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The map label for this gene is sirC [H]

Identifier: 218902636

GI number: 218902636

Start: 1434697

End: 1435314

Strand: Direct

Name: sirC [H]

Synonym: BCAH820_1519

Alternate gene names: 218902636

Gene position: 1434697-1435314 (Clockwise)

Preceding gene: 218902635

Following gene: 218902637

Centisome position: 27.06

GC content: 35.44

Gene sequence:

>618_bases
ATGTATCCACTTACAGTGCGAGTTGAGAAGAAACGTGTTGTTGTCATTGGTGGAGGGAAAGTTGCGGGATTTAAAATTAT
TCCTTTGCTAAAACAAGGTGCAGATATAGTTGTGGTAAGTCCTGAATTGGATGCGAATTTAGTGAAACTTGTAGAAGAAA
AGAAAATTCGTTGGTATCAAAGAGAATATGAAAAAAGTGATATTAATGGTGCTTTTTTAGTTGTAGCAGCGAGTAGTGAT
GCCGTATTGAACGAAAAGGTTGCTGAAGATACGGCAGAAAATCAGCTGGTAAATGTTATTACGAATCCGGAAAGTGGAAA
TGTTCATTTTCCGGCGGCGTTTCATCGCGGGCTACTTAATATAGCTGTTTCTACCGGGGGAGCGAGTCCGAAACTTGCAA
AAAAAATTCGAGATGATATCGCAAATAAATATGATGAGGCGTATGAATCATATCTTGATTTTTTATACGAAGTTAGAATA
AAGGTGAAAGAATTACAAATAGAGAAAAGAGAGAGAAATATATTGTTGCAAGAGGTATTGAAGTCAATATATGTTCAAAA
TGAACAAAAAAGAGAATTGTTTTTACAAGAATTAGAGAGAAGAGTTCATATAGGATGA

Upstream 100 bases:

>100_bases
GAGCTAGATGAGATAAAAATAAGTCCGTATTTAGGAAAGAATGAAGCGTTTCAGTATATGTTAATTCAGAAAACGAAGAA
ATTATTGAAGGGAGATCAAT

Downstream 100 bases:

>100_bases
TGAATAAATTGTACTTTACAACTATAAGAATATAATTTATAATCACAAGTAACTTCAATAGATGAAATCGATGAGCAAGA
AGAGTATGTATATTTGATAC

Product: precorrin-2 dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MYPLTVRVEKKRVVVIGGGKVAGFKIIPLLKQGADIVVVSPELDANLVKLVEEKKIRWYQREYEKSDINGAFLVVAASSD
AVLNEKVAEDTAENQLVNVITNPESGNVHFPAAFHRGLLNIAVSTGGASPKLAKKIRDDIANKYDEAYESYLDFLYEVRI
KVKELQIEKRERNILLQEVLKSIYVQNEQKRELFLQELERRVHIG

Sequences:

>Translated_205_residues
MYPLTVRVEKKRVVVIGGGKVAGFKIIPLLKQGADIVVVSPELDANLVKLVEEKKIRWYQREYEKSDINGAFLVVAASSD
AVLNEKVAEDTAENQLVNVITNPESGNVHFPAAFHRGLLNIAVSTGGASPKLAKKIRDDIANKYDEAYESYLDFLYEVRI
KVKELQIEKRERNILLQEVLKSIYVQNEQKRELFLQELERRVHIG
>Mature_205_residues
MYPLTVRVEKKRVVVIGGGKVAGFKIIPLLKQGADIVVVSPELDANLVKLVEEKKIRWYQREYEKSDINGAFLVVAASSD
AVLNEKVAEDTAENQLVNVITNPESGNVHFPAAFHRGLLNIAVSTGGASPKLAKKIRDDIANKYDEAYESYLDFLYEVRI
KVKELQIEKRERNILLQEVLKSIYVQNEQKRELFLQELERRVHIG

Specific function: Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin used as precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis [H]

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789768, Length=202, Percent_Identity=26.2376237623762, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: NA

EC number: =1.3.1.76 [H]

Molecular weight: Translated: 23261; Mature: 23261

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPLTVRVEKKRVVVIGGGKVAGFKIIPLLKQGADIVVVSPELDANLVKLVEEKKIRWYQ
CCCEEEEEECCEEEEEECCEECCEEEEEHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
REYEKSDINGAFLVVAASSDAVLNEKVAEDTAENQLVNVITNPESGNVHFPAAFHRGLLN
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEECHHHHCCHHE
IAVSTGGASPKLAKKIRDDIANKYDEAYESYLDFLYEVRIKVKELQIEKRERNILLQEVL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIYVQNEQKRELFLQELERRVHIG
HHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYPLTVRVEKKRVVVIGGGKVAGFKIIPLLKQGADIVVVSPELDANLVKLVEEKKIRWYQ
CCCEEEEEECCEEEEEECCEECCEEEEEHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
REYEKSDINGAFLVVAASSDAVLNEKVAEDTAENQLVNVITNPESGNVHFPAAFHRGLLN
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCEEECHHHHCCHHE
IAVSTGGASPKLAKKIRDDIANKYDEAYESYLDFLYEVRIKVKELQIEKRERNILLQEVL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIYVQNEQKRELFLQELERRVHIG
HHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA