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The map label for this gene is udp [H]

Identifier: 218884149

GI number: 218884149

Start: 807600

End: 808454

Strand: Reverse

Name: udp [H]

Synonym: DKAM_0838

Alternate gene names: 218884149

Gene position: 808454-807600 (Counterclockwise)

Preceding gene: 218884150

Following gene: 218884148

Centisome position: 59.22

GC content: 49.01

Gene sequence:

>855_bases
ATGAGTGAGAGGCTCAAGAGCGCGAGTCGCCCCGAAAGCGAGGAGGGTAGACAATACCATTTACAAGTGAAGCCGGGGGA
TGTAAGCCGTTACATTCTCTTACCTGGGGACCCCGATAGAGTGCCATGGATAGCTAGCTTCTGGGATAAGGCATGGAGTG
TTGCAAAGCATAGAGAATACGTGACGTATAGCGGCTATTATAAGGGAGTATTTATCTCAGCTGCAAGTACCGGCATAGGG
GCACCGGCTACAGCGATAGCTATAGAGGAGCTTGCAAGAGTGGGTGGGGATACATTTATACGGGTCGGGACAACCGGGGC
TCTCACAAGGGGTATAAGTGTGGGAGATATAATAATATCCACTGGAGCGGTCAGGTTAGAGGGGACCAGTAAACACTATG
TTATGCCTGAATACCCCGCTGTAGCAAGCTACGATGTAGTCTTAGCACTGATAGAGGCTGCCGAAATTCTTGGAGTAAGA
TATCACGTGGGGTTAACGGCTAGCAGCGATAGCTTCTACGTAGGGCAGGAGAGACCAGGCTTCAAAGACTATCTACCCCC
GTTTCAAAGAGGCCTCGTACAGTATCTCAGGAGCGTTAACGTGTTAAACTTCGAGATGGAGGCAGCCTTAATCTTCACGC
TTGCAAATATATATGGGCTCAGAGCCGGAGCCGTGTGTGCAGCCATAGCTAATAGGGAGACCGAGGAATTCGTGGTGAAC
GCTGGGGTAGAGGACGCTATAAAAGTAGCTAATGAAGCAGTGAAAATACTGAGTGAATGGGATGAAGAGGTTAAGCGGAG
GGGTAAGAAGTATATAAGTGCGTCAATTATTAAGCAAGCCGCATCTAAACACTAG

Upstream 100 bases:

>100_bases
TACATAACTGGGAGACATACCTACGGGATCATAGATACCATTACTTTAAATACTGAAATATTCGAAGAAGATATAAAGTA
AAATACAAGGGGGCAATGAA

Downstream 100 bases:

>100_bases
GAGAGTCGTGACTATATATGGGTACCCCGATACATGTAAGCATAGGTAATTTTAACATAGACATAGCCGTATACATTGAT
AAAGCGCCAGGAATAGATGA

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSERLKSASRPESEEGRQYHLQVKPGDVSRYILLPGDPDRVPWIASFWDKAWSVAKHREYVTYSGYYKGVFISAASTGIG
APATAIAIEELARVGGDTFIRVGTTGALTRGISVGDIIISTGAVRLEGTSKHYVMPEYPAVASYDVVLALIEAAEILGVR
YHVGLTASSDSFYVGQERPGFKDYLPPFQRGLVQYLRSVNVLNFEMEAALIFTLANIYGLRAGAVCAAIANRETEEFVVN
AGVEDAIKVANEAVKILSEWDEEVKRRGKKYISASIIKQAASKH

Sequences:

>Translated_284_residues
MSERLKSASRPESEEGRQYHLQVKPGDVSRYILLPGDPDRVPWIASFWDKAWSVAKHREYVTYSGYYKGVFISAASTGIG
APATAIAIEELARVGGDTFIRVGTTGALTRGISVGDIIISTGAVRLEGTSKHYVMPEYPAVASYDVVLALIEAAEILGVR
YHVGLTASSDSFYVGQERPGFKDYLPPFQRGLVQYLRSVNVLNFEMEAALIFTLANIYGLRAGAVCAAIANRETEEFVVN
AGVEDAIKVANEAVKILSEWDEEVKRRGKKYISASIIKQAASKH
>Mature_283_residues
SERLKSASRPESEEGRQYHLQVKPGDVSRYILLPGDPDRVPWIASFWDKAWSVAKHREYVTYSGYYKGVFISAASTGIGA
PATAIAIEELARVGGDTFIRVGTTGALTRGISVGDIIISTGAVRLEGTSKHYVMPEYPAVASYDVVLALIEAAEILGVRY
HVGLTASSDSFYVGQERPGFKDYLPPFQRGLVQYLRSVNVLNFEMEAALIFTLANIYGLRAGAVCAAIANRETEEFVVNA
GVEDAIKVANEAVKILSEWDEEVKRRGKKYISASIIKQAASKH

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=244, Percent_Identity=43.0327868852459, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1790844, Length=242, Percent_Identity=30.1652892561983, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 31070; Mature: 30938

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLKSASRPESEEGRQYHLQVKPGDVSRYILLPGDPDRVPWIASFWDKAWSVAKHREY
CCCHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCE
VTYSGYYKGVFISAASTGIGAPATAIAIEELARVGGDTFIRVGTTGALTRGISVGDIIIS
EEECCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHEEEE
TGAVRLEGTSKHYVMPEYPAVASYDVVLALIEAAEILGVRYHVGLTASSDSFYVGQERPG
CCEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCEEECCCCCC
FKDYLPPFQRGLVQYLRSVNVLNFEMEAALIFTLANIYGLRAGAVCAAIANRETEEFVVN
CHHCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHEEE
AGVEDAIKVANEAVKILSEWDEEVKRRGKKYISASIIKQAASKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SERLKSASRPESEEGRQYHLQVKPGDVSRYILLPGDPDRVPWIASFWDKAWSVAKHREY
CCHHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCE
VTYSGYYKGVFISAASTGIGAPATAIAIEELARVGGDTFIRVGTTGALTRGISVGDIIIS
EEECCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHEEEE
TGAVRLEGTSKHYVMPEYPAVASYDVVLALIEAAEILGVRYHVGLTASSDSFYVGQERPG
CCEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCEEECCCCCC
FKDYLPPFQRGLVQYLRSVNVLNFEMEAALIFTLANIYGLRAGAVCAAIANRETEEFVVN
CHHCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHEEE
AGVEDAIKVANEAVKILSEWDEEVKRRGKKYISASIIKQAASKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]