACAATACAATTAGCGGAACAAG
TTCGTAATGCTATAAATGATATTGAACATCTTTACTGTCCAGGGAAAGAAATGCTAGGTACGGATGCTACTTTTAACTAT
GATCCTACAAAGATAATTGTATCTGTAAAAGATTTAGGTATTACAGGCCATCAGGCTGAAGTATGGCTTAGAGAGCAATA
TAACATTGAAGTAGAACTCTCAGATTTATACAACATACTATGTCTTGTCACTTTTGGGGATACAGAAAGTGAGACGAATA
CACTTATTGCAGCATTACAAGATTTATCAGCAATATTTAAAAATAAAGCTGATAAAGGTGTTCGAATACAAGTAGAAATT
CCAGAAATACCTGTGTTAGCACTTTCTCCTCGAGATGCTTTTTATTCGGAAACAGAAGTCATCCCATTTGAAAATGCAGC
AGGTCGTATTATAGCTGATTTCGTTATGGTTTATCCGCCAGGGATTCCAATCTTTACTCCGGGGGAAATTATTACACAAG
ACAACTTAGAGTATATTCGTAAAAACTTAGAAGCAGGTTTACCTGTACAAGGTCCTGAAGATATGACATTACAAACATTA
CGCGTGATCAAAGAGTACAAGCCTATCAGTTGA

Upstream 100 bases:

>100_bases
AGAAAAACAAGTCTCATTCTAAAAAAGAACTTAACTTTTTTAGAACAAGATTATATAAAACAAACTCTAATAAATATTAA
AAAAAGAAGGGGTGTATAGA

Downstream 100 bases:

>100_bases
TAGGCTTTTTTTTCACCCTTTTTCCCTTTTCTCATACGATATTATGTAATGTAACGTATAGGTGGGGATACTACTATGAT
TGTAATAGGCCGTTCTATTG

Product: arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAAFGA
DHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSD
AKGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSILNVK
EGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKEMLGTDATFNY
DPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSAIFKNKADKGVRIQVEI
PEIPVLALSPRDAFYSETEVIPFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTLQTL
RVIKEYKPIS

Sequences:

>Translated_490_residues
MSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAAFGA
DHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSD
AKGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSILNVK
EGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKEMLGTDATFNY
DPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSAIFKNKADKGVRIQVEI
PEIPVLALSPRDAFYSETEVIPFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTLQTL
RVIKEYKPIS
>Mature_489_residues
SQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDLHHPKGMIKEAQDLAAAAFGAD
HTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMSAIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSDA
KGLLVINPTYFGFAADLEQIVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSILNVKE
GLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAINDIEHLYCPGKEMLGTDATFNYD
PTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNILCLVTFGDTESETNTLIAALQDLSAIFKNKADKGVRIQVEIP
EIPVLALSPRDAFYSETEVIPFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTLQTLR
VIKEYKPIS

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=550, Percent_Identity=24.5454545454545, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790573, Length=570, Percent_Identity=24.9122807017544, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI221142684, Length=380, Percent_Identity=27.3684210526316, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082193, Length=578, Percent_Identity=23.5294117647059, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786909, Length=604, Percent_Identity=23.6754966887417, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53784; Mature: 53652

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDL
CCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCC
HHPKGMIKEAQDLAAAAFGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMS
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHHHHH
AIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSDAKGLLVINPTYFGFAADLEQ
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHCHHHHHHH
IVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSILNVK
HHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHH
EGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAIND
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHLYCPGKEMLGTDATFNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNIL
HHHHCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEHHHHCEEE
CLVTFGDTESETNTLIAALQDLSAIFKNKADKGVRIQVEIPEIPVLALSPRDAFYSETEV
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCE
IPFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTLQTL
EECCCCCCHHHHHHHHCCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCCCCCCHHHHHH
RVIKEYKPIS
HHHHHCCCCC
>Mature Secondary Structure 
SQYETPLFTALVEHSKRNPIQFHIPGHKKGQGMDPEFREFIGHNALAIDLINIAPLDDL
CCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCC
HHPKGMIKEAQDLAAAAFGADHTFFSIQGTSGAIMTMVMSVCGPGDKILVPRNVHKSVMS
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHHHHH
AIIFSGAKPIFMHPEIDPKLGISHGITIQSVKKALEEHSDAKGLLVINPTYFGFAADLEQ
HHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHCHHHHHHH
IVQLAHSYDIPVLVDEAHGVHIHFHDELPMSAMQAGADMAATSVHKLGGSLTQSSILNVK
HHHHHHCCCCCEEEECCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHH
EGLVNVKHVQSIISMLTTTSTSYILLASLDVARKRLATEGKALIEQTIQLAEQVRNAIND
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHLYCPGKEMLGTDATFNYDPTKIIVSVKDLGITGHQAEVWLREQYNIEVELSDLYNIL
HHHHCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEHHHHCEEE
CLVTFGDTESETNTLIAALQDLSAIFKNKADKGVRIQVEIPEIPVLALSPRDAFYSETEV
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCE
IPFENAAGRIIADFVMVYPPGIPIFTPGEIITQDNLEYIRKNLEAGLPVQGPEDMTLQTL
EECCCCCCHHHHHHHHCCCCCCCEECCCCEEECCCHHHHHHHHCCCCCCCCCCCHHHHHH
RVIKEYKPIS
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]