Click here to switch to the map view.

The map label for this gene is dnaC [H]

Identifier: 218902142

GI number: 218902142

Start: 993285

End: 994571

Strand: Direct

Name: dnaC [H]

Synonym: BCAH820_1024

Alternate gene names: 218902142

Gene position: 993285-994571 (Clockwise)

Preceding gene: 218902141

Following gene: 218902144

Centisome position: 18.73

GC content: 43.12

Gene sequence:

>1287_bases
ATGAGTATTCAAAATGTGGAGGCGGAAAAGACGGTATTAGGTTCTCTATTACTTGATGGAGAGCTTATTAAAGAGTGCCG
TTTGACGGAGCAGTATTTTTCGATGCCGGTGCATAAGTCTATATTTCAGTTAATGCGAAAAATGGAAGAAGAGGGGCAAC
CGATTGATCTTGTGACGTTCATTTCTAGGGTAGATCCGAAGTTTTTAGAGGGGATCGGGGGAATGGAGTATTTTATAGGG
TTAATGGATGGTGTGCCTACTACTAGAAACTTCTCTTATTATGAGGGGCTTGTTCGAGGTGCCTGGAAAATGTATCAGGC
AGGTGTTCTTGGGCACAAGATGGGAGAGCGTCTTATTGCGGAGAAGAATGAGGAAATTATTGGTGAGACGATTACGGCAC
TTTGTGAGTTAGAGGAACAGGATTGTGTATGTGAGTTTGATTTGAAGGATGCGTTAGTTGATTTATATGAAGAGCTTCAT
CAAGATGCGAAAGAGATTACGGGTATTGAGACTGGTTATACGTCGCTCAATAAAATGACGTGCGGATTGCAGGAAGGTGA
TTTTGTCGTTCTTGGTGCGCGTCCTTCTATGGGAAAGACTGCGTTTGCGCTAAATGTTGGACTGCATGCGGCAAAGTCTG
GAGCGGCGGTTGGATTGTTTTCGTTAGAGATGAGTAGTAAGCAATTGTTAAAACGGATGGCGTCTTGTGTAGGTGAAGTG
TCAGGGGGCAGACTGAAAAATCCGAAGCACCGTTTTGCGATGGAAGATTGGGAAAAGGTGAGTAAGGCGTTTGCGGAGAT
TGGTGAACTGCCGCTTGAGATTTACGACAATGCAGGTGTTACGGTGCAAGATATTTGGATGCAAACTCGTAAGTTAAAGA
GGAAGCACGGTGATAAAAAGATTTTAATGATTGTAGATTACTTGCAGCTTATTACGGGCGATCCGAAGCATAAGGGCAAT
CGATTTCAGGAAATTAGTGAGATTTCGCGTAAGCTTAAGTTATTAGCACGTGAATTAAATGTTTGTGTAGTAGCATTATC
GCAATTGTCTCGTTCTGTAGAGTCACGGCAAGATAAGCGACCTCTTTTATCTGATTTAAGAGAGACAGGACAAATTGAAC
AAGATGCGGATGTCATTATGCTTATGTATCGCGAGGATTATTACGATAAGGAAACGAAGCAGAAAGAGATGACGGAGATT
CATGTGGCAAAGCATCGGAATGGGCCTGTTGGGAGTTTTAAGCTGCGGTTTATGAAGGAGTTTGGGCGGTTTGTGGAGGG
GAAATAG

Upstream 100 bases:

>100_bases
GGGAGACGGAGGAGTTTTTGGCGAGGTGTGAGGAATGGGAGAAGAATGCACCGTCTGAGGAAGAGTTGCAGCGCCTTTTA
GCGGAGCGCGGGTGGCGTCC

Downstream 100 bases:

>100_bases
TGAAAAGACTTGAGTATTACTTTGCATATAAAATAAAGCATAAGTTTTCCATTGTATTCACTTATGCTTTATTTTTTGAA
TATGTTCCTTATTTCCCCAT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEEEGQPIDLVTFISRVDPKFLEGIGGMEYFIG
LMDGVPTTRNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKNEEIIGETITALCELEEQDCVCEFDLKDALVDLYEELH
QDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILMIVDYLQLITGDPKHKGN
RFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQKEMTEI
HVAKHRNGPVGSFKLRFMKEFGRFVEGK

Sequences:

>Translated_428_residues
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEEEGQPIDLVTFISRVDPKFLEGIGGMEYFIG
LMDGVPTTRNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKNEEIIGETITALCELEEQDCVCEFDLKDALVDLYEELH
QDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILMIVDYLQLITGDPKHKGN
RFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQKEMTEI
HVAKHRNGPVGSFKLRFMKEFGRFVEGK
>Mature_427_residues
SIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEEEGQPIDLVTFISRVDPKFLEGIGGMEYFIGL
MDGVPTTRNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKNEEIIGETITALCELEEQDCVCEFDLKDALVDLYEELHQ
DAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEVS
GGRLKNPKHRFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILMIVDYLQLITGDPKHKGNR
FQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQKEMTEIH
VAKHRNGPVGSFKLRFMKEFGRFVEGK

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=38.0090497737557, Blast_Score=271, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48533; Mature: 48402

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEEEGQPIDLVTF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHH
ISRVDPKFLEGIGGMEYFIGLMDGVPTTRNFSYYEGLVRGAWKMYQAGVLGHKMGERLIA
HHHCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNEEIIGETITALCELEEQDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLNKMT
HCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
CGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
CCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHC
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCE
ILMIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKR
EHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLSDLRETGQIEQDADVIMLMYREDYYDKETKQKEMTEIHVAKHRNGPVGSFKLRFMKE
HHHHHHHHCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FGRFVEGK
HHHHHCCC
>Mature Secondary Structure 
SIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEEEGQPIDLVTF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHH
ISRVDPKFLEGIGGMEYFIGLMDGVPTTRNFSYYEGLVRGAWKMYQAGVLGHKMGERLIA
HHHCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNEEIIGETITALCELEEQDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLNKMT
HCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
CGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
CCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHC
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCE
ILMIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKR
EHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLSDLRETGQIEQDADVIMLMYREDYYDKETKQKEMTEIHVAKHRNGPVGSFKLRFMKE
HHHHHHHHCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FGRFVEGK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]