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The map label for this gene is ubiE

Identifier: 218902724

GI number: 218902724

Start: 1516951

End: 1517664

Strand: Direct

Name: ubiE

Synonym: BCAH820_1607

Alternate gene names: 218902724

Gene position: 1516951-1517664 (Clockwise)

Preceding gene: 218902723

Following gene: 218902725

Centisome position: 28.61

GC content: 37.11

Gene sequence:

>714_bases
ATGCAACAATCAAAAGAAGAAAGAGTACATGATGTATTTGAGAAAATCTCTGATAAATACGATGTGATGAATTCTGTAAT
TAGTTTTCAAAGACATAAAGCGTGGCGCAAAGAGACGATGCGCATTATGGATGTAAAACCAGGTAGTAAAGCGCTTGATG
TATGTTGCGGGACAGCGGACTGGACAATTGCGCTAGCTGGAGCGGTGGGTGAACAGGGCAAGGTTGTTGGTTTAGACTTC
AGTGAAAATATGTTATCTGTTGGTAAGCAAAAGGTAGAGGCGTTACAATTAAAACAAGTAGAACTTCTACACGGGAATGC
AATGGAACTTCCATTTGAAGATAACACGTTTGATTATGTAACGATTGGATTTGGTTTACGTAATGTACCGGATTATATGC
ACGTATTAAAAGAAATGACGCGTGTAGTAAAACCAGGTGGAAAAGTAATTTGTTTAGAAACATCTCAACCAACAATGATT
GGTTTTCGACAAGGTTATATTTTATACTTTAAATATATCATGCCGTTATTTGGAAAGTTATTTGCGAAAAGTTATAAAGA
ATATTCATGGCTACAAGAATCTGCTAGTACATTCCCAGGTATGAAAGAATTGGCTAATATGTTCGAAAAAGCTGGACTTG
AACGTGTGCAAGTGAAGCCATTTACTTTTGGGGTAGCAGCGATGCATTTAGGCATGAAACCAGAATCAAAATAG

Upstream 100 bases:

>100_bases
ATCAATTTTTAGAAAATCACACAGATATAAGCGAAATAAACTCTGTGTTAAGAGATACATCGAAGACATAAGCAATTTTA
CATTGGAAGAAGGTACGAGC

Downstream 100 bases:

>100_bases
AAAAAAGAAGTTTTAGGTTAAGGTGAACAATATGAAGTTACAACTTATGTACTCTTTTTTACGATCGGATATTAATGTGA
TAGAAAAAGAATTAAAAAAG

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAGAVGEQGKVVGLDF
SENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK

Sequences:

>Translated_237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAGAVGEQGKVVGLDF
SENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK
>Mature_237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAGAVGEQGKVVGLDF
SENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2)

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family

Homologues:

Organism=Homo sapiens, GI116063536, Length=266, Percent_Identity=33.8345864661654, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI48994983, Length=233, Percent_Identity=39.9141630901288, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786404, Length=91, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557039, Length=236, Percent_Identity=33.8983050847458, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17561380, Length=183, Percent_Identity=25.1366120218579, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323526, Length=253, Percent_Identity=28.8537549407115, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641702, Length=243, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIE_BACAA (C3P5A0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866016.1
- ProteinModelPortal:   C3P5A0
- SMR:   C3P5A0
- EnsemblBacteria:   EBBACT00000128585
- GeneID:   7849069
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1603
- GeneTree:   EBGT00050000000522
- ProtClustDB:   PRK00216
- HAMAP:   MF_01813
- InterPro:   IPR014122
- InterPro:   IPR004033
- PANTHER:   PTHR10108:SF24
- TIGRFAMs:   TIGR02752
- TIGRFAMs:   TIGR01934

Pfam domain/function: PF01209 Ubie_methyltran

EC number: 2.1.1.-

Molecular weight: Translated: 26888; Mature: 26888

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS01183 UBIE_1; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCC
WTIALAGAVGEQGKVVGLDFSENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYV
CEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEE
TIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQGYILYFKYIMPLFGKL
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEHHCCHHHHHHHHHHHHHHH
FAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCC
WTIALAGAVGEQGKVVGLDFSENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYV
CEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEE
TIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQGYILYFKYIMPLFGKL
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEHHCCHHHHHHHHHHHHHHH
FAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA