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The map label for this gene is aroB [H]

Identifier: 218902728

GI number: 218902728

Start: 1520672

End: 1521757

Strand: Direct

Name: aroB [H]

Synonym: BCAH820_1611

Alternate gene names: 218902728

Gene position: 1520672-1521757 (Clockwise)

Preceding gene: 218902727

Following gene: 218902729

Centisome position: 28.68

GC content: 37.57

Gene sequence:

>1086_bases
ATGGGAAACATACATATTCAAACGAAATCAAAAGAATATGATGTATATGTAGGAAAAGAATCGTTGTCACATTTGACAAC
AATCGTTCAAAACATGCAGCCATCTGTATCAAATATTATGATCATTTCAGATGAAGCTGTTGCATCTTTACATTTACAGA
CAGTTGTAGACGCGTTGCAAATAGATCAAAAAGTATTTTCATTCGTTGTACCGAGTGGTGAAAAAGAGAAGTCCTTTGAA
AATTTCTATGCGGCTCATACGTCAGCTCTTGAAAATAAATTAGATAGAAATTCTTTAATTGTTGCACTTGGAGGTGGGAT
GATTGGAGATTTAGCTGGTTTTGTTGCTGCGTCGTTTATGCGTGGAATTCGCTTTGTTCAAGTTCCGACGACTTTATTAG
CTCACGATAGCGCGGTAGGTGGGAAAGTAGCAATCAATCATCCGTTAGGTAAAAATATGATAGGTGCATTCCATCAACCG
GAAGCAGTTGTATATCATACGCCATTTTTACAGTCTCTTCCTGAAAAAGAGTGGCGCTCAGGTTATGCAGAAGTGATAAA
ACATGCTCTAATTGGTGATGTAAAGCTATATCATTGGCTAAAAGAAGAAGTGCAAACATTAGCAGATCTTCGTGATGAGA
AATTAATCCATATATTAACGAAGGCAATTCCTGTAAAGGCAAACATTGTAGCACAAGATGAAACAGAAAAAGGTGTACGT
GCTCATTTGAACTTTGGACATACGTTAGGCCATGCTCTTGAAAAAGAACTAGGATATGGAAATATTACTCACGGTGACGG
AGTAGCGGTTGGAATGTTATTTGCTATATTCTTAAGTGAACAAGTGTATAAGGTGAATCTTGCTTATGAAGAGATGAAGC
AGTGGTTCTTGAAGTACGGCTATCCAAAAATGCCAAGTGATTTAAGTGTAGAACGCCTCGTCGGGTTGATGAAACAAGAT
AAGAAAGCGAATGCAGGGACAATTCATATGGTACTTATGCAGGAATATGGGGTAGTGAATGTCGTATCTATTTCTGATGA
GACTGTTCATATTGCGTTAGAGGCATTTCAAAAGGATATGGTTTAA

Upstream 100 bases:

>100_bases
GGGAATTAGCGACAGCTTTAATAGAACAATTCGGATTAGATCGTATGGACCTTATTCGTGAAAATATTGAGAAACATAAT
GAATATGCGAGGGGATTTTA

Downstream 100 bases:

>100_bases
AAACAAATGATAGAGAGTAGCCATGAAGTGCTTATTTTGAGGTGTTTTCGTAATAGTGACGGTTAGGATAAAAGATTGCA
ATAAAGGACTAAAATTGTAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSISDETVHIALEAFQKDMV

Sequences:

>Translated_361_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSISDETVHIALEAFQKDMV
>Mature_360_residues
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFEN
FYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPE
AVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVRA
HLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQDK
KANAGTIHMVLMQEYGVVNVVSISDETVHIALEAFQKDMV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=328, Percent_Identity=42.6829268292683, Blast_Score=235, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=32.7956989247312, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39996; Mature: 39864

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSISDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEEECCCCHHHHHHHHHHCC
V
C
>Mature Secondary Structure 
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSISDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEEECCCCHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA