| Definition | Desulfurococcus kamchatkensis 1221n chromosome, complete genome. |
|---|---|
| Accession | NC_011766 |
| Length | 1,365,223 |
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The map label for this gene is appF [H]
Identifier: 218883702
GI number: 218883702
Start: 361916
End: 363034
Strand: Reverse
Name: appF [H]
Synonym: DKAM_0391
Alternate gene names: 218883702
Gene position: 363034-361916 (Counterclockwise)
Preceding gene: 218883703
Following gene: 218883701
Centisome position: 26.59
GC content: 45.4
Gene sequence:
>1119_bases ATGAGCGAGGAAAGAATATATGAGCCTAAGATAACATCTAACACCATATTGTTCGCGAAAAACCTGAGGGTATACTTCCC GGTAAGAAAGAGCTTTCTCGACATACTACGTGGAAGACCCCAGTTATACGTAAAAGCAGTCGATGGAGTATCCTTTGATA TAAGCAAGGGAGAGGTATTCGCATTAGTTGGCGAGTCGGGCTGTGGTAAAACAACCACGGGCAAAACCATATTGAGGCTT AATAAGCCCACGGAAGGCGAGATAGGTTATCTGCCCTCGAAGGAGATCCTCGAGGAAATGAGATCCTATGGAAGCATCAA TAACATCAGCGAATACGGCCATATAAGCCTAGCCTCACTCAATGAACACATGTTACGTCCCCTCAGAAAAGATGTCCAGA TGATATGGCAGGACCCCTTTGGAAGTCTTAATCCACGTAGAACCATATATGAGATCCTTGAAGAGCCCCTTGCAATCCAT GGAGTGGGTGTGAGTCGTGAGGACAGATACGATATAGTGGCAAAAGCGCTTGAATCGGTTAAACTGACGCCACCAGATGA ATACATGGATAGATATCCGCATATGTTGTCTGGTGGGCAAAGACAGCGTGTAGTAATAGCGAGGGCGCTAATACTTAATC CCAAGTTCGTAGTGGCCGATGAACCTGTCTCAATGCTTGATGTCTCAATAAGGGCTGAGATACTCCAGTTAATGATGGAG CTTAAGAATAAACTAGGGCTAACATACCTATTCATTACCCATGACCTAGCTGTTGCAAGATATATATCCAATAGGCTCGC AGTAATGTATCTTGGACAAATAGTTGAAATAGGTGATGCTAGAAGGGTCATCGAGAATCCATTACATCCCTACACTAGGG CTCTTGTAGAGGCCATACCGGAGCCCGAACCATCGAGAAGGCTTGCCATTAGGGAGATACCTATTAAGGGTGAAGTCCCC TCACCTATAAATATCCCAGCCGGATGCAGGTTCCATCCAAGATGTGTTGCACTTGATGAGAAACCAGAGTTGAGAGAATA TTGTATGAAGAGAGAACCCCCGTTGGTCGAGGTTGAGCCAGGCCACTACGTCAAGTGCTGGCTATACGCTAAAAAATGA
Upstream 100 bases:
>100_bases GCCCCAAGGCATTTAATAAATGCAGTGAGAAACCCCCGTTGGTCGAGGTTGAGCCAGGCCACTACGTCAAGTGCTGGCTA TACGCTAAGGGGTGATTGGG
Downstream 100 bases:
>100_bases TTTTTATCGAGGTAATAAAATAGTGTAGAGGGATGCCTTTATGATTCCTGAGGAACGGGTAGGGATAATTGGCTGGGGCT CATATATACCTAGGTGGAGA
Product: oligopeptide/dipeptide ABC transporter ATPase
Products: ADP; phosphate; dipeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 372; Mature: 371
Protein sequence:
>372_residues MSEERIYEPKITSNTILFAKNLRVYFPVRKSFLDILRGRPQLYVKAVDGVSFDISKGEVFALVGESGCGKTTTGKTILRL NKPTEGEIGYLPSKEILEEMRSYGSINNISEYGHISLASLNEHMLRPLRKDVQMIWQDPFGSLNPRRTIYEILEEPLAIH GVGVSREDRYDIVAKALESVKLTPPDEYMDRYPHMLSGGQRQRVVIARALILNPKFVVADEPVSMLDVSIRAEILQLMME LKNKLGLTYLFITHDLAVARYISNRLAVMYLGQIVEIGDARRVIENPLHPYTRALVEAIPEPEPSRRLAIREIPIKGEVP SPINIPAGCRFHPRCVALDEKPELREYCMKREPPLVEVEPGHYVKCWLYAKK
Sequences:
>Translated_372_residues MSEERIYEPKITSNTILFAKNLRVYFPVRKSFLDILRGRPQLYVKAVDGVSFDISKGEVFALVGESGCGKTTTGKTILRL NKPTEGEIGYLPSKEILEEMRSYGSINNISEYGHISLASLNEHMLRPLRKDVQMIWQDPFGSLNPRRTIYEILEEPLAIH GVGVSREDRYDIVAKALESVKLTPPDEYMDRYPHMLSGGQRQRVVIARALILNPKFVVADEPVSMLDVSIRAEILQLMME LKNKLGLTYLFITHDLAVARYISNRLAVMYLGQIVEIGDARRVIENPLHPYTRALVEAIPEPEPSRRLAIREIPIKGEVP SPINIPAGCRFHPRCVALDEKPELREYCMKREPPLVEVEPGHYVKCWLYAKK >Mature_371_residues SEERIYEPKITSNTILFAKNLRVYFPVRKSFLDILRGRPQLYVKAVDGVSFDISKGEVFALVGESGCGKTTTGKTILRLN KPTEGEIGYLPSKEILEEMRSYGSINNISEYGHISLASLNEHMLRPLRKDVQMIWQDPFGSLNPRRTIYEILEEPLAIHG VGVSREDRYDIVAKALESVKLTPPDEYMDRYPHMLSGGQRQRVVIARALILNPKFVVADEPVSMLDVSIRAEILQLMMEL KNKLGLTYLFITHDLAVARYISNRLAVMYLGQIVEIGDARRVIENPLHPYTRALVEAIPEPEPSRRLAIREIPIKGEVPS PINIPAGCRFHPRCVALDEKPELREYCMKREPPLVEVEPGHYVKCWLYAKK
Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin
COG id: COG4608
COG function: function code E; ABC-type oligopeptide transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI171184400, Length=253, Percent_Identity=29.6442687747036, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI153792144, Length=305, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI42490749, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI9665248, Length=256, Percent_Identity=27.34375, Blast_Score=71, Evalue=1e-12, Organism=Escherichia coli, GI1789962, Length=338, Percent_Identity=42.0118343195266, Blast_Score=267, Evalue=1e-72, Organism=Escherichia coli, GI1787500, Length=355, Percent_Identity=41.4084507042254, Blast_Score=254, Evalue=9e-69, Organism=Escherichia coli, GI145693107, Length=310, Percent_Identity=46.1290322580645, Blast_Score=251, Evalue=7e-68, Organism=Escherichia coli, GI1787758, Length=357, Percent_Identity=36.1344537815126, Blast_Score=230, Evalue=1e-61, Organism=Escherichia coli, GI48994883, Length=356, Percent_Identity=33.9887640449438, Blast_Score=199, Evalue=2e-52, Organism=Escherichia coli, GI1789963, Length=324, Percent_Identity=36.7283950617284, Blast_Score=194, Evalue=9e-51, Organism=Escherichia coli, GI1788506, Length=284, Percent_Identity=39.0845070422535, Blast_Score=186, Evalue=3e-48, Organism=Escherichia coli, GI1787759, Length=302, Percent_Identity=36.0927152317881, Blast_Score=165, Evalue=3e-42, Organism=Escherichia coli, GI1787547, Length=282, Percent_Identity=33.6879432624113, Blast_Score=160, Evalue=1e-40, Organism=Escherichia coli, GI1789891, Length=254, Percent_Identity=35.8267716535433, Blast_Score=155, Evalue=3e-39, Organism=Escherichia coli, GI1787548, Length=298, Percent_Identity=30.2013422818792, Blast_Score=137, Evalue=1e-33, Organism=Escherichia coli, GI48994997, Length=255, Percent_Identity=36.8627450980392, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI1787712, Length=253, Percent_Identity=33.9920948616601, Blast_Score=123, Evalue=2e-29, Organism=Escherichia coli, GI1789032, Length=255, Percent_Identity=30.5882352941176, Blast_Score=121, Evalue=8e-29, Organism=Escherichia coli, GI87081791, Length=254, Percent_Identity=30.7086614173228, Blast_Score=120, Evalue=2e-28, Organism=Escherichia coli, GI1788225, Length=250, Percent_Identity=32.8, Blast_Score=119, Evalue=4e-28, Organism=Escherichia coli, GI1786398, Length=268, Percent_Identity=29.8507462686567, Blast_Score=119, Evalue=5e-28, Organism=Escherichia coli, GI1787089, Length=252, Percent_Identity=32.1428571428571, Blast_Score=114, Evalue=1e-26, Organism=Escherichia coli, GI87081709, Length=241, Percent_Identity=29.8755186721992, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1789890, Length=254, Percent_Identity=31.496062992126, Blast_Score=109, Evalue=3e-25, Organism=Escherichia coli, GI1787370, Length=261, Percent_Identity=28.3524904214559, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082267, Length=316, Percent_Identity=26.5822784810127, Blast_Score=106, Evalue=3e-24, Organism=Escherichia coli, GI1787029, Length=245, Percent_Identity=30.2040816326531, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI87081834, Length=217, Percent_Identity=35.4838709677419, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1788644, Length=247, Percent_Identity=31.1740890688259, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788450, Length=254, Percent_Identity=31.496062992126, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1788761, Length=280, Percent_Identity=30, Blast_Score=99, Evalue=7e-22, Organism=Escherichia coli, GI1789873, Length=230, Percent_Identity=32.6086956521739, Blast_Score=98, Evalue=1e-21, Organism=Escherichia coli, GI1789672, Length=254, Percent_Identity=27.9527559055118, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786872, Length=224, Percent_Identity=31.6964285714286, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI1790467, Length=232, Percent_Identity=29.3103448275862, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI1790162, Length=253, Percent_Identity=28.8537549407115, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1786563, Length=227, Percent_Identity=28.1938325991189, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=31.390134529148, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786319, Length=236, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=3e-16, Organism=Escherichia coli, GI1787164, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI1786703, Length=244, Percent_Identity=30.7377049180328, Blast_Score=79, Evalue=6e-16, Organism=Escherichia coli, GI1787112, Length=264, Percent_Identity=29.9242424242424, Blast_Score=78, Evalue=9e-16, Organism=Escherichia coli, GI1786803, Length=290, Percent_Identity=26.2068965517241, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1790739, Length=263, Percent_Identity=29.6577946768061, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1790534, Length=239, Percent_Identity=28.0334728033473, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI1786253, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789593, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789586, Length=260, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=2e-11, Organism=Escherichia coli, GI1787143, Length=255, Percent_Identity=26.2745098039216, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17558664, Length=284, Percent_Identity=28.8732394366197, Blast_Score=90, Evalue=2e-18, Organism=Caenorhabditis elegans, GI25146777, Length=285, Percent_Identity=28.4210526315789, Blast_Score=88, Evalue=7e-18, Organism=Caenorhabditis elegans, GI71996809, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193211015, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193211017, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17541710, Length=243, Percent_Identity=30.0411522633745, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI212646699, Length=284, Percent_Identity=27.112676056338, Blast_Score=79, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17567269, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115535101, Length=270, Percent_Identity=26.2962962962963, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI115533608, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324985, Length=278, Percent_Identity=27.3381294964029, Blast_Score=79, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6322640, Length=238, Percent_Identity=28.9915966386555, Blast_Score=66, Evalue=7e-12, Organism=Drosophila melanogaster, GI24659289, Length=253, Percent_Identity=25.6916996047431, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI281363262, Length=270, Percent_Identity=27.037037037037, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24653245, Length=270, Percent_Identity=27.037037037037, Blast_Score=69, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 42396; Mature: 42265
Theoretical pI: Translated: 8.42; Mature: 8.42
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEERIYEPKITSNTILFAKNLRVYFPVRKSFLDILRGRPQLYVKAVDGVSFDISKGEVF CCCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHCCCCEEEEEEECCCEEEECCCEEE ALVGESGCGKTTTGKTILRLNKPTEGEIGYLPSKEILEEMRSYGSINNISEYGHISLASL EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEHH NEHMLRPLRKDVQMIWQDPFGSLNPRRTIYEILEEPLAIHGVGVSREDRYDIVAKALESV HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHC KLTPPDEYMDRYPHMLSGGQRQRVVIARALILNPKFVVADEPVSMLDVSIRAEILQLMME CCCCCHHHHHHCCHHHCCCCCHHHHEEHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH LKNKLGLTYLFITHDLAVARYISNRLAVMYLGQIVEIGDARRVIENPLHPYTRALVEAIP HHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCC EPEPSRRLAIREIPIKGEVPSPINIPAGCRFHPRCVALDEKPELREYCMKREPPLVEVEP CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECC GHYVKCWLYAKK CCEEEEEEEECC >Mature Secondary Structure SEERIYEPKITSNTILFAKNLRVYFPVRKSFLDILRGRPQLYVKAVDGVSFDISKGEVF CCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHCCCCEEEEEEECCCEEEECCCEEE ALVGESGCGKTTTGKTILRLNKPTEGEIGYLPSKEILEEMRSYGSINNISEYGHISLASL EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEHH NEHMLRPLRKDVQMIWQDPFGSLNPRRTIYEILEEPLAIHGVGVSREDRYDIVAKALESV HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHC KLTPPDEYMDRYPHMLSGGQRQRVVIARALILNPKFVVADEPVSMLDVSIRAEILQLMME CCCCCHHHHHHCCHHHCCCCCHHHHEEHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH LKNKLGLTYLFITHDLAVARYISNRLAVMYLGQIVEIGDARRVIENPLHPYTRALVEAIP HHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCC EPEPSRRLAIREIPIKGEVPSPINIPAGCRFHPRCVALDEKPELREYCMKREPPLVEVEP CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECC GHYVKCWLYAKK CCEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; dipeptides [Periplasm]; H2O [C]
Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7997159; 9384377 [H]