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The map label for this gene is citT [H]

Identifier: 218902123

GI number: 218902123

Start: 972915

End: 973592

Strand: Direct

Name: citT [H]

Synonym: BCAH820_1005

Alternate gene names: 218902123

Gene position: 972915-973592 (Clockwise)

Preceding gene: 218902122

Following gene: 218902124

Centisome position: 18.35

GC content: 38.05

Gene sequence:

>678_bases
ATGTTGAAGGTTGCAATTGCAGAAGATGATTTCCGCGTCGCGCAAATTCAGGAAGAGTTTTTATTAAAAATAAAGGACGT
AAAAGTGATCGGAAAAGCATTAAACGCAAAAGAAACGATGGAACTACTACAAAGGGAAGAAATCGATTTGCTTCTATTAG
ATAATTATTTACCAGATGGAATTGGAACAGACTTATTGCCGAAAATCCATGCTGACTTTCCAAACGTTGATGTCATTATG
GTTACTGCGGCGAATGAAAACCATATGCTAGAAAAAGCAATTCGAAACGGCGTAAGCAACTACCTTATAAAACCGGTCAC
ATTAGAAAAGTTCGTTCGCACAATTGAAGACTATAAAAGAAAGAAGCAACTATTACATAGTAGCAATGAAGTAAATCAAG
CAATCATTGATAACTTTTTTGGCACTTCACAAACACAAGACATAAAAAACTTACCGACAGGTGTCGATCCGTTAACACTG
CAAAAAGTGAAAGGAATTATAAAAGGGTTCGACGAGGGCATTACAATAGAAGAAATGGGGGAGCAAATGGGGGCCTCCAG
AACAACCGCAAGAAGATATTTAGAATACTTAGTGGCGACAAACGAGTGCACAGTAGAATACACATACGGAATAATTGGAC
GACCAGAACGAAAATATCGAATAGGACGAGGGCTATGA

Upstream 100 bases:

>100_bases
ACAATTGAAATTCAAAACGAGAAAAATGGGGGAGCTATTTTTACAATTTACCTTCCAAAAACATTGAGAGAAAGTACATA
ACAAACAGGGGGATGGACAT

Downstream 100 bases:

>100_bases
AAAAACGATTATTACTATGTATATGGATCATGACAGGAGTAATAGTTGGTTGTTCCTCAGAAAAATCCCATACGAATAAA
GTGAACATCGACAAATTAGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVIGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPKIHADFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHSSNEVNQAIIDNFFGTSQTQDIKNLPTGVDPLTL
QKVKGIIKGFDEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL

Sequences:

>Translated_225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVIGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPKIHADFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHSSNEVNQAIIDNFFGTSQTQDIKNLPTGVDPLTL
QKVKGIIKGFDEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
>Mature_225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVIGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPKIHADFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHSSNEVNQAIIDNFFGTSQTQDIKNLPTGVDPLTL
QKVKGIIKGFDEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=223, Percent_Identity=36.7713004484305, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790566, Length=226, Percent_Identity=30.5309734513274, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25544; Mature: 25544

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVIGKALNAKETMELLQREEIDLLLLDNYLPDG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCC
IGTDLLPKIHADFPNVDVIMVTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKR
CCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHH
KKQLLHSSNEVNQAIIDNFFGTSQTQDIKNLPTGVDPLTLQKVKGIIKGFDEGITIEEMG
HHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
EQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
HHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCCC
>Mature Secondary Structure
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVIGKALNAKETMELLQREEIDLLLLDNYLPDG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCC
IGTDLLPKIHADFPNVDVIMVTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKR
CCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHH
KKQLLHSSNEVNQAIIDNFFGTSQTQDIKNLPTGVDPLTLQKVKGIIKGFDEGITIEEMG
HHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
EQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
HHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]