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The map label for this gene is ahpC [C]

Identifier: 218883914

GI number: 218883914

Start: 565976

End: 566635

Strand: Reverse

Name: ahpC [C]

Synonym: DKAM_0603

Alternate gene names: 218883914

Gene position: 566635-565976 (Counterclockwise)

Preceding gene: 218883920

Following gene: 218883913

Centisome position: 41.5

GC content: 47.88

Gene sequence:

>660_bases
ATGGAAGTAGTGACCACGCATGGCAAGAAGAAGCTCCCCGATGACTATAAGGGTAAGTACCTCGTATTATTCAGCCACCC
AGCCGACTTCACACCGGTCTGTACCACTGAGTTCGTGGCATTCGCAAAGAGATACGAGGATTTTAAGAAACTGAATGCTG
AGCTACTTGGGCTAAGCGTTGACAGCGTCTTCTCCCATATCAAGTGGATTGAGTGGATCCAGGAGAAACTAGGCGTTGAA
ATACCCTTCCCAATAATAGCTGACCCTAATGGTGAAGTATCGAGGAGGCTCGGGTTCCTTCACGCTCAAAGTGCTACACA
TACCGTTAGGGCAGTAATCATCATTGATGGAAACGGCATCATAAGGGCTGTAATTTACTATCCACAGGAGACTGGGCGCA
ACATAGATGAAATACTGAGACTGGTAAAAGCGTTGCAGTTGAACGATAAGTATAAGAGAGCTGTGCCAGCTGGATGGCCT
AACAATGAATTAATCGGGGATGGATTAATCGTTCCACCAGCCTCAACGATACAGGAAGCAAAGGAGAGGGTTAAGCAGTA
TAAGTGCTTCGACTGGTGGCTATGCTACGAGGAAGGAAAGGTACCGCCCGAAGAAGTAAAGGAAGCGCGCTCCTGGCTTG
AAAGAGCCGCGAAACCCTAA

Upstream 100 bases:

>100_bases
TTATATATGGAAAAATTTATAAACCATTATAGTATATTTTATGAATTCGGTGGTGTAAATGCCTGGGCAAATCCCATTAA
TAGGCGAACCATTCCCTCAG

Downstream 100 bases:

>100_bases
ACCTAAAAGTAATTATTTTTTATTCTGAAATCATTCTAAAATCTTCCTGAGAGACATTGATAACTAACCCTGCTTATGGA
TGATAACATGATGGAATATA

Product: Peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MEVVTTHGKKKLPDDYKGKYLVLFSHPADFTPVCTTEFVAFAKRYEDFKKLNAELLGLSVDSVFSHIKWIEWIQEKLGVE
IPFPIIADPNGEVSRRLGFLHAQSATHTVRAVIIIDGNGIIRAVIYYPQETGRNIDEILRLVKALQLNDKYKRAVPAGWP
NNELIGDGLIVPPASTIQEAKERVKQYKCFDWWLCYEEGKVPPEEVKEARSWLERAAKP

Sequences:

>Translated_219_residues
MEVVTTHGKKKLPDDYKGKYLVLFSHPADFTPVCTTEFVAFAKRYEDFKKLNAELLGLSVDSVFSHIKWIEWIQEKLGVE
IPFPIIADPNGEVSRRLGFLHAQSATHTVRAVIIIDGNGIIRAVIYYPQETGRNIDEILRLVKALQLNDKYKRAVPAGWP
NNELIGDGLIVPPASTIQEAKERVKQYKCFDWWLCYEEGKVPPEEVKEARSWLERAAKP
>Mature_219_residues
MEVVTTHGKKKLPDDYKGKYLVLFSHPADFTPVCTTEFVAFAKRYEDFKKLNAELLGLSVDSVFSHIKWIEWIQEKLGVE
IPFPIIADPNGEVSRRLGFLHAQSATHTVRAVIIIDGNGIIRAVIYYPQETGRNIDEILRLVKALQLNDKYKRAVPAGWP
NNELIGDGLIVPPASTIQEAKERVKQYKCFDWWLCYEEGKVPPEEVKEARSWLERAAKP

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=174, Percent_Identity=39.0804597701149, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI32455266, Length=174, Percent_Identity=39.0804597701149, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI32455264, Length=174, Percent_Identity=39.0804597701149, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI5453549, Length=153, Percent_Identity=42.483660130719, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI32189392, Length=153, Percent_Identity=43.7908496732026, Blast_Score=130, Evalue=7e-31,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=38.7434554973822, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI5802974, Length=175, Percent_Identity=37.1428571428571, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483377, Length=175, Percent_Identity=37.1428571428571, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=62.0689655172414, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786822, Length=150, Percent_Identity=32, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32565831, Length=175, Percent_Identity=40, Blast_Score=126, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI193204376, Length=175, Percent_Identity=40, Blast_Score=126, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=146, Percent_Identity=38.3561643835616, Blast_Score=116, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=35.4166666666667, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=208, Percent_Identity=40.3846153846154, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=36.5714285714286, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320661, Length=173, Percent_Identity=34.6820809248555, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17975518, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24652434, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24652436, Length=191, Percent_Identity=38.7434554973822, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17738015, Length=152, Percent_Identity=41.4473684210526, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24656348, Length=145, Percent_Identity=39.3103448275862, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17864676, Length=145, Percent_Identity=39.3103448275862, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17157991, Length=146, Percent_Identity=41.0958904109589, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24641739, Length=146, Percent_Identity=41.0958904109589, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24581278, Length=175, Percent_Identity=38.8571428571429, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=36.986301369863, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24993; Mature: 24993

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVTTHGKKKLPDDYKGKYLVLFSHPADFTPVCTTEFVAFAKRYEDFKKLNAELLGLSV
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DSVFSHIKWIEWIQEKLGVEIPFPIIADPNGEVSRRLGFLHAQSATHTVRAVIIIDGNGI
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCE
IRAVIYYPQETGRNIDEILRLVKALQLNDKYKRAVPAGWPNNELIGDGLIVPPASTIQEA
EEEEEECCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHH
KERVKQYKCFDWWLCYEEGKVPPEEVKEARSWLERAAKP
HHHHHHCCHHHEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEVVTTHGKKKLPDDYKGKYLVLFSHPADFTPVCTTEFVAFAKRYEDFKKLNAELLGLSV
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DSVFSHIKWIEWIQEKLGVEIPFPIIADPNGEVSRRLGFLHAQSATHTVRAVIIIDGNGI
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCE
IRAVIYYPQETGRNIDEILRLVKALQLNDKYKRAVPAGWPNNELIGDGLIVPPASTIQEA
EEEEEECCHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHH
KERVKQYKCFDWWLCYEEGKVPPEEVKEARSWLERAAKP
HHHHHHCCHHHEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA