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The map label for this gene is tldD [C]

Identifier: 218884066

GI number: 218884066

Start: 727524

End: 728933

Strand: Direct

Name: tldD [C]

Synonym: DKAM_0755

Alternate gene names: 218884066

Gene position: 727524-728933 (Clockwise)

Preceding gene: 218884064

Following gene: 218884067

Centisome position: 53.29

GC content: 49.36

Gene sequence:

>1410_bases
GTGTTCCTCTTGGAGCCAATGATAGACCTAGATTACATCGTGAAAACCGGGCTGGAGCTCGGCGTGGACTTTATCGATGT
CCGCTACCAAGACTACTACTATGAATCCCTGGTTGTGGACAATGGTGTTTTAAGAGAGGCAACGGTCACTTACTCCAGTG
GTATAGGTGCAAGAGTTTTAGTAAAAGGACTGATGGGTTATGCCTCAACCAATGATCTAAGTAGGAGAGGTATGAGAGAG
GCCGTGGAGTCAGCTATTAAATTGGCCAGGGTACTAGGGCACCATGGGATGGAACAGGGATTACTCGAGCGCCCAGTCTA
CAGGGATAGGATTGTGAGTCACTATGGATTAAACCCTGAGAACGTGGATCTCTCAGAGAAGGTGGAACTATTATTCGACA
TGTATAAGGCTGGGAGAGGGGTACAGGGTATTTCAAGCCTCATTATTCCATACGGGTATGAGAGGGATCACAGGATATAC
GTCTCCAGTAGGGGAGACTACATTGATTTCACGCGGAGAATGATTGGGGTAGGGGTAAGGGCAGTGGCCAGCGTGGAGGG
TAGATACGAGATGCTGTGGACAAGCGAGTCAGGTGTAGCTGGGTGGGAGTTCATTAAGTCGTTCAACTGGCTTAACTACG
TTGCTGAGAACAGTAAGCTAGCCGTGGATGCAGCGAGGGCAGAGCATGTGAAACCGGGTAGATATGACATTGTGCTGGAT
AACGAGATTGTGGGACTAATGCTTCACGAGGCATTTGGGCATGCAAGCGAGGCAGACATAGTTGAAGCCGGTGGAAGCGT
CCTCGGCGGTAGAATCGGGGAAACCGTGGCCAGCCCCCTTGTCTCAATAATTGATGATGGAAGAGTCGAGGGAGGGGTCT
ACGTTCCCTATGATGATGAAGGAACCCCTAAGCTTAAAACATATACGGTGAGAAATGGCATGTTGTCATCCTTTCTCCAT
AGTCTTGTAACAGCGCGGGGGCTCGGAGCATCTCCTACTGGCAATGCCCGCGTAATGTCTTTTAGAAACACGTTACTGGT
GAGGCAGACGAACACCTATATGGAGCCCAGGGATTGGGAACCAGAGGAGATGATTAGGGATATGGGGAGGGGACTATATA
TCAGGGGTAAGGGTGCGATGGGAGGTGAGGTAAACCCGTTAACAGGTGCCTTCACGTTTACAAGTGGTCCAAGCTACATA
GTTGAAAACGGTGAGCCTATTAAACTAGTTAAAGGAGTCATGTTAAGTGGTATAATACTTGAGACACTGAAGAACGTGGA
TGCCGTGGGAAAAGACCTGGTTGTTAAAACAAGCGTGTTTGGTGGATGCGGTAAGAGCGGACAGATGGTTAGGGTAGGGG
ATGGAGGACCACATGTCAGGGTTAGGGGATTCACTATTGGGGGTGGCTAA

Upstream 100 bases:

>100_bases
TTACAGGTCGATGAATCTCTAGTTGCAGCCTCCAGTTCCCGGGAACGAAATATATATTTGTTAACAGAGACAATTATTTT
TAATTAGCCTCCCAATAAAG

Downstream 100 bases:

>100_bases
GCTTGCTCGAGAAGCTCTTGGAGATAGGTATTAGGAAAGGGTTGAGTGAAGTAGAGGTTTACTCCATTGAATCCAATATA
TTATCATTCACTGTATCAAA

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MFLLEPMIDLDYIVKTGLELGVDFIDVRYQDYYYESLVVDNGVLREATVTYSSGIGARVLVKGLMGYASTNDLSRRGMRE
AVESAIKLARVLGHHGMEQGLLERPVYRDRIVSHYGLNPENVDLSEKVELLFDMYKAGRGVQGISSLIIPYGYERDHRIY
VSSRGDYIDFTRRMIGVGVRAVASVEGRYEMLWTSESGVAGWEFIKSFNWLNYVAENSKLAVDAARAEHVKPGRYDIVLD
NEIVGLMLHEAFGHASEADIVEAGGSVLGGRIGETVASPLVSIIDDGRVEGGVYVPYDDEGTPKLKTYTVRNGMLSSFLH
SLVTARGLGASPTGNARVMSFRNTLLVRQTNTYMEPRDWEPEEMIRDMGRGLYIRGKGAMGGEVNPLTGAFTFTSGPSYI
VENGEPIKLVKGVMLSGIILETLKNVDAVGKDLVVKTSVFGGCGKSGQMVRVGDGGPHVRVRGFTIGGG

Sequences:

>Translated_469_residues
MFLLEPMIDLDYIVKTGLELGVDFIDVRYQDYYYESLVVDNGVLREATVTYSSGIGARVLVKGLMGYASTNDLSRRGMRE
AVESAIKLARVLGHHGMEQGLLERPVYRDRIVSHYGLNPENVDLSEKVELLFDMYKAGRGVQGISSLIIPYGYERDHRIY
VSSRGDYIDFTRRMIGVGVRAVASVEGRYEMLWTSESGVAGWEFIKSFNWLNYVAENSKLAVDAARAEHVKPGRYDIVLD
NEIVGLMLHEAFGHASEADIVEAGGSVLGGRIGETVASPLVSIIDDGRVEGGVYVPYDDEGTPKLKTYTVRNGMLSSFLH
SLVTARGLGASPTGNARVMSFRNTLLVRQTNTYMEPRDWEPEEMIRDMGRGLYIRGKGAMGGEVNPLTGAFTFTSGPSYI
VENGEPIKLVKGVMLSGIILETLKNVDAVGKDLVVKTSVFGGCGKSGQMVRVGDGGPHVRVRGFTIGGG
>Mature_469_residues
MFLLEPMIDLDYIVKTGLELGVDFIDVRYQDYYYESLVVDNGVLREATVTYSSGIGARVLVKGLMGYASTNDLSRRGMRE
AVESAIKLARVLGHHGMEQGLLERPVYRDRIVSHYGLNPENVDLSEKVELLFDMYKAGRGVQGISSLIIPYGYERDHRIY
VSSRGDYIDFTRRMIGVGVRAVASVEGRYEMLWTSESGVAGWEFIKSFNWLNYVAENSKLAVDAARAEHVKPGRYDIVLD
NEIVGLMLHEAFGHASEADIVEAGGSVLGGRIGETVASPLVSIIDDGRVEGGVYVPYDDEGTPKLKTYTVRNGMLSSFLH
SLVTARGLGASPTGNARVMSFRNTLLVRQTNTYMEPRDWEPEEMIRDMGRGLYIRGKGAMGGEVNPLTGAFTFTSGPSYI
VENGEPIKLVKGVMLSGIILETLKNVDAVGKDLVVKTSVFGGCGKSGQMVRVGDGGPHVRVRGFTIGGG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=29.1925465838509, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51337; Mature: 51337

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLEPMIDLDYIVKTGLELGVDFIDVRYQDYYYESLVVDNGVLREATVTYSSGIGARVL
CCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHEEEEEEECCCCEEEEEEEECCCCCHHHH
VKGLMGYASTNDLSRRGMREAVESAIKLARVLGHHGMEQGLLERPVYRDRIVSHYGLNPE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCC
NVDLSEKVELLFDMYKAGRGVQGISSLIIPYGYERDHRIYVSSRGDYIDFTRRMIGVGVR
CCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
AVASVEGRYEMLWTSESGVAGWEFIKSFNWLNYVAENSKLAVDAARAEHVKPGRYDIVLD
HHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCEEEEEC
NEIVGLMLHEAFGHASEADIVEAGGSVLGGRIGETVASPLVSIIDDGRVEGGVYVPYDDE
CCHHHHHHHHHHCCCCCCHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GTPKLKTYTVRNGMLSSFLHSLVTARGLGASPTGNARVMSFRNTLLVRQTNTYMEPRDWE
CCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECEEEEEECCCCCCCCCCC
PEEMIRDMGRGLYIRGKGAMGGEVNPLTGAFTFTSGPSYIVENGEPIKLVKGVMLSGIIL
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
ETLKNVDAVGKDLVVKTSVFGGCGKSGQMVRVGDGGPHVRVRGFTIGGG
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCC
>Mature Secondary Structure
MFLLEPMIDLDYIVKTGLELGVDFIDVRYQDYYYESLVVDNGVLREATVTYSSGIGARVL
CCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHEEEEEEECCCCEEEEEEEECCCCCHHHH
VKGLMGYASTNDLSRRGMREAVESAIKLARVLGHHGMEQGLLERPVYRDRIVSHYGLNPE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCC
NVDLSEKVELLFDMYKAGRGVQGISSLIIPYGYERDHRIYVSSRGDYIDFTRRMIGVGVR
CCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
AVASVEGRYEMLWTSESGVAGWEFIKSFNWLNYVAENSKLAVDAARAEHVKPGRYDIVLD
HHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCEEEEEC
NEIVGLMLHEAFGHASEADIVEAGGSVLGGRIGETVASPLVSIIDDGRVEGGVYVPYDDE
CCHHHHHHHHHHCCCCCCHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GTPKLKTYTVRNGMLSSFLHSLVTARGLGASPTGNARVMSFRNTLLVRQTNTYMEPRDWE
CCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECEEEEEECCCCCCCCCCC
PEEMIRDMGRGLYIRGKGAMGGEVNPLTGAFTFTSGPSYIVENGEPIKLVKGVMLSGIIL
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
ETLKNVDAVGKDLVVKTSVFGGCGKSGQMVRVGDGGPHVRVRGFTIGGG
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]