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The map label for this gene is coaD

Identifier: 218905060

GI number: 218905060

Start: 3784670

End: 3785161

Strand: Reverse

Name: coaD

Synonym: BCAH820_3943

Alternate gene names: 218905060

Gene position: 3785161-3784670 (Counterclockwise)

Preceding gene: 218905061

Following gene: 218905058

Centisome position: 71.38

GC content: 35.77

Gene sequence:

>492_bases
ATGACAAGTATAGCTATTTCTTCGGGAAGTTTTGATCCAATTACCCTTGGGCATCTGGATATTATTAAAAGGGGAGCAAA
AGTATTTGACGAGGTATACGTAGTAGTTTTAAACAACTCGTCAAAAAAACCGTTCTTTTCAGTGGAAGAGCGCTTAGATT
TAATTCGAGAAGCCACAAAGGATATCCCTAATGTAAAAGTAGATTCACATAGTGGACTACTAGTTGAGTATGCGAAAATG
CGCAATGCGAATGCGATTTTACGTGGGTTACGAGCGGTTTCTGATTTTGAATATGAGATGCAAATTACTTCTATGAATCG
AAAATTAGATGAAAATATTGAAACCTTTTTTATTATGACAAACAATCAATATTCATTTTTAAGCTCGAGCATTGTGAAAG
AAGTTGCGAGATATGGAGGAAGTGTAGTAGATCTTGTCCCTCCTGTTGTAGAACGTGCTTTAAAAGAAAAGTTTCAAACC
CCGTTAAAGTGA

Upstream 100 bases:

>100_bases
TAGTTTTACCAGAGTCTATAGGAAGACTTGTAAAAGTGCGAGCTGAAAAATATGGCATTACAGCAATATCGATTTATAAG
TATGAAGGTGAGGGGACGGA

Downstream 100 bases:

>100_bases
ACGGGGTTTTTCTTTGTTGCTCCGAAAAAATAATAAGATGACATATACATATAAACAAAATAATGTAAATATTGGTCCGT
AGTGTACAAAAGATGTCCAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKM
RNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQT
PLK

Sequences:

>Translated_163_residues
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKM
RNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQT
PLK
>Mature_162_residues
TSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMR
NANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTP
LK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=46.2025316455696, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BACAA (C3P6T7)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868230.1
- ProteinModelPortal:   C3P6T7
- SMR:   C3P6T7
- EnsemblBacteria:   EBBACT00000129437
- GeneID:   7851840
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4161
- GeneTree:   EBGT00050000002538
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18379; Mature: 18248

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATK
CCEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHH
DIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMT
CCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATK
CEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHH
DIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMT
CCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA