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The map label for this gene is sstT [H]

Identifier: 218884160

GI number: 218884160

Start: 816334

End: 817014

Strand: Reverse

Name: sstT [H]

Synonym: DKAM_0849

Alternate gene names: 218884160

Gene position: 817014-816334 (Counterclockwise)

Preceding gene: 218884162

Following gene: 218884159

Centisome position: 59.84

GC content: 46.99

Gene sequence:

>681_bases
TTGCTAGACTTCGTGCTATGGTATGGTCCCATAGGTGTCTTCGTGTTAATGGCGAATGTTGCCGCGGTAGTAGGAGTCCT
AGCTGTTTCCGCGTTCGCTAAGTTAATATTGTCATTCTATATAAGCGGCCTCATAATTCTACTGGTAATCCAACCACTAG
TACTTGGATTAGTTGCAAGAGTGAACCCGCTTAGATTCTGGAAGAAGTTCTACCCTGCAATGTTGACAGCCTTCTCCACT
GCAAGCAGTAACGCCACATTACCGGTCACTATAAGTTGCGCGATAAATGCTGGGATATCGAGGGATGTTGCAACAGTTAT
ACTACCTGTGGCAGCAACGATCAACATGCAGGGAGCCTGTGCGACTATCACATTATTCACCTTGTTCGCTTTCCAGGCAC
TTGGAATACCTATAGGATTCGGTGAAGTAATCACCTTGGTGGTCCTTGGATTTCTGGGTGCAACCGCGGCTGCTGGAGTG
CCCGGTGGAGCAGCCATAATTGCTATAGCTACTGCTACAACGCTAGGTATCCCAGTAGAGGCAGCTGGATGGATGGTTGG
TGTTCACCCAGCGGTAGATCCATTTGAGACCATGCTTAATGTAATAGGAGACCCTATAGGAGCCCTCATAGTTTCAAAGT
ACGTTACAAAAGACTTTGATGAAGGGAAGTGGAAACAGTAA

Upstream 100 bases:

>100_bases
ATAACCTTTTACTTAGAGAATGCTTCTTTGTGTATTCTTTCAATGTGTCACCATTTCTTGCTCAAATGCCTGCCCGGTTT
CTCTAGCGTGCATATACAAG

Downstream 100 bases:

>100_bases
TAATTTTTTCAATTTCTCTAACCTACTATACCCATAAATACTATAAAATCCCTCCAAGAAAAGACAATTATAGATGATAC
CCTACAACGAGAGATGATTA

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MLDFVLWYGPIGVFVLMANVAAVVGVLAVSAFAKLILSFYISGLIILLVIQPLVLGLVARVNPLRFWKKFYPAMLTAFST
ASSNATLPVTISCAINAGISRDVATVILPVAATINMQGACATITLFTLFAFQALGIPIGFGEVITLVVLGFLGATAAAGV
PGGAAIIAIATATTLGIPVEAAGWMVGVHPAVDPFETMLNVIGDPIGALIVSKYVTKDFDEGKWKQ

Sequences:

>Translated_226_residues
MLDFVLWYGPIGVFVLMANVAAVVGVLAVSAFAKLILSFYISGLIILLVIQPLVLGLVARVNPLRFWKKFYPAMLTAFST
ASSNATLPVTISCAINAGISRDVATVILPVAATINMQGACATITLFTLFAFQALGIPIGFGEVITLVVLGFLGATAAAGV
PGGAAIIAIATATTLGIPVEAAGWMVGVHPAVDPFETMLNVIGDPIGALIVSKYVTKDFDEGKWKQ
>Mature_226_residues
MLDFVLWYGPIGVFVLMANVAAVVGVLAVSAFAKLILSFYISGLIILLVIQPLVLGLVARVNPLRFWKKFYPAMLTAFST
ASSNATLPVTISCAINAGISRDVATVILPVAATINMQGACATITLFTLFAFQALGIPIGFGEVITLVVLGFLGATAAAGV
PGGAAIIAIATATTLGIPVEAAGWMVGVHPAVDPFETMLNVIGDPIGALIVSKYVTKDFDEGKWKQ

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI66773030, Length=225, Percent_Identity=32.8888888888889, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI194239697, Length=228, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI169790839, Length=227, Percent_Identity=32.15859030837, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI4827012, Length=224, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI223468564, Length=220, Percent_Identity=31.3636363636364, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI223468566, Length=220, Percent_Identity=31.3636363636364, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI5032093, Length=221, Percent_Identity=31.6742081447964, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40254478, Length=220, Percent_Identity=31.3636363636364, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI21314632, Length=233, Percent_Identity=30.4721030042918, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI262359914, Length=169, Percent_Identity=33.1360946745562, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI301601644, Length=163, Percent_Identity=28.2208588957055, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790514, Length=224, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789473, Length=211, Percent_Identity=33.175355450237, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789947, Length=230, Percent_Identity=26.5217391304348, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983106, Length=219, Percent_Identity=34.2465753424658, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71983099, Length=219, Percent_Identity=34.2465753424658, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17537407, Length=235, Percent_Identity=29.7872340425532, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193206505, Length=231, Percent_Identity=27.7056277056277, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71996953, Length=227, Percent_Identity=29.0748898678414, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17541374, Length=228, Percent_Identity=30.2631578947368, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193206654, Length=238, Percent_Identity=23.9495798319328, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583025, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137668, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24583023, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281360481, Length=223, Percent_Identity=30.0448430493274, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281360483, Length=223, Percent_Identity=30.0448430493274, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137666, Length=223, Percent_Identity=30.0448430493274, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 23482; Mature: 23482

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFVLWYGPIGVFVLMANVAAVVGVLAVSAFAKLILSFYISGLIILLVIQPLVLGLVAR
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPLRFWKKFYPAMLTAFSTASSNATLPVTISCAINAGISRDVATVILPVAATINMQGAC
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHH
ATITLFTLFAFQALGIPIGFGEVITLVVLGFLGATAAAGVPGGAAIIAIATATTLGIPVE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHHCCCCC
AAGWMVGVHPAVDPFETMLNVIGDPIGALIVSKYVTKDFDEGKWKQ
CCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLDFVLWYGPIGVFVLMANVAAVVGVLAVSAFAKLILSFYISGLIILLVIQPLVLGLVAR
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPLRFWKKFYPAMLTAFSTASSNATLPVTISCAINAGISRDVATVILPVAATINMQGAC
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHH
ATITLFTLFAFQALGIPIGFGEVITLVVLGFLGATAAAGVPGGAAIIAIATATTLGIPVE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHHCCCCC
AAGWMVGVHPAVDPFETMLNVIGDPIGALIVSKYVTKDFDEGKWKQ
CCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA