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The map label for this gene is 218884321

Identifier: 218884321

GI number: 218884321

Start: 954983

End: 956152

Strand: Direct

Name: 218884321

Synonym: DKAM_1010

Alternate gene names: NA

Gene position: 954983-956152 (Clockwise)

Preceding gene: 218884319

Following gene: 218884326

Centisome position: 69.95

GC content: 49.15

Gene sequence:

>1170_bases
ATGCACTCCTTGCTTTACCCGTTTAAATTTATAAGCGCCAGATTCTTTAAGTCTATTGGCGACCCCTTAGCTCCCCGAGA
CCCATGGCTGGCCACGGGGAGGGAGCCGGGGAGGAACCGTGATAAACCACCCCACGAAGACCTAGAGCGTAGGTGGGAAA
CGGTTGAGGGGGTGTCATGCTTGGAGGAGATGTATAGGGGCTGGGTTAACCAGATTAGAGAGGCCCTGCTTGAATGGGGG
AGATACAGGGTTTCCGGGGTCTTCGACAAGATCGTGGTACTCGGTATGGGTGGTAGCGGTATAGTAGGGGATTTCCTAGC
TACTCTTTCACAAACCAGTAGAGGCCTCCCCGTGTATACTTCTAAATCGCATCACGCGCCTGGCTTCATTGACTCAGAGA
CACTGGTTTTATCAGTTAGTTACAGTGGTAATACTGTTGAAACAGTAAATGCAACTATCGAGGCGTTTAAGAAGACGGGG
AATATAGTGGTGGTCTCCAGCGGGGGTCATCTAAGAGACTATGCTTTGAAGCATGGATTACCATATATTCCACTACCCAC
GGGTCTTGCTCCAAGAGCCTCCCTGCCATCAATGCTCTTCAAGATCCTTGGATTACTTGACTCGAGCGGGTTATCCATGG
TGGGTAAGAGGGATGCTGAGGAAACCTTGTCATTCATAAATAGTGTCATGGATAACGCGGTGGAAGAGGCTTACCGGCTA
GCCGAGTGGATCCATGGAATCCAGGGTCTACTGGTTATTGCAACCCATACCCCTCTAGAAGCGCTGGCTCTAAGGGGTAA
GAACGAGTTTAATGAGAACAGTAAGATACCGGTTAAAATAGATGTTGCACCTGAATGGATGCATAACGATATAGTAGGGT
ATGAGGAGCCTAGTGGTATACCCTTAAAGATCATTGAAGTCTTCGACCCGGCTGACGAGGCTGGATGCAGGCTCGTGGAG
TTCATGGATGAAATATACAAGGAGGTTAATGCCTGGAGGCATAGGTTGAGTCTTAGAGGGGAGACATTATTAGATAAGCT
TATCTACGGTAGCCTAGTTCTCGGAGTGGCCAGCGTCAGGCTCGCGGTCCTCAGGGGTATAGATCCCCTTGAGACAAGGA
GTATCAAGAGGTATAAGGAGTCTGTGCATAATATATTCCCCGGGCTTTAA

Upstream 100 bases:

>100_bases
CTACCATCACGCTATAGTTATTTTATATCTCAACCCATTTAAAAGAAGAATAACTAGGTTGTATATCTGTTCCCAGTTTG
AAGGTTTTACAGGATGCTTA

Downstream 100 bases:

>100_bases
AGGTTAAAAAGCTCTAAGCACTATTAAACCTAGTATCTGAGGGGCCGTAGTCTAGCCTGGCTAGGATGCGGGGCTTGGGC
CCCCGTGACCCGGGGTTCAA

Product: bifunctional phosphoglucose/phosphomannose isomerase

Products: NA

Alternate protein names: Glucose-6-phosphate isomerase; GPI; Mannose-6-phosphate isomerase; Phosphoglucose isomerase; PGI; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MHSLLYPFKFISARFFKSIGDPLAPRDPWLATGREPGRNRDKPPHEDLERRWETVEGVSCLEEMYRGWVNQIREALLEWG
RYRVSGVFDKIVVLGMGGSGIVGDFLATLSQTSRGLPVYTSKSHHAPGFIDSETLVLSVSYSGNTVETVNATIEAFKKTG
NIVVVSSGGHLRDYALKHGLPYIPLPTGLAPRASLPSMLFKILGLLDSSGLSMVGKRDAEETLSFINSVMDNAVEEAYRL
AEWIHGIQGLLVIATHTPLEALALRGKNEFNENSKIPVKIDVAPEWMHNDIVGYEEPSGIPLKIIEVFDPADEAGCRLVE
FMDEIYKEVNAWRHRLSLRGETLLDKLIYGSLVLGVASVRLAVLRGIDPLETRSIKRYKESVHNIFPGL

Sequences:

>Translated_389_residues
MHSLLYPFKFISARFFKSIGDPLAPRDPWLATGREPGRNRDKPPHEDLERRWETVEGVSCLEEMYRGWVNQIREALLEWG
RYRVSGVFDKIVVLGMGGSGIVGDFLATLSQTSRGLPVYTSKSHHAPGFIDSETLVLSVSYSGNTVETVNATIEAFKKTG
NIVVVSSGGHLRDYALKHGLPYIPLPTGLAPRASLPSMLFKILGLLDSSGLSMVGKRDAEETLSFINSVMDNAVEEAYRL
AEWIHGIQGLLVIATHTPLEALALRGKNEFNENSKIPVKIDVAPEWMHNDIVGYEEPSGIPLKIIEVFDPADEAGCRLVE
FMDEIYKEVNAWRHRLSLRGETLLDKLIYGSLVLGVASVRLAVLRGIDPLETRSIKRYKESVHNIFPGL
>Mature_389_residues
MHSLLYPFKFISARFFKSIGDPLAPRDPWLATGREPGRNRDKPPHEDLERRWETVEGVSCLEEMYRGWVNQIREALLEWG
RYRVSGVFDKIVVLGMGGSGIVGDFLATLSQTSRGLPVYTSKSHHAPGFIDSETLVLSVSYSGNTVETVNATIEAFKKTG
NIVVVSSGGHLRDYALKHGLPYIPLPTGLAPRASLPSMLFKILGLLDSSGLSMVGKRDAEETLSFINSVMDNAVEEAYRL
AEWIHGIQGLLVIATHTPLEALALRGKNEFNENSKIPVKIDVAPEWMHNDIVGYEEPSGIPLKIIEVFDPADEAGCRLVE
FMDEIYKEVNAWRHRLSLRGETLLDKLIYGSLVLGVASVRLAVLRGIDPLETRSIKRYKESVHNIFPGL

Specific function: Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency [H]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011857
- InterPro:   IPR019490
- InterPro:   IPR001347 [H]

Pfam domain/function: PF10432 bact-PGI_C; PF01380 SIS [H]

EC number: =5.3.1.9; =5.3.1.8 [H]

Molecular weight: Translated: 43265; Mature: 43265

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLLYPFKFISARFFKSIGDPLAPRDPWLATGREPGRNRDKPPHEDLERRWETVEGVSC
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LEEMYRGWVNQIREALLEWGRYRVSGVFDKIVVLGMGGSGIVGDFLATLSQTSRGLPVYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEE
SKSHHAPGFIDSETLVLSVSYSGNTVETVNATIEAFKKTGNIVVVSSGGHLRDYALKHGL
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCC
PYIPLPTGLAPRASLPSMLFKILGLLDSSGLSMVGKRDAEETLSFINSVMDNAVEEAYRL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AEWIHGIQGLLVIATHTPLEALALRGKNEFNENSKIPVKIDVAPEWMHNDIVGYEEPSGI
HHHHHHHCCEEEEEECCCHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCCC
PLKIIEVFDPADEAGCRLVEFMDEIYKEVNAWRHRLSLRGETLLDKLIYGSLVLGVASVR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LAVLRGIDPLETRSIKRYKESVHNIFPGL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHSLLYPFKFISARFFKSIGDPLAPRDPWLATGREPGRNRDKPPHEDLERRWETVEGVSC
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LEEMYRGWVNQIREALLEWGRYRVSGVFDKIVVLGMGGSGIVGDFLATLSQTSRGLPVYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEE
SKSHHAPGFIDSETLVLSVSYSGNTVETVNATIEAFKKTGNIVVVSSGGHLRDYALKHGL
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCC
PYIPLPTGLAPRASLPSMLFKILGLLDSSGLSMVGKRDAEETLSFINSVMDNAVEEAYRL
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AEWIHGIQGLLVIATHTPLEALALRGKNEFNENSKIPVKIDVAPEWMHNDIVGYEEPSGI
HHHHHHHCCEEEEEECCCHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCCC
PLKIIEVFDPADEAGCRLVEFMDEIYKEVNAWRHRLSLRGETLLDKLIYGSLVLGVASVR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LAVLRGIDPLETRSIKRYKESVHNIFPGL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]