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The map label for this gene is cdd [H]

Identifier: 218883919

GI number: 218883919

Start: 572820

End: 573221

Strand: Direct

Name: cdd [H]

Synonym: DKAM_0608

Alternate gene names: 218883919

Gene position: 572820-573221 (Clockwise)

Preceding gene: 218883918

Following gene: 218883929

Centisome position: 41.96

GC content: 42.04

Gene sequence:

>402_bases
ATGAGTGTTAATATAAATATAGAGGGTTTAATCGATAAGGCAAAGCCATTTCTCAGTAATAGCTATGCACCCTATAGTAA
TATCCACGTTGCTGCAGCCGTCTTAACAGACAAAGGCAACATATATACCGGGGTAAACGTTGAGAACGCAAGCTATGGTT
TAACAATATGTGCTGAGCGTTCAGCCATCTCAGCAATGGTTGCAGCTGGTGAAAGGAGACCTGTTGCTGTAGCTGTTGTA
ACAGACATGGATAACCCAATACCGCCATGCGGAGCATGCAGGCAGGTTATAGCAGAGTTTAATCCAAAGGCATTAATCAT
AATGCATAGCGTTAAATCAGGGAAGACAATTGTGAAAAACCTTGAAGAACTCTTCCCGCAACCATTCATCCTTGAAAAGT
AG

Upstream 100 bases:

>100_bases
TGAAGATCATGCCAGGCTATAATGGAAGAGACTCATTGAGGGGCTTCACTCAGTCATGGGATATAAATGATGAAGAATAT
ATTATAGGGATTGAGGTAGT

Downstream 100 bases:

>100_bases
CTTGTTTTTCAGCCACCACGAGGATATTCCTTGTTAAACTAGGCTTACCCGGGTTCTCTATGAAATACCTGCGCTCCAAT
ATCGTAAAGCCTGCTTCACC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MSVNINIEGLIDKAKPFLSNSYAPYSNIHVAAAVLTDKGNIYTGVNVENASYGLTICAERSAISAMVAAGERRPVAVAVV
TDMDNPIPPCGACRQVIAEFNPKALIIMHSVKSGKTIVKNLEELFPQPFILEK

Sequences:

>Translated_133_residues
MSVNINIEGLIDKAKPFLSNSYAPYSNIHVAAAVLTDKGNIYTGVNVENASYGLTICAERSAISAMVAAGERRPVAVAVV
TDMDNPIPPCGACRQVIAEFNPKALIIMHSVKSGKTIVKNLEELFPQPFILEK
>Mature_132_residues
SVNINIEGLIDKAKPFLSNSYAPYSNIHVAAAVLTDKGNIYTGVNVENASYGLTICAERSAISAMVAAGERRPVAVAVVT
DMDNPIPPCGACRQVIAEFNPKALIIMHSVKSGKTIVKNLEELFPQPFILEK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=111, Percent_Identity=45.945945945946, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=122, Percent_Identity=44.2622950819672, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540514, Length=123, Percent_Identity=41.4634146341463, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=127, Percent_Identity=39.3700787401575, Blast_Score=87, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582741, Length=134, Percent_Identity=36.5671641791045, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582744, Length=81, Percent_Identity=44.4444444444444, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920920, Length=101, Percent_Identity=39.6039603960396, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14274; Mature: 14143

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNINIEGLIDKAKPFLSNSYAPYSNIHVAAAVLTDKGNIYTGVNVENASYGLTICAER
CEEEEEEHEEECCCCHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCEEEEECC
SAISAMVAAGERRPVAVAVVTDMDNPIPPCGACRQVIAEFNPKALIIMHSVKSGKTIVKN
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
LEELFPQPFILEK
HHHHCCCCEECCC
>Mature Secondary Structure 
SVNINIEGLIDKAKPFLSNSYAPYSNIHVAAAVLTDKGNIYTGVNVENASYGLTICAER
EEEEEEHEEECCCCHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCEEEEECC
SAISAMVAAGERRPVAVAVVTDMDNPIPPCGACRQVIAEFNPKALIIMHSVKSGKTIVKN
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
LEELFPQPFILEK
HHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]