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The map label for this gene is yqjI [H]

Identifier: 218901367

GI number: 218901367

Start: 165255

End: 166664

Strand: Direct

Name: yqjI [H]

Synonym: BCAH820_0186

Alternate gene names: 218901367

Gene position: 165255-166664 (Clockwise)

Preceding gene: 218901366

Following gene: 218901368

Centisome position: 3.12

GC content: 39.08

Gene sequence:

>1410_bases
ATGGAAAAGTTACAAATTGGAGTTGTTGGTGTGGGCGTTATGGGAAAAAGCCTCGCACTTAACTTTGAGAGTAAAGGGTA
TTCTGTTGCCCTATATGATATTTCAAAGGAAAAAGTTGATGAAACCATTGAGGAAAACCGTGGTAAAAACTTAGTTGGTA
CTCATATAGTTGAAGAGTTTGTTAACTCACTCGAATCACCTAGAAAGATTTTATTAATGGTTAATGCGGGGGAAATTACA
GATAAAGCGATTGATTCTCTAGTCCCTCACCTCGATAAAGGTGATATTTTAATTGATGGTGGTAATACATACTTTGTCGA
TACAATTCGCCGAAACAAACGTCTTGCCGAAGAAGGAATCAATTTCATCGGGGCAGGTGTGTCAGGCGGCGAAGAGGGTG
CATTGAAGGGACCATCTATTATGCCCGGCGGACAGAAGGATGCATACGAAAAAGTAAAGGATATGCTTGAAAACATCTCT
GCAAAAGTGAATAACGAGCCTTGCTGTTCTTATATCGGACCTAATGGGGCAGGACACTATGTAAAGATGGTTCACAATGG
TATTGAGTATGGAGATATGCAATTAATTTGTGAAGCATATTTCTTCTTGAAACAAACACTAGATTTGACTGCAGAAGAGT
TCCATGAAATATTTGCTGAATGGAATAAAGGTGAACTGAACAGCTATCTAATTGAGATTACAGCCGATATTTTCAAGAAG
AAAGATGAAGAAACTGGTAAGCCATTAGTGGATGTTATTCTTGATACTGCAGGACAAAAGGGTACAGGGAAATGGACAAG
TCAAAGCGCACTTGATTTAGGTATCTCTCTGCCTATTATCACGGAATCTGTATTTGCACGTTGCATTTCTGCTTTAAAAG
AAGAGCGTGTGAACGCAAGCAAAGTTTTATCTGGCCCTAAAGATAAAACAGCAATTGGAGTTGAAAAAGCCGAATTAATT
GAAGCGGTGCGCCAAGCTTTATATATGAGTAAAATTTGTTCTTATGCACAAGGATTCACGCAATTGAAGGCAGCTTCTGA
GGAATATGATTGGAACCTTGATTTTGGCAGCATTTCTATGCTTTGGAGAGGCGGATGTATTATCCGTGCTGCCTTTTTAC
AGAACATTAAAGAGGCTTATGAGACTAACACTGACCTACCGAACCTTTTACTTGATCCATACTTTAAAGAAATTGTAGAG
TCATATCAAGGTGGATTACGCCAAATTATCTCAATGGCGGTACAACAGGGCATTCCGATACCTGCATTTTCAGCAGCAAT
TTCTTATTATGACAGCTATCGTACTGCCAAACTACCTGCAAACTTATTGCAAGCGCAGCGCGATTATTTTGGAGCGCATA
CGTATAAACGAGTAGATAAAGAAGGTACATTCCATACAAAATGGATATAA

Upstream 100 bases:

>100_bases
AGCCTATTGAAATGAAAAAGTTGGATTATTTGATTAAAATGTTATTTTAGGTATATATACTATAATACAGAGTAACATAC
ATGGAAAGGAACGATAGAAT

Downstream 100 bases:

>100_bases
AATAATAAATGGACTAAGATTAAATTCTTAGTCCATTTTTCATTCCACAATTCGTAGGCTATAAGACTCCCACTGATGGA
AGTTCACTTTAAACGAATGT

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEFVNSLESPRKILLMVNAGEIT
DKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGINFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENIS
AKVNNEPCCSYIGPNGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFAEWNKGELNSYLIEITADIFKK
KDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNASKVLSGPKDKTAIGVEKAELI
EAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISMLWRGGCIIRAAFLQNIKEAYETNTDLPNLLLDPYFKEIVE
SYQGGLRQIISMAVQQGIPIPAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI

Sequences:

>Translated_469_residues
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEFVNSLESPRKILLMVNAGEIT
DKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGINFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENIS
AKVNNEPCCSYIGPNGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFAEWNKGELNSYLIEITADIFKK
KDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNASKVLSGPKDKTAIGVEKAELI
EAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISMLWRGGCIIRAAFLQNIKEAYETNTDLPNLLLDPYFKEIVE
SYQGGLRQIISMAVQQGIPIPAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI
>Mature_469_residues
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEFVNSLESPRKILLMVNAGEIT
DKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGINFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENIS
AKVNNEPCCSYIGPNGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFAEWNKGELNSYLIEITADIFKK
KDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNASKVLSGPKDKTAIGVEKAELI
EAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISMLWRGGCIIRAAFLQNIKEAYETNTDLPNLLLDPYFKEIVE
SYQGGLRQIISMAVQQGIPIPAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=471, Percent_Identity=52.0169851380042, Blast_Score=485, Evalue=1e-137,
Organism=Escherichia coli, GI1788341, Length=470, Percent_Identity=67.2340425531915, Blast_Score=650, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17542558, Length=471, Percent_Identity=50.3184713375796, Blast_Score=510, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6321695, Length=461, Percent_Identity=52.060737527115, Blast_Score=511, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6321977, Length=452, Percent_Identity=52.6548672566372, Blast_Score=486, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24639279, Length=466, Percent_Identity=51.7167381974249, Blast_Score=476, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 51900; Mature: 51900

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEF
CCCEEEEEEEECCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
VNSLESPRKILLMVNAGEITDKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGI
HHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHHCC
NFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENISAKVNNEPCCSYIGPNGAGHY
CEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
VKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFAEWNKGELNSYLIEITADIFKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
KDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNAS
CCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
KVLSGPKDKTAIGVEKAELIEAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISM
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LWRGGCIIRAAFLQNIKEAYETNTDLPNLLLDPYFKEIVESYQGGLRQIISMAVQQGIPI
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI
CHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEF
CCCEEEEEEEECCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHH
VNSLESPRKILLMVNAGEITDKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGI
HHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHHCC
NFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENISAKVNNEPCCSYIGPNGAGHY
CEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
VKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFAEWNKGELNSYLIEITADIFKK
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
KDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNAS
CCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
KVLSGPKDKTAIGVEKAELIEAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISM
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LWRGGCIIRAAFLQNIKEAYETNTDLPNLLLDPYFKEIVESYQGGLRQIISMAVQQGIPI
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI
CHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]