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The map label for this gene is rgy2 [H]

Identifier: 218884544

GI number: 218884544

Start: 1152005

End: 1155643

Strand: Direct

Name: rgy2 [H]

Synonym: DKAM_1233

Alternate gene names: 218884544

Gene position: 1152005-1155643 (Clockwise)

Preceding gene: 218884540

Following gene: 218884547

Centisome position: 84.38

GC content: 46.83

Gene sequence:

>3639_bases
TTGCCTGGTGCCTTTAACCCTTTATATAAGGGTTTCTGCCCAGTATGTGGCGGAGATATCTTGTCAAGCGAAGTAGAGTT
ACGTGGTTTCTGTAGCAGGTGTGCTAATAGTGGTTTAACGAGTATACTCAGGGATATTGCATCCAGTGGACTGGGCGATT
TCGAGGAGTTCTTCAGGAGGGCTAGTAACGGGCTTAGTGTATGGGGGGCTCAGAAGATCTGGGCTAAGAGGCTTGTCTCC
GGGGAGAACACTGTGTTGATCGCGCCAACTGGTATGGGTAAGACAACACTACTGATCATTTACTCGCTTTACGCGGCTAG
GAGAGGCAAGAGAGTTGTCTATATAACACCAACGAGAACCCTCTTAACCCAGATCCATCGTAGACTAGTGGAGGCAGCTG
AAAGGACCGGGATTAATGGGGTCAACTTGATCGCTTATGATTCATCCATGAGTAAGAAGAAAAGGGAGGAGGTATTATCT
AGGATTGAAAAAGGAGAGTATAGCATACTCGTCGCAACAAACGGCTTCCTATCGAGGAAGTCCGAGCTGCTTTCAAGGAG
TAGACCAGATATAGTGATAGCTGACGATGTTGACAGCGTAGTGAGGAGTGAGAAGAATGTACTGAGGCTACTGAGGATAC
TGGGCTATAGTGATGAAGTCATCGAGCTGGCTAAGAAGAGGATTAGCCTTCTCTGGAGGCTAATGGTTAACAAGGCCTTC
AACAACAACGATAAGTACGCTGAATTAGTAAAGGAGTACATAGAGGTGGACTCGCTCATCGAGAAAACACTCTCTAGTAC
ACGCCACGCGCAATTCATCGTTGCATCAGCCACCGGCCGTATGAAAGGCTTAATGGGCAGGATCCTTAAGGAGCTACTCC
ATGTTGATATATCAGGCGTGACCATCTACGGGAGAGACGTCACCGATGCATACATGCTGATTAAACCAGGCGAGCTACAT
GGGGAGCTGGTCAGGATCATTGAGAAACTGGGTCCAGGAGGAATAATATATATAGCGCCACACCACCCGTTTAAGAACAT
GCTCAAGGAGGAATTAGATAAGGCTGTGAACATTCTAGCAGATAAAGGATTCAGAATAGGGGATGCAACACCGGGTAATG
TAGCAAGGCTGATCAAGGGGGAGCTCGACATACTAACCGGTTCGGCAAGCTATTATGGGTCAAGCGTTAGAGGCATCGAT
GCCCCGGAGGCTATAAGGTATGTTGTATTCATCGGATCCCCGGTTTTCGCCACCAGCCTAGAGTCACTCCTAGCCAACCC
AGGCATGATGATCCGTGTACTCCTTGAACTGGTTGACAGCAACGATGCCCGAAACAGAGTGTTAGAGTTAAGGAGGCTCC
TCTACACGTTGACCCCTGGCGAGGTGAGACTTGTTAAGCTGGCCTTAACTGGTAAAATACTCGAGGAGGCCCTGCAGGCC
AGTGAGAAGCTTTATTCAAAGTACCAGGTGATAAAGCAGTATTACAGGGAAACACTGGAGAGAACCAGGTCTATCCTGGA
TGAGAAGGGGATCATGGATATTGGTACCTTAACACTGGTGAGAGCTGGCGGCGACTACTACGCCTTAATACCAGATGTAA
TGACATATATACAGGCTAGCGGTAGAACAAGTAGGTTATATGGCTCCAGGATGACCCATGGGCTCTCAATAGTATTTGAG
TACAGGGCCCTCTACAACACTGTAAAAGGCCTTGAAGCCAGGCTGAAGGGCTTGAACAAGGAGCTGGTGTTCATAGACCT
AGCCAGTGTCGACCTAGACTCTGAGATCAAGGCGATTGAATCGAGCAGGAGGAATAATGATTCCTCCCCTGGGATGAGTT
ACAGGTCTATCCTAGTGGTAGTAGAGTCACCAACCAAGGCTAAGACGATAGCTAGATTCTTCGGTAAACCGGTTGCCAGG
AAGCTCGGCGATGTAACCGTCTACGAGATCCCTGTTAAAATAGGTGGGGAAATAATTCACTTAAACATAGTACCAACCCG
TGGACACATCTTCGATCTAACAACTGGCGAGGAGGGATACTATGGTGTTGTCATCGCTGATAACAGGGTTACACCAGTAT
ACGAGTACATAAAGAAGTGTAGGTTATGTGGGACACAGTTCACCACAGGCGATCACTGTCCAAGATGCGGTAGCAGGTTA
TTCAGTGATTCAAGGACAATTGTAGCCGCTTTGAGAAAGATAGCCGGCGAGGTCGATGAGGTATATATAGCGACCGATCC
CGATATTGAAGGTGAAAAGATAGCTTACGACGTCTACTTAGCCGTAAAGTATTATAATGAGAAAGTATGGAGGATAGAGC
TACATGAGATAACACTACAGGAGTTCCTTAAAGCCATTAACAACAAGAGGGGTATTAATCAACGACTAGTCGAGGGCGAG
ATATACAGGAGAGTACTCGATAGGCTGGTTGGATTCAAGCTGAGCCAGGAGTTACAGGGTATATATGGATTAAGGTTCCT
TGGTGCAGGCAGGGTTCAAACACCGACACTGGGGCTCGTGATAGATAGGTACGAGGAGTACATGAGAAACAAGTGTAAGA
AGATACGGTTTAAGCTTGGCTCACCATTGAACATCATCTACAGTGTTTTCATGGGGAAGAATTCAGAGGTAATCAGGGAG
TTGAAGACGGCCAAGATGCTTAAACTGGTTAGGGTAGGTAGGGAGATAGTTACTATAACGCCTAAACCACCGTATACAAC
AGACGAGCTCCTAAGCGACGCCGCCAAACTGAATCTACACACTGGTATAGTGATGAGTATCGCTCAGCAATTATTCGAAG
CTGGACTAATAACCTACCACAGGACTGATAGTCACTATGTAAGTAATACAGGCATAGGCATCGCGATGAAGTATATCGAG
GGGAAGAAGCTGGAGGACTACGCACGGCCAAGCCACTGGGGCTCGCCGGGCACGCATGAAGCAATAAGGCCTGTCTACCC
CTACGATCTCGACGACTTGTTGAAGGCTGTATCTGAGGGGGTGATTAACACCGTGATACCTTTAACAGGGATGCACTTAA
AGCTCTACGACCTAATATTCAAGCGGTTCATCTCAAGCCAGCTGAAGCCGTTTAAAGCCGTTAAATCTATTTACGCAGTA
TACTTCGGCGAGTTTAAACTCGGCGAGATAGAGTTGCTAACCAACATAGTTGAGGAGGGCTTCAACGTCTTCGAGAAAAC
CAGAGTTTACAAGGAGCTGGATGCCGTGGAATCTATTGAAGTCCCCGTGGAAGAGATATCCGTGGTGGATTCAAGTAAAT
CGCCGCTCTTCACTGAGGGTGAATTAGTTTCATTGATGAAGAAACTAGGCCTTGGAAGGCCAAGCACCTACTCGAAGATA
ATTGAGAGCATTAAAAGGCATGGCTATGTATTCGTCTCGAAGAAGAGACTAAAGCTTATTCCATCTAAGAGAGGAATAGA
GGTCTATGGGTATCTCAGGGATAGATACCCCGAACTAGTATCTATTGAGGCCACGCGAAGGCTCGAGGAATCAATAGATA
AGATAATCAATGGTGAAGTAGATGCATTGGTTTACCTTACTGACATAGGGTCCAGGCTAAACATGTTTCATTCAATCAAC
ATGGTTAATAGAGGCGACTTCGCTAGTACTTCCTCCTGA

Upstream 100 bases:

>100_bases
TACGTACCCTATTTTCACAAATACGAATAAATATCGTAGTACCGGTTCCCCTGTTTTTAAATCCATCATGTTGAAGCCAT
TGATCTAGTGAGGGATTGAT

Downstream 100 bases:

>100_bases
TCTCGATAACTATATAGGGTTTAATCCTACCGCGAACCTTCTCACTCCCGATCCCTATGTTGACGAGCTCGATACTGCTC
CCCATCCTGGAGACAAGCAT

Product: Reverse gyrase

Products: NA

Alternate protein names: Helicase; Topoisomerase [H]

Number of amino acids: Translated: 1212; Mature: 1211

Protein sequence:

>1212_residues
MPGAFNPLYKGFCPVCGGDILSSEVELRGFCSRCANSGLTSILRDIASSGLGDFEEFFRRASNGLSVWGAQKIWAKRLVS
GENTVLIAPTGMGKTTLLIIYSLYAARRGKRVVYITPTRTLLTQIHRRLVEAAERTGINGVNLIAYDSSMSKKKREEVLS
RIEKGEYSILVATNGFLSRKSELLSRSRPDIVIADDVDSVVRSEKNVLRLLRILGYSDEVIELAKKRISLLWRLMVNKAF
NNNDKYAELVKEYIEVDSLIEKTLSSTRHAQFIVASATGRMKGLMGRILKELLHVDISGVTIYGRDVTDAYMLIKPGELH
GELVRIIEKLGPGGIIYIAPHHPFKNMLKEELDKAVNILADKGFRIGDATPGNVARLIKGELDILTGSASYYGSSVRGID
APEAIRYVVFIGSPVFATSLESLLANPGMMIRVLLELVDSNDARNRVLELRRLLYTLTPGEVRLVKLALTGKILEEALQA
SEKLYSKYQVIKQYYRETLERTRSILDEKGIMDIGTLTLVRAGGDYYALIPDVMTYIQASGRTSRLYGSRMTHGLSIVFE
YRALYNTVKGLEARLKGLNKELVFIDLASVDLDSEIKAIESSRRNNDSSPGMSYRSILVVVESPTKAKTIARFFGKPVAR
KLGDVTVYEIPVKIGGEIIHLNIVPTRGHIFDLTTGEEGYYGVVIADNRVTPVYEYIKKCRLCGTQFTTGDHCPRCGSRL
FSDSRTIVAALRKIAGEVDEVYIATDPDIEGEKIAYDVYLAVKYYNEKVWRIELHEITLQEFLKAINNKRGINQRLVEGE
IYRRVLDRLVGFKLSQELQGIYGLRFLGAGRVQTPTLGLVIDRYEEYMRNKCKKIRFKLGSPLNIIYSVFMGKNSEVIRE
LKTAKMLKLVRVGREIVTITPKPPYTTDELLSDAAKLNLHTGIVMSIAQQLFEAGLITYHRTDSHYVSNTGIGIAMKYIE
GKKLEDYARPSHWGSPGTHEAIRPVYPYDLDDLLKAVSEGVINTVIPLTGMHLKLYDLIFKRFISSQLKPFKAVKSIYAV
YFGEFKLGEIELLTNIVEEGFNVFEKTRVYKELDAVESIEVPVEEISVVDSSKSPLFTEGELVSLMKKLGLGRPSTYSKI
IESIKRHGYVFVSKKRLKLIPSKRGIEVYGYLRDRYPELVSIEATRRLEESIDKIINGEVDALVYLTDIGSRLNMFHSIN
MVNRGDFASTSS

Sequences:

>Translated_1212_residues
MPGAFNPLYKGFCPVCGGDILSSEVELRGFCSRCANSGLTSILRDIASSGLGDFEEFFRRASNGLSVWGAQKIWAKRLVS
GENTVLIAPTGMGKTTLLIIYSLYAARRGKRVVYITPTRTLLTQIHRRLVEAAERTGINGVNLIAYDSSMSKKKREEVLS
RIEKGEYSILVATNGFLSRKSELLSRSRPDIVIADDVDSVVRSEKNVLRLLRILGYSDEVIELAKKRISLLWRLMVNKAF
NNNDKYAELVKEYIEVDSLIEKTLSSTRHAQFIVASATGRMKGLMGRILKELLHVDISGVTIYGRDVTDAYMLIKPGELH
GELVRIIEKLGPGGIIYIAPHHPFKNMLKEELDKAVNILADKGFRIGDATPGNVARLIKGELDILTGSASYYGSSVRGID
APEAIRYVVFIGSPVFATSLESLLANPGMMIRVLLELVDSNDARNRVLELRRLLYTLTPGEVRLVKLALTGKILEEALQA
SEKLYSKYQVIKQYYRETLERTRSILDEKGIMDIGTLTLVRAGGDYYALIPDVMTYIQASGRTSRLYGSRMTHGLSIVFE
YRALYNTVKGLEARLKGLNKELVFIDLASVDLDSEIKAIESSRRNNDSSPGMSYRSILVVVESPTKAKTIARFFGKPVAR
KLGDVTVYEIPVKIGGEIIHLNIVPTRGHIFDLTTGEEGYYGVVIADNRVTPVYEYIKKCRLCGTQFTTGDHCPRCGSRL
FSDSRTIVAALRKIAGEVDEVYIATDPDIEGEKIAYDVYLAVKYYNEKVWRIELHEITLQEFLKAINNKRGINQRLVEGE
IYRRVLDRLVGFKLSQELQGIYGLRFLGAGRVQTPTLGLVIDRYEEYMRNKCKKIRFKLGSPLNIIYSVFMGKNSEVIRE
LKTAKMLKLVRVGREIVTITPKPPYTTDELLSDAAKLNLHTGIVMSIAQQLFEAGLITYHRTDSHYVSNTGIGIAMKYIE
GKKLEDYARPSHWGSPGTHEAIRPVYPYDLDDLLKAVSEGVINTVIPLTGMHLKLYDLIFKRFISSQLKPFKAVKSIYAV
YFGEFKLGEIELLTNIVEEGFNVFEKTRVYKELDAVESIEVPVEEISVVDSSKSPLFTEGELVSLMKKLGLGRPSTYSKI
IESIKRHGYVFVSKKRLKLIPSKRGIEVYGYLRDRYPELVSIEATRRLEESIDKIINGEVDALVYLTDIGSRLNMFHSIN
MVNRGDFASTSS
>Mature_1211_residues
PGAFNPLYKGFCPVCGGDILSSEVELRGFCSRCANSGLTSILRDIASSGLGDFEEFFRRASNGLSVWGAQKIWAKRLVSG
ENTVLIAPTGMGKTTLLIIYSLYAARRGKRVVYITPTRTLLTQIHRRLVEAAERTGINGVNLIAYDSSMSKKKREEVLSR
IEKGEYSILVATNGFLSRKSELLSRSRPDIVIADDVDSVVRSEKNVLRLLRILGYSDEVIELAKKRISLLWRLMVNKAFN
NNDKYAELVKEYIEVDSLIEKTLSSTRHAQFIVASATGRMKGLMGRILKELLHVDISGVTIYGRDVTDAYMLIKPGELHG
ELVRIIEKLGPGGIIYIAPHHPFKNMLKEELDKAVNILADKGFRIGDATPGNVARLIKGELDILTGSASYYGSSVRGIDA
PEAIRYVVFIGSPVFATSLESLLANPGMMIRVLLELVDSNDARNRVLELRRLLYTLTPGEVRLVKLALTGKILEEALQAS
EKLYSKYQVIKQYYRETLERTRSILDEKGIMDIGTLTLVRAGGDYYALIPDVMTYIQASGRTSRLYGSRMTHGLSIVFEY
RALYNTVKGLEARLKGLNKELVFIDLASVDLDSEIKAIESSRRNNDSSPGMSYRSILVVVESPTKAKTIARFFGKPVARK
LGDVTVYEIPVKIGGEIIHLNIVPTRGHIFDLTTGEEGYYGVVIADNRVTPVYEYIKKCRLCGTQFTTGDHCPRCGSRLF
SDSRTIVAALRKIAGEVDEVYIATDPDIEGEKIAYDVYLAVKYYNEKVWRIELHEITLQEFLKAINNKRGINQRLVEGEI
YRRVLDRLVGFKLSQELQGIYGLRFLGAGRVQTPTLGLVIDRYEEYMRNKCKKIRFKLGSPLNIIYSVFMGKNSEVIREL
KTAKMLKLVRVGREIVTITPKPPYTTDELLSDAAKLNLHTGIVMSIAQQLFEAGLITYHRTDSHYVSNTGIGIAMKYIEG
KKLEDYARPSHWGSPGTHEAIRPVYPYDLDDLLKAVSEGVINTVIPLTGMHLKLYDLIFKRFISSQLKPFKAVKSIYAVY
FGEFKLGEIELLTNIVEEGFNVFEKTRVYKELDAVESIEVPVEEISVVDSSKSPLFTEGELVSLMKKLGLGRPSTYSKII
ESIKRHGYVFVSKKRLKLIPSKRGIEVYGYLRDRYPELVSIEATRRLEESIDKIINGEVDALVYLTDIGSRLNMFHSINM
VNRGDFASTSS

Specific function: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DN

COG id: COG1110

COG function: function code L; Reverse gyrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Escherichia coli, GI1787529, Length=599, Percent_Identity=28.2136894824708, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI32563869, Length=622, Percent_Identity=23.7942122186495, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR005736
- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013826
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR006171 [H]

Pfam domain/function: PF00270 DEAD; PF01131 Topoisom_bac; PF01751 Toprim [H]

EC number: =3.6.4.12; =5.99.1.3 [H]

Molecular weight: Translated: 136087; Mature: 135956

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAFNPLYKGFCPVCGGDILSSEVELRGFCSRCANSGLTSILRDIASSGLGDFEEFFRR
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
ASNGLSVWGAQKIWAKRLVSGENTVLIAPTGMGKTTLLIIYSLYAARRGKRVVYITPTRT
HCCCCEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCHHH
LLTQIHRRLVEAAERTGINGVNLIAYDSSMSKKKREEVLSRIEKGEYSILVATNGFLSRK
HHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
SELLSRSRPDIVIADDVDSVVRSEKNVLRLLRILGYSDEVIELAKKRISLLWRLMVNKAF
HHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
NNNDKYAELVKEYIEVDSLIEKTLSSTRHAQFIVASATGRMKGLMGRILKELLHVDISGV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCE
TIYGRDVTDAYMLIKPGELHGELVRIIEKLGPGGIIYIAPHHPFKNMLKEELDKAVNILA
EEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
DKGFRIGDATPGNVARLIKGELDILTGSASYYGSSVRGIDAPEAIRYVVFIGSPVFATSL
CCCEECCCCCCCHHHHHHHCCCEEEECCHHHCCCCCCCCCCHHHEEEEEEECCCHHHHHH
ESLLANPGMMIRVLLELVDSNDARNRVLELRRLLYTLTPGEVRLVKLALTGKILEEALQA
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
SEKLYSKYQVIKQYYRETLERTRSILDEKGIMDIGTLTLVRAGGDYYALIPDVMTYIQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCEEEEEECCCEEEHHHHHHHHHHCC
GRTSRLYGSRMTHGLSIVFEYRALYNTVKGLEARLKGLNKELVFIDLASVDLDSEIKAIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH
SSRRNNDSSPGMSYRSILVVVESPTKAKTIARFFGKPVARKLGDVTVYEIPVKIGGEIIH
HHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHCCHHHHHHCCCEEEEEEEEECCEEEE
LNIVPTRGHIFDLTTGEEGYYGVVIADNRVTPVYEYIKKCRLCGTQFTTGDHCPRCGSRL
EEEEECCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FSDSRTIVAALRKIAGEVDEVYIATDPDIEGEKIAYDVYLAVKYYNEKVWRIELHEITLQ
HCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEEEECCEEEEEEHHHHHHH
EFLKAINNKRGINQRLVEGEIYRRVLDRLVGFKLSQELQGIYGLRFLGAGRVQTPTLGLV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCHHHHH
IDRYEEYMRNKCKKIRFKLGSPLNIIYSVFMGKNSEVIRELKTAKMLKLVRVGREIVTIT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
PKPPYTTDELLSDAAKLNLHTGIVMSIAQQLFEAGLITYHRTDSHYVSNTGIGIAMKYIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCEEEEEECC
GKKLEDYARPSHWGSPGTHEAIRPVYPYDLDDLLKAVSEGVINTVIPLTGMHLKLYDLIF
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KRFISSQLKPFKAVKSIYAVYFGEFKLGEIELLTNIVEEGFNVFEKTRVYKELDAVESIE
HHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VPVEEISVVDSSKSPLFTEGELVSLMKKLGLGRPSTYSKIIESIKRHGYVFVSKKRLKLI
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCHHEEC
PSKRGIEVYGYLRDRYPELVSIEATRRLEESIDKIINGEVDALVYLTDIGSRLNMFHSIN
CCCCCEEEEEEHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCC
MVNRGDFASTSS
CCCCCCCCCCCC
>Mature Secondary Structure 
PGAFNPLYKGFCPVCGGDILSSEVELRGFCSRCANSGLTSILRDIASSGLGDFEEFFRR
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
ASNGLSVWGAQKIWAKRLVSGENTVLIAPTGMGKTTLLIIYSLYAARRGKRVVYITPTRT
HCCCCEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCHHH
LLTQIHRRLVEAAERTGINGVNLIAYDSSMSKKKREEVLSRIEKGEYSILVATNGFLSRK
HHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
SELLSRSRPDIVIADDVDSVVRSEKNVLRLLRILGYSDEVIELAKKRISLLWRLMVNKAF
HHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
NNNDKYAELVKEYIEVDSLIEKTLSSTRHAQFIVASATGRMKGLMGRILKELLHVDISGV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCE
TIYGRDVTDAYMLIKPGELHGELVRIIEKLGPGGIIYIAPHHPFKNMLKEELDKAVNILA
EEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
DKGFRIGDATPGNVARLIKGELDILTGSASYYGSSVRGIDAPEAIRYVVFIGSPVFATSL
CCCEECCCCCCCHHHHHHHCCCEEEECCHHHCCCCCCCCCCHHHEEEEEEECCCHHHHHH
ESLLANPGMMIRVLLELVDSNDARNRVLELRRLLYTLTPGEVRLVKLALTGKILEEALQA
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
SEKLYSKYQVIKQYYRETLERTRSILDEKGIMDIGTLTLVRAGGDYYALIPDVMTYIQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCEEEEEECCCEEEHHHHHHHHHHCC
GRTSRLYGSRMTHGLSIVFEYRALYNTVKGLEARLKGLNKELVFIDLASVDLDSEIKAIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHH
SSRRNNDSSPGMSYRSILVVVESPTKAKTIARFFGKPVARKLGDVTVYEIPVKIGGEIIH
HHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHCCHHHHHHCCCEEEEEEEEECCEEEE
LNIVPTRGHIFDLTTGEEGYYGVVIADNRVTPVYEYIKKCRLCGTQFTTGDHCPRCGSRL
EEEEECCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
FSDSRTIVAALRKIAGEVDEVYIATDPDIEGEKIAYDVYLAVKYYNEKVWRIELHEITLQ
HCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEEEECCEEEEEEHHHHHHH
EFLKAINNKRGINQRLVEGEIYRRVLDRLVGFKLSQELQGIYGLRFLGAGRVQTPTLGLV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCHHHHH
IDRYEEYMRNKCKKIRFKLGSPLNIIYSVFMGKNSEVIRELKTAKMLKLVRVGREIVTIT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
PKPPYTTDELLSDAAKLNLHTGIVMSIAQQLFEAGLITYHRTDSHYVSNTGIGIAMKYIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCEEEEEECC
GKKLEDYARPSHWGSPGTHEAIRPVYPYDLDDLLKAVSEGVINTVIPLTGMHLKLYDLIF
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KRFISSQLKPFKAVKSIYAVYFGEFKLGEIELLTNIVEEGFNVFEKTRVYKELDAVESIE
HHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VPVEEISVVDSSKSPLFTEGELVSLMKKLGLGRPSTYSKIIESIKRHGYVFVSKKRLKLI
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCHHEEC
PSKRGIEVYGYLRDRYPELVSIEATRRLEESIDKIINGEVDALVYLTDIGSRLNMFHSIN
CCCCCEEEEEEHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCC
MVNRGDFASTSS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]