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The map label for this gene is dhaK [H]

Identifier: 218902167

GI number: 218902167

Start: 1012709

End: 1014460

Strand: Direct

Name: dhaK [H]

Synonym: BCAH820_1049

Alternate gene names: 218902167

Gene position: 1012709-1014460 (Clockwise)

Preceding gene: 218902164

Following gene: 218902168

Centisome position: 19.1

GC content: 41.5

Gene sequence:

>1752_bases
ATGAAAAAGATTATAAACAAACCAGAAACATTAGTAATGGAAATGTGTAACGGAATGGTTATGGCTCATCCAGAGCTTGA
GCTTTTGAAAAAATATAAAGTCATTAAGAAGAAAGAAATGAATGAAAATAAAGTAACGTTAATTAGTGGCGGTGGTAGTG
GTCATGAGCCGGCACATGCAGGACTAGTCGGAAAAGGAATGCTAGATGCGGCAGTGTGCGGAGATGTGTTTGCGTCACCT
TCACAAATTCAGGTATATCAAGCAATTAAAGAGACAGCTAGTAAAAAAGGTACGTTATTAATTATTAAAAATTATAGCGG
CGATATTATGAATTTCAAAAACGGAGCGCATTTAGCGACGGAAGATGGAATTGAAGTAGATTACGTAAAAGTGGACGATG
ATATTGCGGTGGAAGATAGCTTGTATACAGTAGGAAGACGCGGCGTTGCGGGCGTTATTCTTGTTCATAAAATTGCCGGC
GCAGCAGCGGAAGCAGGTATGGATTTAGGAGCGGTGAAAGCTGTCGCAGAAAAAGCAGCTGCTAACGTGCGCACAATCGG
TTTAGCGCTAACGTCTTGTACTGTTCCGGCGAGCGGATCACCTACCTTCACACTTGCGGAAGATGAAATGGAATACGGCG
TAGGTATTCACGGTGAACCAGGAATTAAACGTGAAAAAATGTTGTCAGCAGATAAACTAGCGAACCGTATGACAAATGAT
TTAATGAAAGATTTAGGAGTAAAAGATGGCGAGGAAATTGCACTGCTAGTTAACGGTTTTGGCGGAACACCACTACAAGA
ACTTTACTTATTTAACAACGCAGTTACGAGAGAATTAGCTGCTAGAAACATTAAAATCAATAGAGTATTCGTCGGCAATT
ATATGACGAGTATCGATATGGCTGGTATGTCTTTAACAGTGATGAAATTAGATGATGAGTTAAAAACATTATTATCGAAA
GAGTGTAATACACCAGCGTTTAAAGTAGATGGGCCAGTTGAAAGTGTAGAGTACGTAAATGTGCTTGAAGAGACAGAAGA
GAAGGAAGTTTCATTTGAACTAGAAACAGCGGAAAAGCACGCAGTTATTAAAAATAATGTCATCACATTAAACAACATGA
TCTATCTCGTTGATAAAATGAGCGATATTATTATTAAAAATGAAGTACCGTTCTGTGAGTTAGATACACATGCAGGTGAC
GGCGACTTCGGAATGAGTGTGGCAAAAGGATTTAAGCAATTAAAACGTGAGTGGCATTCTATCGTGGAGCAAGAAAACGT
AACAATCGGATCATTCCTTGACGGTTGTTCGATGATTATTATGGAACATTGCGGCGGTGCATCTGGCCCAATTTGGGGCG
GAGCATTCCGAGCAGCTAGTAAAGCAGCAGGCGAAAAGCGTGAGTTAACAGTGAAAGAATTCGCTGAAATGTTGCAAGCA
GCACTGCAAGGTATACAATCTATCGGTGAAAGATCATTCGGCAGAGGAGCAGTAGTTGGTGACAAAACACTAGTTGACGC
ACTTGCTCCATGTGTAGACTCTTGGTTAGCTAGCGCTTCAAACGAAGAAGACATGAAAACTGCCTTTGAAAAAGGAGCAG
AAGCAGCGGTTAAAGGAGCAGAGTACACGAAAGAAATCGTAGCTCGCATGGGCCGCGCCGGTACAGTTGGTGAAAGAAGT
TTAGGCTATCCTGATGCAGGTGCGCATGCGCTTGGAGTTATCTTTACGGAGATTGCGGGTAGTTTGAAATAG

Upstream 100 bases:

>100_bases
TTTGTCCGTTTACTATAAAACGCTTTCATTTTAACATGGATAGTAAGAAGAAGATTTCAAATATATCACAATATATTAAA
GGAATTGAGGGAGAACTACA

Downstream 100 bases:

>100_bases
GAATTATGTTAGTGTGATAGAATCCCCTTCACGGTAAGTTGTTTACTGTGGAGGGGATTTTTTTAGTTGATATATATAAT
TTCATTAGATGTTCTCTCCA

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADKLANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEKHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Sequences:

>Translated_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADKLANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEKHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK
>Mature_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADKLANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEKHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=576, Percent_Identity=32.8125, Blast_Score=281, Evalue=2e-75,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=40.7932011331445, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI1787449, Length=212, Percent_Identity=28.7735849056604, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=581, Percent_Identity=31.3253012048193, Blast_Score=271, Evalue=7e-73,
Organism=Saccharomyces cerevisiae, GI6321055, Length=604, Percent_Identity=31.6225165562914, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6323570, Length=589, Percent_Identity=32.088285229202, Blast_Score=209, Evalue=7e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 62474; Mature: 62474

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADKLANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEKH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHCCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADKLANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEKH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHCCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]