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The map label for this gene is spoVD [H]

Identifier: 218905046

GI number: 218905046

Start: 3769443

End: 3771359

Strand: Reverse

Name: spoVD [H]

Synonym: BCAH820_3930

Alternate gene names: 218905046

Gene position: 3771359-3769443 (Counterclockwise)

Preceding gene: 218905047

Following gene: 218905045

Centisome position: 71.12

GC content: 37.82

Gene sequence:

>1917_bases
ATGCGTGTATCAAATGTAACGGTTAGAAAACGACTTATTTTTATACTTATATCAGGGATACTTATTTTCACTATCATCGA
TATTCGTCTTGGATATGTGCAATTTTTTCTTGGAAATATGTTAACGGATCGTGCGAAAGATTCATGGAGTCGTAATATTA
CTTTTGAACCTGAGCGTGGGAAGATTTTAGACCGAAATGGTGTGGAACTTGCTACGAATAAAAGTGCTCCAACTGTCTTT
GTTGTACCGAGGCAAATTGAAAAACCAGCAGAGACTGCAGAGAAGTTAGCTGCAGTATTAGGTGTGGAAAAAGATGAGAT
TTATAAGAGAATTACAAAAAAAGAATCAATTGTAAGGTTAGATAAAGGCGGAAGGAAAATATCACATGATAAAGCGAAAG
AGGTAAGAGGATTAAGTTTGAAAGGTGTTTATATCGCAGAGGACTCTATCCGATACTATCCATTTGGCAACTTTTTATCA
CACGTATTAGGGTTTGCAGGTAGTGATAACCAAGGTCTTATGGGGCTAGAAAAATATTATGATAAAGAACTAAATGGTGA
TGAAGGTCATGTGCGTTTTTTTGCAGATGCAAAAGGACAAAGGATGCCTAATGTTGGTGATGATTTCAAAAAACCAGAAG
CTGGTTTGAATTTAGGCTTAACAATTGATGCACGTATTAATAGAATTATGGAAAGAGAAATGAATATTGCAGAATCGACA
TACAATCCAGATGGTATGATTGCGATTGCGATGAATCCGAAAAATGGTGAAATTTTAGGTATGTCGAGTCGGCCGAGCTT
TGATCCAGCAGATTTTCAAAGTGTTTCTCCAGAAGTGTACAATAGAAATTTACCAGTATGGAGTACGTATGAGCCGGGTT
CAACATTTAAAATCATTACGTTAGCCGCAGCTTTGAATGAAAATTTAGTAGACTTAGAGAAAGATACGTTTTATGATGAT
GGAGCAGCTGAAGTTGGTGGAGCTAGATTGAAATGCTGGAAAGCAGGAGGCCACGGTAGCCAGACGTTTTTAGAAGTAGT
TCAAAACTCTTGTAACCCAGGATTTATTGAACTGGGTGATCGTCTTGGTAAAGAACGGTTGTTTAAATACATTCGTAATT
TCGGCTTTGGACAGAAAACTGGAATTGACCTGCAAGGTGAAGGTAGTGGGATTTTATTTAATTTAGATAAAGTCGGTCCA
GTCGAGCAAGCGACAACTTCATTCGGTCAAGGTGTTTCTGTTACGCCAATCCAACAAGTGGCGGCGGTAGCAGCGGCTAT
AAATGGTGGGACATTGTATCAACCGTATATAGCTAAAGAATTTATAGATCCGAAAAATAATCAAGTTGTAAGTAAAAAGA
CACCTGTGGACAAAAGAAAAGTTATTTCCAAGGAAACTTCAGAAAAAGTTCGGTATGCATTAGAGAATGTTGTAGCAAAG
GGATCTGGTAAAGGTGCTTTCATTGATGGGTATCGTGTAGGTGGAAAAACAGGTACGGCCCAAAAAGTGAAAGATGGTAA
ATATTTAGAGAATAATTATATCGTATCTTTTATCGGTTTTGCTCCAGCAGATGATCCAGAAATTGTTGTTTATGTAGCTG
TTGATAATCCGAAAGGTGTAACGCAATTTGGTGGAGTAGTAGCAGCTCCAATTGTTGGAAATATTCTTCGGGATGCACTT
CCTGTTATGGGAGTGAAACCGAGAAAAGAACAGGTTGAGAGAGAATATAAATGGGGCGATATACCAACTGTGGAAGTTCC
AAATTTAATTGGTATGAAAAAGAAAGATTTACAGACGCAACTCGTCGATTTGAAGCTTGATATAAGTGGAGACGGAGAGA
AAGTCATTAAACAGTCCCCAGAAGCAGGAGCTAAAGTGAAAGAAGGCTCAAAAATTAGAATTTACTTCGGGAATTAA

Upstream 100 bases:

>100_bases
AGAAGCAGAAAAACCGTAATGGTAAAAGAGAAGATGTTCTAATTAAATAAGTACAAGCATATATTGGAACAAGCTAGGCG
TAAGGGAGGCTTGTTCCAAT

Downstream 100 bases:

>100_bases
AGGTAACCTAGTACGTTTTATGGTACAATTGGTGGAAGTGAGTTCTTTATAGAAGAGTTACTTAATTTGAGGCCGTAAGA
GTCTCAGTTATAAATAAGTC

Product: sporulation specific penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MRVSNVTVRKRLIFILISGILIFTIIDIRLGYVQFFLGNMLTDRAKDSWSRNITFEPERGKILDRNGVELATNKSAPTVF
VVPRQIEKPAETAEKLAAVLGVEKDEIYKRITKKESIVRLDKGGRKISHDKAKEVRGLSLKGVYIAEDSIRYYPFGNFLS
HVLGFAGSDNQGLMGLEKYYDKELNGDEGHVRFFADAKGQRMPNVGDDFKKPEAGLNLGLTIDARINRIMEREMNIAEST
YNPDGMIAIAMNPKNGEILGMSSRPSFDPADFQSVSPEVYNRNLPVWSTYEPGSTFKIITLAAALNENLVDLEKDTFYDD
GAAEVGGARLKCWKAGGHGSQTFLEVVQNSCNPGFIELGDRLGKERLFKYIRNFGFGQKTGIDLQGEGSGILFNLDKVGP
VEQATTSFGQGVSVTPIQQVAAVAAAINGGTLYQPYIAKEFIDPKNNQVVSKKTPVDKRKVISKETSEKVRYALENVVAK
GSGKGAFIDGYRVGGKTGTAQKVKDGKYLENNYIVSFIGFAPADDPEIVVYVAVDNPKGVTQFGGVVAAPIVGNILRDAL
PVMGVKPRKEQVEREYKWGDIPTVEVPNLIGMKKKDLQTQLVDLKLDISGDGEKVIKQSPEAGAKVKEGSKIRIYFGN

Sequences:

>Translated_638_residues
MRVSNVTVRKRLIFILISGILIFTIIDIRLGYVQFFLGNMLTDRAKDSWSRNITFEPERGKILDRNGVELATNKSAPTVF
VVPRQIEKPAETAEKLAAVLGVEKDEIYKRITKKESIVRLDKGGRKISHDKAKEVRGLSLKGVYIAEDSIRYYPFGNFLS
HVLGFAGSDNQGLMGLEKYYDKELNGDEGHVRFFADAKGQRMPNVGDDFKKPEAGLNLGLTIDARINRIMEREMNIAEST
YNPDGMIAIAMNPKNGEILGMSSRPSFDPADFQSVSPEVYNRNLPVWSTYEPGSTFKIITLAAALNENLVDLEKDTFYDD
GAAEVGGARLKCWKAGGHGSQTFLEVVQNSCNPGFIELGDRLGKERLFKYIRNFGFGQKTGIDLQGEGSGILFNLDKVGP
VEQATTSFGQGVSVTPIQQVAAVAAAINGGTLYQPYIAKEFIDPKNNQVVSKKTPVDKRKVISKETSEKVRYALENVVAK
GSGKGAFIDGYRVGGKTGTAQKVKDGKYLENNYIVSFIGFAPADDPEIVVYVAVDNPKGVTQFGGVVAAPIVGNILRDAL
PVMGVKPRKEQVEREYKWGDIPTVEVPNLIGMKKKDLQTQLVDLKLDISGDGEKVIKQSPEAGAKVKEGSKIRIYFGN
>Mature_638_residues
MRVSNVTVRKRLIFILISGILIFTIIDIRLGYVQFFLGNMLTDRAKDSWSRNITFEPERGKILDRNGVELATNKSAPTVF
VVPRQIEKPAETAEKLAAVLGVEKDEIYKRITKKESIVRLDKGGRKISHDKAKEVRGLSLKGVYIAEDSIRYYPFGNFLS
HVLGFAGSDNQGLMGLEKYYDKELNGDEGHVRFFADAKGQRMPNVGDDFKKPEAGLNLGLTIDARINRIMEREMNIAEST
YNPDGMIAIAMNPKNGEILGMSSRPSFDPADFQSVSPEVYNRNLPVWSTYEPGSTFKIITLAAALNENLVDLEKDTFYDD
GAAEVGGARLKCWKAGGHGSQTFLEVVQNSCNPGFIELGDRLGKERLFKYIRNFGFGQKTGIDLQGEGSGILFNLDKVGP
VEQATTSFGQGVSVTPIQQVAAVAAAINGGTLYQPYIAKEFIDPKNNQVVSKKTPVDKRKVISKETSEKVRYALENVVAK
GSGKGAFIDGYRVGGKTGTAQKVKDGKYLENNYIVSFIGFAPADDPEIVVYVAVDNPKGVTQFGGVVAAPIVGNILRDAL
PVMGVKPRKEQVEREYKWGDIPTVEVPNLIGMKKKDLQTQLVDLKLDISGDGEKVIKQSPEAGAKVKEGSKIRIYFGN

