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The map label for this gene is ctaD [H]

Identifier: 218905074

GI number: 218905074

Start: 3793965

End: 3795827

Strand: Reverse

Name: ctaD [H]

Synonym: BCAH820_3958

Alternate gene names: 218905074

Gene position: 3795827-3793965 (Counterclockwise)

Preceding gene: 218905075

Following gene: 218905073

Centisome position: 71.58

GC content: 38.86

Gene sequence:

>1863_bases
GTGAGTTCTGTAGCAAAAAAACAGGGGATGGGTGCTGTCATATGGGATTATTTAACGACAGTAGACCATAAAAAGATTGC
CATTCTCTATTTAATTGCAGGTGGATTGTTTTTTGTAATAGGCGGAATAGAAGCTCTATTTATTCGCCTTCAATTAGCGA
TTCCTAACAACGCTTTTCTTGTTGGGGATGCTTATAATCAAGTATTAACTATGCACGGTACAACAATGATTTTCCTCGCA
GCTATGCCACTCGTGTTTGCATTTATGAACGCCGCTGTACCACTTCAAATTGGTGCACGTGATGTAGCGTTCCCGTTTTT
GAATTCACTCGGATTTTGGTTATTTTTCTTTGGTGGAGTATTTTTAAATTTAAGTTGGTTTTTAGGTGGAGCACCTGATG
CAGGATGGACATCTTATGCATCTTTAGCTTTAGCCTCTAAAGGCCATGGTGTTGATTTTTATGTACTCGGCCTGCAAATC
TCCGGTATAGGTACATTAATTGGAGGCATCAACTTCCTTGTAACCATTATTAATATGCGTGCGCCAGGAATGACGTATAT
GCGTATGCCGATGTTTACATGGACGACATTTGTAACATCTTCGTTAATATTATTTGCTTTTCCGCCGTTAACTGTCGGAT
TAGGACTTTTAATGTTAGATCGCTTATTTGGAACAAGTTTCTTTAATCCAGCGCTGGGCGGGAATACAATTATATGGGAG
CATTTATTCTGGATTTTTGGTCATCCAGAAGTATACATTCTTATACTCCCAGCTTTCGGAATATTCTCAGAAATCTTCGC
TACATTTTCGAAAAAACGATTATTTGGTTATTCGTCGATGGTGTTTGCGACAGTATTAATTGGATTTTTAGGATTTATGG
TATGGGCGCATCATATGTTTACTGTTGGACTTGGTCCAGTTGCCAATGCTATTTTCTCAGTTGCAACAATGGCTATTGCG
GTTCCGACCGGTATTAAAATATTCAACTGGCTCTTTACAATGTGGGGCGGAAGTATTCGCTTTACGACACCTATGATGTG
GGCAGTAGCCTTCATTCCATCATTCGTAATGGGAGGAGTTACAGGTGTTATGCTAGCATCTGCACCAGCTGATTATCAAT
TTCATGATAACTATTTCGTAGTAGCTCATTTTCATTATGTAATCGTCGGCGGTGTTGTATTTGGTCTACTTGCAGGAGCG
CATTATTATTGGCCACTGATGTTTAATAAAATATTGAATGAGACATTAGGAAAGATAACATTTTGGTTATTCTTTATCGG
TTTCCATTTAACGTTCTTCATTCAGCATTTTCTTGGTTTAATTGGTATGCCGCGTCGTTACTACACATACCTTGAGGGAC
AAGGATTAGAGATGGGGAATATGATTAGTTCTATTGGAGCGGTATTTATGGCTCTTGGAACGATTGTTCTTTTATTCAAT
GTCATTAAAACGACAGTTTCAAAAGAAAAGGCAGGGCGTGATCCATGGGATGCTCGTACATTAGAATGGACAATGCCAGC
GCCTACACCGGAATATAACTTTAAACAATTGCCATTTGTTCGCGGGTTGGATCCGTTTTGGATTGAAAAACGCGAAGGGA
ATAAAGAGATGACAGCGGCAGAACCAGTTGGTGATATTCATATGCCAAATGCATCATTTTCACCATTTATCATTTCTTTA
GGATTGTTTATAGCGGCATTTGGTGCAATGTATATGCAAGGTGGAAAAGATAAGTTTTGGTTATTAGTAGCAATTATTGG
TTTAATCATTACGTTTGGTGCAATGTTCCTGCGTTCAGTAATCGATGATCATGGATATCATATTCATAAGGAAGATTTAG
AAGATAAGGGGGGCAAGGCGTAA

Upstream 100 bases:

>100_bases
CAACTTAACAGACGATCAAATTGATGCATTAAATGCATACTTACAAACGTTAAAAGTTGAAAAGTAAAGAGGGATTATTC
GCGAAGGGGAGGTTGAAAAC

Downstream 100 bases:

>100_bases
TGCATGTAGATGAAAAATTAACGAATGAAACATTTCCAGCAGAGCCTGAAAAAGCAACCCTTGAGGGGAAAAATAAGTTT
GTCGGTTTTTGGTTATTTCT

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSSVAKKQGMGAVIWDYLTTVDHKKIAILYLIAGGLFFVIGGIEALFIRLQLAIPNNAFLVGDAYNQVLTMHGTTMIFLA
AMPLVFAFMNAAVPLQIGARDVAFPFLNSLGFWLFFFGGVFLNLSWFLGGAPDAGWTSYASLALASKGHGVDFYVLGLQI
SGIGTLIGGINFLVTIINMRAPGMTYMRMPMFTWTTFVTSSLILFAFPPLTVGLGLLMLDRLFGTSFFNPALGGNTIIWE
HLFWIFGHPEVYILILPAFGIFSEIFATFSKKRLFGYSSMVFATVLIGFLGFMVWAHHMFTVGLGPVANAIFSVATMAIA
VPTGIKIFNWLFTMWGGSIRFTTPMMWAVAFIPSFVMGGVTGVMLASAPADYQFHDNYFVVAHFHYVIVGGVVFGLLAGA
HYYWPLMFNKILNETLGKITFWLFFIGFHLTFFIQHFLGLIGMPRRYYTYLEGQGLEMGNMISSIGAVFMALGTIVLLFN
VIKTTVSKEKAGRDPWDARTLEWTMPAPTPEYNFKQLPFVRGLDPFWIEKREGNKEMTAAEPVGDIHMPNASFSPFIISL
GLFIAAFGAMYMQGGKDKFWLLVAIIGLIITFGAMFLRSVIDDHGYHIHKEDLEDKGGKA

Sequences:

>Translated_620_residues
MSSVAKKQGMGAVIWDYLTTVDHKKIAILYLIAGGLFFVIGGIEALFIRLQLAIPNNAFLVGDAYNQVLTMHGTTMIFLA
AMPLVFAFMNAAVPLQIGARDVAFPFLNSLGFWLFFFGGVFLNLSWFLGGAPDAGWTSYASLALASKGHGVDFYVLGLQI
SGIGTLIGGINFLVTIINMRAPGMTYMRMPMFTWTTFVTSSLILFAFPPLTVGLGLLMLDRLFGTSFFNPALGGNTIIWE
HLFWIFGHPEVYILILPAFGIFSEIFATFSKKRLFGYSSMVFATVLIGFLGFMVWAHHMFTVGLGPVANAIFSVATMAIA
VPTGIKIFNWLFTMWGGSIRFTTPMMWAVAFIPSFVMGGVTGVMLASAPADYQFHDNYFVVAHFHYVIVGGVVFGLLAGA
HYYWPLMFNKILNETLGKITFWLFFIGFHLTFFIQHFLGLIGMPRRYYTYLEGQGLEMGNMISSIGAVFMALGTIVLLFN
VIKTTVSKEKAGRDPWDARTLEWTMPAPTPEYNFKQLPFVRGLDPFWIEKREGNKEMTAAEPVGDIHMPNASFSPFIISL
GLFIAAFGAMYMQGGKDKFWLLVAIIGLIITFGAMFLRSVIDDHGYHIHKEDLEDKGGKA
>Mature_619_residues
SSVAKKQGMGAVIWDYLTTVDHKKIAILYLIAGGLFFVIGGIEALFIRLQLAIPNNAFLVGDAYNQVLTMHGTTMIFLAA
MPLVFAFMNAAVPLQIGARDVAFPFLNSLGFWLFFFGGVFLNLSWFLGGAPDAGWTSYASLALASKGHGVDFYVLGLQIS
GIGTLIGGINFLVTIINMRAPGMTYMRMPMFTWTTFVTSSLILFAFPPLTVGLGLLMLDRLFGTSFFNPALGGNTIIWEH
LFWIFGHPEVYILILPAFGIFSEIFATFSKKRLFGYSSMVFATVLIGFLGFMVWAHHMFTVGLGPVANAIFSVATMAIAV
PTGIKIFNWLFTMWGGSIRFTTPMMWAVAFIPSFVMGGVTGVMLASAPADYQFHDNYFVVAHFHYVIVGGVVFGLLAGAH
YYWPLMFNKILNETLGKITFWLFFIGFHLTFFIQHFLGLIGMPRRYYTYLEGQGLEMGNMISSIGAVFMALGTIVLLFNV
IKTTVSKEKAGRDPWDARTLEWTMPAPTPEYNFKQLPFVRGLDPFWIEKREGNKEMTAAEPVGDIHMPNASFSPFIISLG
LFIAAFGAMYMQGGKDKFWLLVAIIGLIITFGAMFLRSVIDDHGYHIHKEDLEDKGGKA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=509, Percent_Identity=42.2396856581532, Blast_Score=379, Evalue=1e-105,
Organism=Escherichia coli, GI1786634, Length=610, Percent_Identity=45.7377049180328, Blast_Score=500, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6226519, Length=472, Percent_Identity=45.5508474576271, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=45.3703703703704, Blast_Score=263, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=37.9032258064516, Blast_Score=150, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 68762; Mature: 68631

