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The map label for this gene is gntK [H]

Identifier: 218901365

GI number: 218901365

Start: 161989

End: 163524

Strand: Direct

Name: gntK [H]

Synonym: BCAH820_0184

Alternate gene names: 218901365

Gene position: 161989-163524 (Clockwise)

Preceding gene: 218901364

Following gene: 218901366

Centisome position: 3.05

GC content: 38.74

Gene sequence:

>1536_bases
ATGAGTAGCTATATGTTAGGTATAGATATCGGTACAACAAGTACGAAAGCAGTTTTATTTACTGAAAAAGGCGAAGTCAT
TCAAACCGAGAATATTGGTTATCCACTTCGCACACCGGATATATCCACAGCGGAACAAGATCCAGAAGAGATTTTCCAAG
CTGTTTTACAAGCGATATCAAATATAACGAAACAGCATTCAGATAAAAAACCATCGTTTATTTCATTTAGCAGTGCTATG
CATAGTGTCATTGCTATGGATGAAAATGATCAGCCGCTGACACCTTGTATCACTTGGGCAGATAATCGCAGTGAGGCATG
GGCGCATAAAATCAAAGATGAACTGAATGGCCATGCAGTTTATAGACGAACAGGAACACCTATTCACCCAATGTCACCAT
TAAGTAAAATTACATGGATTGTGAATGCCCATCCGGAAATTGCTATTAGAACGAAAAAATATATTGGAATCAAAGAATAT
ATCTTCAAAAAATTCTTTGATCAATATGTTGTTGATCATTCCATCGCCTCGTGCATGGGTATGATGAACTTAAAAACGCT
AGATTGGGATGAGGAAGCTTTAAAAATTGCTGGTATAACATCAGCTCAATTATCTAAACTCGTACCAACCACCAAAATAT
TCAGCAACTGCAATCCAGATTTAGCCCAAAAGATTGGTATCGATTCCCAAACACCGTTTGTCATTGGTGCCAGTGATGGG
GTGCTTTCTAATCTAGGTGTGAATGCAATTCGGAAAGGGGAGATTGCTGTCACAATTGGAACAAGTGGTGCTATTCGGAC
CATTATTGATAAACCACAAACAGATAAAAAAGGAAGAATATTTTGTTATGCCTTAACCGAAAAGCATTGGGTAATTGGTG
GACCGGTAAACAATGGAGGGATGGTCCTTCGCTGGATTCGTGATGAACTTGCTTCATCAGAAGTAGAAACTGCGAAAAGA
CTAGGAATTGATCCATACGATGTATTAACTAAAATAGCAGAACGCGTGAGACCTGGTGCAGACGGATTATTATTCCATCC
ATACCTCGCAGGGGAACGTGCACCATTATGGAATCCAGATGTACGTGGCTCCTTCTTTGGTTTAACGATGTCACATAAGA
AGGAACATATGATTCGTGCAGCTTTAGAGGGTGTTATATATAATTTATACACTGTATTTTTAGCATTAACAGAATGTATG
GATGGTCCTGTAACTCGTATTCAAGCAACAGGCGGCTTCGCAAGGTCTGACGTTTGGCGACAGATGATGTCCGATATTTT
CGCATCTGAAGTCGTTGTTCCAAAGAGCTACGAAAGCTCTTGTCTAGGTGCATGTATATTAGGTCTCTATGCCACAGGAA
AAATTGATTCTTTTGAAATCGTTTCCGAAATGGTTGGTAGTACCTACAAACATACACCGAAAGAAGAAGCAACAAAAGAA
TACAGACAATTACTGCCTATATTTATTAACCTATCAAGGGCGTTAGAAGATGATTATACACGCATTGCAAATTATCAAAG
AAATTTAATAAAGTAA

Upstream 100 bases:

>100_bases
ATGATTGAGGCCTTACATCAAAACTTTGATGATGTTCAAGGGAAAGTCGAAGACCTCTGGATGTCACAACAAATGTTATC
TAAAGGAGTTGAGCAAGGAC

Downstream 100 bases:

>100_bases
AACTTTCATCAGTAACCTCCCACGCCTCGCTTCTATCTAAATCTCGAGGTGATGGGGGCCTTACTGCCCACGAATAGCGG
GATAAATACAAATACAGCTA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAM
HSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEY
IFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDG
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
YRQLLPIFINLSRALEDDYTRIANYQRNLIK

Sequences:

>Translated_511_residues
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAM
HSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEY
IFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDG
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
>Mature_510_residues
SSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAMH
SVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYI
FKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDGV
LSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRL
GIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMD
GPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEY
RQLLPIFINLSRALEDDYTRIANYQRNLIK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=473, Percent_Identity=22.4101479915433, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI189409120, Length=469, Percent_Identity=22.8144989339019, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4504007, Length=469, Percent_Identity=22.8144989339019, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=22.0982142857143, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI18860918, Length=421, Percent_Identity=22.3277909738717, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI88196792, Length=326, Percent_Identity=25.7668711656442, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789987, Length=499, Percent_Identity=26.6533066132265, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=25.147347740668, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=25.3036437246964, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790005, Length=521, Percent_Identity=23.8003838771593, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=20.5821205821206, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789138, Length=510, Percent_Identity=23.1372549019608, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=463, Percent_Identity=23.110151187905, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321755, Length=418, Percent_Identity=25.1196172248804, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=24.4210526315789, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24654573, Length=399, Percent_Identity=24.812030075188, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655555, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655560, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655570, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655574, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655565, Length=472, Percent_Identity=23.5169491525424, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656367, Length=486, Percent_Identity=21.1934156378601, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357867, Length=498, Percent_Identity=22.289156626506, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656372, Length=302, Percent_Identity=24.1721854304636, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56858; Mature: 56727

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAIS
CCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NITKQHSDKKPSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAV
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEE
YRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKKFFDQYVVDHSIASCMG
EEECCCCCCCCCCHHHEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDG
HCCCEECCCCHHHHEEECCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEEECCCC
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
MVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAIS
CCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NITKQHSDKKPSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAV
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEE
YRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKKFFDQYVVDHSIASCMG
EEECCCCCCCCCCHHHEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDG
HCCCEECCCCHHHHEEECCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEEECCCC
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
MVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]