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The map label for this gene is 218884126

Identifier: 218884126

GI number: 218884126

Start: 783224

End: 784489

Strand: Reverse

Name: 218884126

Synonym: DKAM_0815

Alternate gene names: NA

Gene position: 784489-783224 (Counterclockwise)

Preceding gene: 218884128

Following gene: 218884125

Centisome position: 57.46

GC content: 46.68

Gene sequence:

>1266_bases
ATGGTTTTACTTGATCTCTTAATTAGGAAGGCAGGTGTTATTGTGATGAATAAGGTTTATCTTGTAGAGAGCGTTATAGG
GGTAATCGCTTTAAGCGATGACGGCTCAATAATAGCGTATGCTAAGTCACCTGAGAGCATCGATGATAACGTGGAATACC
TGCTCAGCATTGAGAGAGGAGAGGAGACGCTACAGCATTCTGAGGTAATGGAGAAGCTGAAGGAGAGCGGTGTAACCAGT
GTAATTGTTGAAGCATTGCCGCTAGCTAGAATAGCGTCTACTCATGGACTAAGCCCTGAGATAGTGCCAGGTCACAATAT
CTTCATAGATGTAAGGGGGGATATCGCTGAATTAGCGGTTAAACTAGGATACGTTGACTCGCAGGAGAAATTCTTCGAGA
AGCTCCATAACATAATGCTTGAGTATACGAGGAGGAAATTAAGGAAGGAGGCTCAGAAAAGGGACTTACTGGCTGTGCAA
GCGATAAGGGCGACCGATGACATAGATAAAACAATAAACCTATATGTTGCGAGGCTCAGGGAATGGTATAGCATCCACTT
CCCAGAACTAGATGAACTAGTAAAGGAACACCCTGAGTACGCTAAGCTGGTATATGAGCTGGGACACCGCTCTAACTATA
CTGTGGAAAACCTCAGTAAACTAGGGTACAGCGAGGAAAAGGCTCGAAAGCTTGCTGAGGCGGCAAAGAACAGTATAGGT
GCTGACCTAAGTGATTTCGACATGAACTATATAAAGATACTGGCTGGAATAATACTGGATCTCTACAAGTTGAGAAGTAC
TCTGGACGAGTATATTGATGCAGTAATGAAGGAGGTTGCCCCGAATATCTCTGCGCTTGTAGGGCCTAAACTAGGGGCGA
GGCTACTGAGTCTAGCCGGGGGGCTAGAAAAACTAGCAGTCCTGCCAGCAAGCACCATACAGGTACTGGGTGCTGAGAAA
GCATTGTTCAGAGCCCTGAGAACCGGTGGCAAGCCGCCTAAGCATGGAGTGATCTTCCAGCATCCATTCATACATAAGAG
CCCTAAGTGGCAGAGAGGTAAGATAGCCAGGGCGCTGGCTGCAAAATTATCGATAGCAGCCAAGATCGACTACTTCAGTG
GCAGGTTAGCTGGAGACAAGCTGGTAAAGGAGCTCGAGGAGAGAGTTGAAGAAATAAAGAAACTATATCCTAAGCCTCCA
CCAAAAAAAGAGGAGGAGAAGAGGCCTAGGCCGCCTCCTAAATCCAGGAGGAAGGGTGGGAGGTGA

Upstream 100 bases:

>100_bases
TTAGGGGTTTGACTCCTTACTTTCCCAGCCTTTGTTAGCGAGCCATGGCTTGGCATATTGAACCACCTAACATGATAGTA
TAGTTTAGGGATATTTAAAT

Downstream 100 bases:

>100_bases
TCCATGTGAGTCAACCGGTCTCGGTAAAACCACATGAAAAATACTACGGGGTATACGTTGTAGAGCTTGATGACGGTAGC
CTTAAACTTGCCACAAGGAA

Product: C/D box methylation guide ribonucleoprotein complex aNOP56 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVLLDLLIRKAGVIVMNKVYLVESVIGVIALSDDGSIIAYAKSPESIDDNVEYLLSIERGEETLQHSEVMEKLKESGVTS
VIVEALPLARIASTHGLSPEIVPGHNIFIDVRGDIAELAVKLGYVDSQEKFFEKLHNIMLEYTRRKLRKEAQKRDLLAVQ
AIRATDDIDKTINLYVARLREWYSIHFPELDELVKEHPEYAKLVYELGHRSNYTVENLSKLGYSEEKARKLAEAAKNSIG
ADLSDFDMNYIKILAGIILDLYKLRSTLDEYIDAVMKEVAPNISALVGPKLGARLLSLAGGLEKLAVLPASTIQVLGAEK
ALFRALRTGGKPPKHGVIFQHPFIHKSPKWQRGKIARALAAKLSIAAKIDYFSGRLAGDKLVKELEERVEEIKKLYPKPP
PKKEEEKRPRPPPKSRRKGGR

Sequences:

>Translated_421_residues
MVLLDLLIRKAGVIVMNKVYLVESVIGVIALSDDGSIIAYAKSPESIDDNVEYLLSIERGEETLQHSEVMEKLKESGVTS
VIVEALPLARIASTHGLSPEIVPGHNIFIDVRGDIAELAVKLGYVDSQEKFFEKLHNIMLEYTRRKLRKEAQKRDLLAVQ
AIRATDDIDKTINLYVARLREWYSIHFPELDELVKEHPEYAKLVYELGHRSNYTVENLSKLGYSEEKARKLAEAAKNSIG
ADLSDFDMNYIKILAGIILDLYKLRSTLDEYIDAVMKEVAPNISALVGPKLGARLLSLAGGLEKLAVLPASTIQVLGAEK
ALFRALRTGGKPPKHGVIFQHPFIHKSPKWQRGKIARALAAKLSIAAKIDYFSGRLAGDKLVKELEERVEEIKKLYPKPP
PKKEEEKRPRPPPKSRRKGGR
>Mature_421_residues
MVLLDLLIRKAGVIVMNKVYLVESVIGVIALSDDGSIIAYAKSPESIDDNVEYLLSIERGEETLQHSEVMEKLKESGVTS
VIVEALPLARIASTHGLSPEIVPGHNIFIDVRGDIAELAVKLGYVDSQEKFFEKLHNIMLEYTRRKLRKEAQKRDLLAVQ
AIRATDDIDKTINLYVARLREWYSIHFPELDELVKEHPEYAKLVYELGHRSNYTVENLSKLGYSEEKARKLAEAAKNSIG
ADLSDFDMNYIKILAGIILDLYKLRSTLDEYIDAVMKEVAPNISALVGPKLGARLLSLAGGLEKLAVLPASTIQVLGAEK
ALFRALRTGGKPPKHGVIFQHPFIHKSPKWQRGKIARALAAKLSIAAKIDYFSGRLAGDKLVKELEERVEEIKKLYPKPP
PKKEEEKRPRPPPKSRRKGGR

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=311, Percent_Identity=36.9774919614148, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI7706254, Length=230, Percent_Identity=40.4347826086956, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI221136939, Length=312, Percent_Identity=27.8846153846154, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17562296, Length=258, Percent_Identity=42.2480620155039, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17509449, Length=260, Percent_Identity=41.9230769230769, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17510923, Length=258, Percent_Identity=30.6201550387597, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324886, Length=363, Percent_Identity=34.1597796143251, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6323226, Length=278, Percent_Identity=39.2086330935252, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6321528, Length=272, Percent_Identity=27.5735294117647, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28572126, Length=324, Percent_Identity=36.7283950617284, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17137636, Length=230, Percent_Identity=40.4347826086956, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21357435, Length=259, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 47155; Mature: 47155

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLDLLIRKAGVIVMNKVYLVESVIGVIALSDDGSIIAYAKSPESIDDNVEYLLSIERG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHHHHHH
EETLQHSEVMEKLKESGVTSVIVEALPLARIASTHGLSPEIVPGHNIFIDVRGDIAELAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEECCCHHHHHH
KLGYVDSQEKFFEKLHNIMLEYTRRKLRKEAQKRDLLAVQAIRATDDIDKTINLYVARLR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWYSIHFPELDELVKEHPEYAKLVYELGHRSNYTVENLSKLGYSEEKARKLAEAAKNSIG
HHHHCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCC
ADLSDFDMNYIKILAGIILDLYKLRSTLDEYIDAVMKEVAPNISALVGPKLGARLLSLAG
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHC
GLEKLAVLPASTIQVLGAEKALFRALRTGGKPPKHGVIFQHPFIHKSPKWQRGKIARALA
CHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
AKLSIAAKIDYFSGRLAGDKLVKELEERVEEIKKLYPKPPPKKEEEKRPRPPPKSRRKGG
HHHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHCCCCC
R
C
>Mature Secondary Structure
MVLLDLLIRKAGVIVMNKVYLVESVIGVIALSDDGSIIAYAKSPESIDDNVEYLLSIERG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHHHHHH
EETLQHSEVMEKLKESGVTSVIVEALPLARIASTHGLSPEIVPGHNIFIDVRGDIAELAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEEEECCCHHHHHH
KLGYVDSQEKFFEKLHNIMLEYTRRKLRKEAQKRDLLAVQAIRATDDIDKTINLYVARLR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWYSIHFPELDELVKEHPEYAKLVYELGHRSNYTVENLSKLGYSEEKARKLAEAAKNSIG
HHHHCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCC
ADLSDFDMNYIKILAGIILDLYKLRSTLDEYIDAVMKEVAPNISALVGPKLGARLLSLAG
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHC
GLEKLAVLPASTIQVLGAEKALFRALRTGGKPPKHGVIFQHPFIHKSPKWQRGKIARALA
CHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
AKLSIAAKIDYFSGRLAGDKLVKELEERVEEIKKLYPKPPPKKEEEKRPRPPPKSRRKGG
HHHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]