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVAKKQGMGAVIWDYLTTVDHKKIAILYLIAGGLFFVIGGIEALFIRLQLAIPNNAFL
CCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEE
VGDAYNQVLTMHGTTMIFLAAMPLVFAFMNAAVPLQIGARDVAFPFLNSLGFWLFFFGGV
EECHHHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
FLNLSWFLGGAPDAGWTSYASLALASKGHGVDFYVLGLQISGIGTLIGGINFLVTIINMR
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHCC
APGMTYMRMPMFTWTTFVTSSLILFAFPPLTVGLGLLMLDRLFGTSFFNPALGGNTIIWE
CCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
HLFWIFGHPEVYILILPAFGIFSEIFATFSKKRLFGYSSMVFATVLIGFLGFMVWAHHMF
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
TVGLGPVANAIFSVATMAIAVPTGIKIFNWLFTMWGGSIRFTTPMMWAVAFIPSFVMGGV
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCH
TGVMLASAPADYQFHDNYFVVAHFHYVIVGGVVFGLLAGAHYYWPLMFNKILNETLGKIT
HHHHHCCCCCCCEECCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FWLFFIGFHLTFFIQHFLGLIGMPRRYYTYLEGQGLEMGNMISSIGAVFMALGTIVLLFN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIKTTVSKEKAGRDPWDARTLEWTMPAPTPEYNFKQLPFVRGLDPFWIEKREGNKEMTAA
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCHHEEECCCCCCCCCCC
EPVGDIHMPNASFSPFIISLGLFIAAFGAMYMQGGKDKFWLLVAIIGLIITFGAMFLRSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IDDHGYHIHKEDLEDKGGKA
HHCCCCEECHHHHCCCCCCC
>Mature Secondary Structure 
SSVAKKQGMGAVIWDYLTTVDHKKIAILYLIAGGLFFVIGGIEALFIRLQLAIPNNAFL
CCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEE
VGDAYNQVLTMHGTTMIFLAAMPLVFAFMNAAVPLQIGARDVAFPFLNSLGFWLFFFGGV
EECHHHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
FLNLSWFLGGAPDAGWTSYASLALASKGHGVDFYVLGLQISGIGTLIGGINFLVTIINMR
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHCC
APGMTYMRMPMFTWTTFVTSSLILFAFPPLTVGLGLLMLDRLFGTSFFNPALGGNTIIWE
CCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHH
HLFWIFGHPEVYILILPAFGIFSEIFATFSKKRLFGYSSMVFATVLIGFLGFMVWAHHMF
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
TVGLGPVANAIFSVATMAIAVPTGIKIFNWLFTMWGGSIRFTTPMMWAVAFIPSFVMGGV
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCH
TGVMLASAPADYQFHDNYFVVAHFHYVIVGGVVFGLLAGAHYYWPLMFNKILNETLGKIT
HHHHHCCCCCCCEECCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FWLFFIGFHLTFFIQHFLGLIGMPRRYYTYLEGQGLEMGNMISSIGAVFMALGTIVLLFN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIKTTVSKEKAGRDPWDARTLEWTMPAPTPEYNFKQLPFVRGLDPFWIEKREGNKEMTAA
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCHHEEECCCCCCCCCCC
EPVGDIHMPNASFSPFIISLGLFIAAFGAMYMQGGKDKFWLLVAIIGLIITFGAMFLRSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IDDHGYHIHKEDLEDKGGKA
HHCCCCEECHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]