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The map label for this gene is rocF [H]

Identifier: 218901358

GI number: 218901358

Start: 152621

End: 153514

Strand: Direct

Name: rocF [H]

Synonym: BCAH820_0177

Alternate gene names: 218901358

Gene position: 152621-153514 (Clockwise)

Preceding gene: 218901357

Following gene: 218901359

Centisome position: 2.88

GC content: 38.14

Gene sequence:

>894_bases
ATGAAAAAAGAAATTTCGGTTATTGGAGTTCCAATGGATTTAGGGCAGATGCGTCGTGGAGTTGATATGGGACCGAGCGC
AATCCGTTATGCAGGTGTAATTGAAAGAATTGAAGAAATTGGATATGACGTTAAAGATATGGGAGATATATGTATAGAGA
GAGAAAAAGAAGTAGATGTAAATACAAGCTTAAGAAACCTTACACAAGTTGCAACTGTATGTAACGAATTAGCAAGTAAG
GTAGATCATATTATAGAAGAAGGGCGTTTTCCACTTGTATTAGGTGGCGATCATAGTATCGCTATTGGTACATTAGCTGG
TGTGGCGAAACATTATAAAAACCTAGGTGTTATTTGGTACGATGCACATGGTGATTTAAATACAGAAGAAACTTCACCAT
CTGGGAATATTCACGGTATGTCACTTGCAGCAAGTTTAGGGTATGGACATCCCACGCTTGTAGATTTATACGGGGCATAT
CCAAAGGTGAAAAAAGAGAATGTTGTCATTATCGGTGCACGTGCATTAGATGAAGGAGAAAAAGACTTTATTCGCAATGA
AGGTATTAAAGTATTCACAATGCACGAGATTGATCGTATGGGTATGACAGCTGTTATGGAAGAAACAATTGAATATTTAT
CTCATACTGACGGTGTGCATTTATCATTAGATTTAGATGGTCTTGATCCTCATGATGCACCAGGAGTTGGAACACCTGTA
ATTGGTGGCCTATCTTATCGTGAGAGCCATTTAGCAATGGAGATGTTAGCGGAAGCTGATATTGTTACATCTGCGGAGTT
TGTTGAGGTAAATACGATTTTAGATGAGCGAAATAGAACGGCAACAACAGCGGTTGCTTTAATGGGTTCTTTATTCGGTG
AAAAACTAAAATAA

Upstream 100 bases:

>100_bases
GTGAATAATTTGTATATCCATACAGAAAAATGTCGAGTTGAGTCAGACTATATAAAAGATTTAAAATATTTAGTGAAGGC
ACAGAAGGGGGATACTATCT

Downstream 100 bases:

>100_bases
ATGTAAGAAAAGCAACTGAGAAGTTGCTTTTTTTATTTGAAAATAGGCGTATAATAATGATTTATATTATACTGTACGAT
AAGAATGTTTGACATCTTAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK

Sequences:

>Translated_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
>Mature_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDVNTSLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=300, Percent_Identity=40.3333333333333, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI4502215, Length=300, Percent_Identity=38.6666666666667, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI37537722, Length=292, Percent_Identity=27.7397260273973, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1789306, Length=278, Percent_Identity=25.8992805755396, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996843, Length=236, Percent_Identity=36.4406779661017, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6325146, Length=320, Percent_Identity=30.9375, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24638886, Length=310, Percent_Identity=30.9677419354839, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32308; Mature: 32308

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDV
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTSLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHCCCCCCCCCCEEEEEEHHCCCCC
KDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEVDV
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTSLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHPTLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHCCCCCCCCCCEEEEEEHHCCCCC
KDFIRNEGIKVFTMHEIDRMGMTAVMEETIEYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIVTSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]