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The map label for this gene is yrkH [H]

Identifier: 218901989

GI number: 218901989

Start: 834372

End: 835502

Strand: Direct

Name: yrkH [H]

Synonym: BCAH820_0871

Alternate gene names: 218901989

Gene position: 834372-835502 (Clockwise)

Preceding gene: 218901988

Following gene: 218901990

Centisome position: 15.73

GC content: 36.07

Gene sequence:

>1131_bases
ATGGAAGTTAAATCATTACAAGCAAAAGATGTTGCAGAGAAAGTTTTATTCGGAGAGTTGTTTATTTTAGATGTTCGTAA
TGAGACGGATTATGAAGATTGGAAAATTGAAGGGAAACAAATCTCATCTATAAATAAACCGTATTTTGATTTGTTAGATG
GTGTAGATCAAATTGTAAGTGAATTACCTAAAGATAAAGATGTTTTAGTAGTATGTGCAAAAGAAGGGTCTTCTATATTT
GTGGCAGAGCAGTTAACAGAGGCTGGATTAGAAAATATTTATTATTTAGCTGGTGGTATGAAGGCTTGGAGTGAATATGT
AAAGCCTATAAAAGTTGGAGATTTAAAAAATGGCGGAAGTATGTACCAGTTTAACCGCCTTGGAAAAGGCTGTTTATCTT
ATATGGTCGTTTCAAACGGTGAAGCAGCAGTTATTGATGCAATAAGAACAGTTGAAGCGTATGAACAATTTGCGAAAGAG
AATGGCGTTACGATTACGAATGTAATGGATACACATTTACATGCAGACCATATTTCTGGAGGACGTAAGTTAGCTGAAAA
AGTAGGGGGGACGTACTGGTTACCACCAAAAGATGCGGAGGAAGTTGTTTTCTTATATGAACCGCTCGTTGAAGGATCTG
TTATTACGGTGGGGGGTACTAAAATTGAAATTGATGCATTATACTCACCGGGGCATACGATTGGAAGTACATCATTTATT
GTAGATAATTCCTATTTATTATCAGGCGATATTTTATTTGTAGATTCCATCGGGCGTCCAGATCTTGCTGGGAAGGCTGA
AGATTGGGTAAGTGATTTACGTAATACTTTGTATAGCCGATATAAAGAACTATCTCAAAGTTTAATTGTGTTACCGGCTC
ATTATTCAAAAATAAGTGAAATGGACGAAAGTGGTATTGTTAGTGCAAAATTAAAAGATTTATTTGAGCATAATGCAGGA
TTAAATATTGAGGATGAGGGAGAGTTCCGTAAAGTTGTAACAGAAAACTTACCACCTCAACCAAATGCATATGAAGAAAT
CCGTCAAACGAATATGGGTAAAATTCACCCGAGTGTGGATGAAGAGCGTGAAATGGAGATTGGTCCAAATCGTTGTGCAG
TTCACAAATAA

Upstream 100 bases:

>100_bases
ATACAAATGTGAAAAATGTTATTCCCGGTATGATAGAGTGGCAAGGGAATATAGAGAATTAAATTTTTTTAAATAAAAAT
ATACCTCAGGGGGTAAGAAG

Downstream 100 bases:

>100_bases
ATAAACGAATAAATGAATGAATGAAAAATGGAGGAATAGATGATGAATGTAAAACAAGTATTAGATGCGAAAGATTTAGC
ATGTCCAATGCCGATTGTAA

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MEVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDQIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFLYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
VDNSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK

Sequences:

>Translated_376_residues
MEVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDQIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFLYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
VDNSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK
>Mature_376_residues
MEVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDQIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFLYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
VDNSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=187, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI116642887, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330176, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41739; Mature: 41739

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDQIVS
CCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKENGVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFLYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDNSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHK
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEVKSLQAKDVAEKVLFGELFILDVRNETDYEDWKIEGKQISSINKPYFDLLDGVDQIVS
CCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKENGVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFLYEPLVEGSVITVGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDNSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQSLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHK
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]