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=563, Percent_Identity=29.4849023090586, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1786854, Length=622, Percent_Identity=23.9549839228296, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 70173; Mature: 70173

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSNVTVRKRLIFILISGILIFTIIDIRLGYVQFFLGNMLTDRAKDSWSRNITFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
KILDRNGVELATNKSAPTVFVVPRQIEKPAETAEKLAAVLGVEKDEIYKRITKKESIVRL
CEECCCCCEEEECCCCCEEEEECHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEE
DKGGRKISHDKAKEVRGLSLKGVYIAEDSIRYYPFGNFLSHVLGFAGSDNQGLMGLEKYY
CCCCCCCCCHHHHHHCCCEEEEEEEECCCEEEEECHHHHHHHHCCCCCCCCCCCHHHHHH
DKELNGDEGHVRFFADAKGQRMPNVGDDFKKPEAGLNLGLTIDARINRIMEREMNIAEST
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
YNPDGMIAIAMNPKNGEILGMSSRPSFDPADFQSVSPEVYNRNLPVWSTYEPGSTFKIIT
CCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEE
LAAALNENLVDLEKDTFYDDGAAEVGGARLKCWKAGGHGSQTFLEVVQNSCNPGFIELGD
EEEHHCCCCEECCCCCCCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHH
RLGKERLFKYIRNFGFGQKTGIDLQGEGSGILFNLDKVGPVEQATTSFGQGVSVTPIQQV
HCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHH
AAVAAAINGGTLYQPYIAKEFIDPKNNQVVSKKTPVDKRKVISKETSEKVRYALENVVAK
HHHHHHCCCCCEECCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GSGKGAFIDGYRVGGKTGTAQKVKDGKYLENNYIVSFIGFAPADDPEIVVYVAVDNPKGV
CCCCCEEEECEEECCCCCCCHHCCCCCEECCCEEEEEEECCCCCCCCEEEEEEECCCCCH
TQFGGVVAAPIVGNILRDALPVMGVKPRKEQVEREYKWGDIPTVEVPNLIGMKKKDLQTQ
HHHCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHEE
LVDLKLDISGDGEKVIKQSPEAGAKVKEGSKIRIYFGN
EEEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRVSNVTVRKRLIFILISGILIFTIIDIRLGYVQFFLGNMLTDRAKDSWSRNITFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
KILDRNGVELATNKSAPTVFVVPRQIEKPAETAEKLAAVLGVEKDEIYKRITKKESIVRL
CEECCCCCEEEECCCCCEEEEECHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEE
DKGGRKISHDKAKEVRGLSLKGVYIAEDSIRYYPFGNFLSHVLGFAGSDNQGLMGLEKYY
CCCCCCCCCHHHHHHCCCEEEEEEEECCCEEEEECHHHHHHHHCCCCCCCCCCCHHHHHH
DKELNGDEGHVRFFADAKGQRMPNVGDDFKKPEAGLNLGLTIDARINRIMEREMNIAEST
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
YNPDGMIAIAMNPKNGEILGMSSRPSFDPADFQSVSPEVYNRNLPVWSTYEPGSTFKIIT
CCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEE
LAAALNENLVDLEKDTFYDDGAAEVGGARLKCWKAGGHGSQTFLEVVQNSCNPGFIELGD
EEEHHCCCCEECCCCCCCCCCCHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHH
RLGKERLFKYIRNFGFGQKTGIDLQGEGSGILFNLDKVGPVEQATTSFGQGVSVTPIQQV
HCCHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHH
AAVAAAINGGTLYQPYIAKEFIDPKNNQVVSKKTPVDKRKVISKETSEKVRYALENVVAK
HHHHHHCCCCCEECCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GSGKGAFIDGYRVGGKTGTAQKVKDGKYLENNYIVSFIGFAPADDPEIVVYVAVDNPKGV
CCCCCEEEECEEECCCCCCCHHCCCCCEECCCEEEEEEECCCCCCCCEEEEEEECCCCCH
TQFGGVVAAPIVGNILRDALPVMGVKPRKEQVEREYKWGDIPTVEVPNLIGMKKKDLQTQ
HHHCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHEE
LVDLKLDISGDGEKVIKQSPEAGAKVKEGSKIRIYFGN
EEEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]