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The map label for this gene is rnc

Identifier: 218904979

GI number: 218904979

Start: 3700063

End: 3700800

Strand: Reverse

Name: rnc

Synonym: BCAH820_3863

Alternate gene names: 218904979

Gene position: 3700800-3700063 (Counterclockwise)

Preceding gene: 218904980

Following gene: 218904978

Centisome position: 69.79

GC content: 36.99

Gene sequence:

>738_bases
ATGCCGTACCGTAAATATAGAGAAAAAAAATACGAAACAAAATATCGTGAAGCGTTTAAATTATTTCAAGAAAAGATAGG
TATTACGTTTACAGATGAAAAATTATTGATTCAAGCATTTACGCATTCATCGTATGTGAATGAGCATCGAAAAAAACCAC
ATGAAGACAATGAGCGTCTCGAATTTCTTGGAGATGCAGTATTGGAACTTACTGTATCGCAGTATCTGTTTCAAAAATAT
CCGACAATGAGCGAAGGAGAGTTAACAAAACTACGTGCAGCAATTGTATGTGAACCATCTCTTGTTCGTTTTGCAAACGA
GTTGTCATTTGGTAGCCTTGTTTTATTAGGCAAAGGTGAGGAAATGACAGGTGGACGTGAACGACCAGCTTTATTAGCGG
ATGTCTTTGAAGCGTTTATTGGTGCCCTTTATCTTGATCAAGGGCTAGAAACAGTATGGGGCTTTTTAAAAGAAATTGTA
TACCCTAAAATTAATGAAGGTGCTTTTTCTCATGTGATGGATTATAAGAGTCAATTACAAGAGTTGATTCAGCGTGATGG
TAGTGGCAATATTGAGTATCAAATTTTGCAAGAAAAAGGCCCAGCCCACAATCGAGAATTTGTGTCACGTGTTACGTTAA
ATAACGTGGCTTTAGGACTTGGTAGTGGCAAGTCGAAAAAAGAAGCAGAACAACAAGCTGCTGCAGAAGCGTTGAAAAAG
TTAAAAGAACAACTATAA

Upstream 100 bases:

>100_bases
ACTGTTGGCGATGCTGTGACTTACATAGAGAGTCATCTATAATGCTTGAATGAAGTCCCGTTTTTTAGCGGGGCTTCTCG
GCTTATATCTGGAGGGACCT

Downstream 100 bases:

>100_bases
GGAATCCCCCTTTGAATGAGGGGGATTCCTTGTGCATAGAATGAAACTTTCTTTTCGTTTGTAAATGAAAGGAAAGGAAA
TCCGTATAAAAGTTGTTTTT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKY
PTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIV
YPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKK
LKEQL

Sequences:

>Translated_245_residues
MPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKY
PTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIV
YPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKK
LKEQL
>Mature_244_residues
PYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYP
TMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVY
PKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKL
KEQL

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030234, Length=225, Percent_Identity=35.1111111111111, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI155030236, Length=225, Percent_Identity=35.1111111111111, Blast_Score=120, Evalue=8e-28,
Organism=Escherichia coli, GI1788920, Length=223, Percent_Identity=35.4260089686099, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193202651, Length=244, Percent_Identity=32.7868852459016, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17506883, Length=244, Percent_Identity=32.7868852459016, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17552834, Length=266, Percent_Identity=27.8195488721804, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323895, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137682, Length=229, Percent_Identity=31.0043668122271, Blast_Score=104, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_BACAA (C3P5Q0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868086.1
- ProteinModelPortal:   C3P5Q0
- SMR:   C3P5Q0
- EnsemblBacteria:   EBBACT00000126794
- GeneID:   7849247
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4011
- GeneTree:   EBGT00050000002139
- ProtClustDB:   PRK00102
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 27993; Mature: 27862

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC
EMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKK
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHH
LKEQL
HHHCC
>Mature Secondary Structure 
PYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERL
CCHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC
EMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKK
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHH
LKEQL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA