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The map label for this gene is 218902905

Identifier: 218902905

GI number: 218902905

Start: 1689228

End: 1690487

Strand: Direct

Name: 218902905

Synonym: BCAH820_1788

Alternate gene names: NA

Gene position: 1689228-1690487 (Clockwise)

Preceding gene: 218902904

Following gene: 218902906

Centisome position: 31.86

GC content: 35.24

Gene sequence:

>1260_bases
ATGAGGGTAGAAGTATGGGGAGGAGCGGGAGAATACGGTCGTTCCTGCTATTTCGTAAAAAATAAAGAGACAAAAATATT
ATTTGATTGTGGTATTAATCGATCATATGAGGATAGTTATCCAAAAATAGAGCGGGAAGTTGTACCGTTTTTAGATGCAG
TATTTTTATCACATATTCATGAAGATCATACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATCTGG
ACAACTCGTTATACGAAGGAGCAACTTCCCGCTTATTATGAAAAATGGAGAAACTACAATGTGACGCAAGGATGGAATGT
ACCTTATAGTGACCAAAACATAAAAGATTTAAATTATGTATATGTTGATGAGATTAGTAATCCGAATGAATGGATACAAA
TTACTCCTTCATTGCGGTTTCAATGGGGATATAGTGGACATGTATTAGGGGCTGTTTGGTTTTTAGTGGATATGAGTCAT
ACATATGTATTTTATTCTGGCGATTATTCAGCAGAGTCTAACATACTACAAGCGAATTTACCTGAGAAATTGCGTGGCGA
TATAAAAGTTGCAATTGTAGATGCCGCGTATCATACTGATGATGTTTCGCAACATGAACGAGTAAACGAACTATGTGCAG
AAATTGAACGAGCTACGGGGCAAAAAGGGATAGCATTACTACCTTTGCCACCCCTTGGTAGGGCGCAAGATATCGTGTTG
TATTTATATAAAAAATATAAAGAACTTCCCATTATAGTAGATCAAGAAATTTTGGATGGATTCGAAGAAATGATCGTATA
TAAAGATTGGATCAAAAATAATGAAGAACTTGAAGAGCTGTTGGAGAGTTTAAAAAGAAACGTAATAGTTATGGATGATG
ACAGTGGTACGCAATATAGTTTTGGAATAGTTGTAATGAGTGATGCGAATATGCAAACGAAACGGGCTCAGTTATATTAT
GAACAAATTCGGCATGAAGAAAGAAATTCTATTATCTTTACTGGGCATGTTGCGAAAGGGAGTTTTGCAGAAAAAGTTTT
GAAAGAACGTATAGGTAAAGAATGTAGGGTGAAGCGAGTTCCATATAAAGTTCATCAAAGTATAAGAGATGTGAAAGAGA
TGTTAAATACATTATTACCGGAACATACGGTGTTAGTACACGCTTTAAAAGAGGATACAGATCGATTACAGAAAAAGCTT
AGCACGGCAGGGTATGAAAATGTATATTCACTTACTATGGAACGTATAGAAGTTATTTAA

Upstream 100 bases:

>100_bases
TATCTATTGGAATGGCGATGGCTGTCGTTTCAGTTGGACTTACAACGCTATGTTTATTACTTCTGCAGCATATGGAGCAA
AAACGAAAAGGGGTAGCATG

Downstream 100 bases:

>100_bases
CATGTAAAGGGGATAGGTATATGAAAAAAGTATTTGTATTCGTGAGTATTTTCTTTTGTTGTTTCCTTTATTCCGATAAG
GAAGGGTTTGCTGCTAGTCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYSDQNIKDLNYVYVDEISNPNEWIQITPSLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILQANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCAEIERATGQKGIALLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFEEMIVYKDWIKNNEELEELLESLKRNVIVMDDDSGTQYSFGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Sequences:

>Translated_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYSDQNIKDLNYVYVDEISNPNEWIQITPSLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILQANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCAEIERATGQKGIALLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFEEMIVYKDWIKNNEELEELLESLKRNVIVMDDDSGTQYSFGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI
>Mature_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYSDQNIKDLNYVYVDEISNPNEWIQITPSLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILQANLPEKLRGDIKVAIVDAAYHTDDVSQHERVNELCAEIERATGQKGIALLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFEEMIVYKDWIKNNEELEELLESLKRNVIVMDDDSGTQYSFGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=440, Percent_Identity=25.2272727272727, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=23.6902050113895, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32566029, Length=440, Percent_Identity=22.9545454545455, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=437, Percent_Identity=22.1967963386728, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323307, Length=440, Percent_Identity=23.1818181818182, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648013, Length=441, Percent_Identity=24.2630385487528, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI21358523, Length=433, Percent_Identity=22.6327944572748, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 48842; Mature: 48842

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYSDQNIKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YVDEISNPNEWIQITPSLRFQWGYSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILQANL
EEECCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
PEKLRGDIKVAIVDAAYHTDDVSQHERVNELCAEIERATGQKGIALLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
YLYKKYKELPIIVDQEILDGFEEMIVYKDWIKNNEELEELLESLKRNVIVMDDDSGTQYS
HHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCEEE
FGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEECC
PYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYSDQNIKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YVDEISNPNEWIQITPSLRFQWGYSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILQANL
EEECCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
PEKLRGDIKVAIVDAAYHTDDVSQHERVNELCAEIERATGQKGIALLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
YLYKKYKELPIIVDQEILDGFEEMIVYKDWIKNNEELEELLESLKRNVIVMDDDSGTQYS
HHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCEEE
FGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEECC
PYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]