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The map label for this gene is fusA2 [H]

Identifier: 218710417

GI number: 218710417

Start: 2622150

End: 2624237

Strand: Reverse

Name: fusA2 [H]

Synonym: VS_2454

Alternate gene names: 218710417

Gene position: 2624237-2622150 (Counterclockwise)

Preceding gene: 218710418

Following gene: 218710414

Centisome position: 79.54

GC content: 44.83

Gene sequence:

>2088_bases
ATGGCAGATTTATCGAAATACAGAAACATTGGTATTTTCGCGCACGTTGATGCGGGTAAAACAACTACCACTGAGCGTAT
CCTTAAGCTAACTGGTCAGATCCACAAGACTGGTGAAGTACATGATGGCGAATCAACTACTGACTTCATGGAACAGGAAG
CTGAGCGCGGAATTACTATCCAATCAGCAGCTGTAAGCTGTTTCTGGAACGGTCACCGTCTAAACGTTATCGATACTCCT
GGACACGTTGACTTCACAGTTGAAGTATACCGTTCTCTTAAAGTACTTGATGGCGGTATCGGTGTATTCTGTGGTTCTGG
TGGTGTTGAACCACAATCAGAAACTAACTGGCGCTACGCTAACGAATCAGAAGTATCTCGTCTGATCTTCGTTAACAAAC
TAGACCGTATGGGTGCAGATTTCTACAACGTTGTTGACCAAGTTAAAAACGTTCTAGGTGCAACTCCTCTAGTTATGGTT
CTACCAATCGGCCGCGAAGATGAATTCGTGGGTGTTGTAGACCTTCTAAGCCGTAAAGCATACGTTTGGGATGACACTGG
TCTTCCTGAAAACTACGAAATCACTGATGTTCCTGCGGACATGGTTGATGACGTTGAGCAATACCGTGAAGAGCTAATCG
AAACTGCTGTAGAGCAAGACGATGACCTAATGGAAGCTTACATGGAAGGTGAAGAGCCTTCTATCGAAGATATCAAACGT
TGTATCCGTAAAGGTACTCGTGATATTGCATTCTTCCCTACGTTCTGTGGTTCTGCGTTCAAGAACAAAGGCATGCAAGT
TATCCTTGATGCTGTAGTAGATTACCTACCTTCTCCAACTGAAGTTGATCCTCAACCTCTAATGGATGAGAACGGCGAAG
AAACAGGCAAGCACGCTATCGTTTCTACTGAAGAAACTTTCAAAGCGCTTGCGTTCAAAATCATGGATGACCGTTTCGGT
GCTCTAACTTTCGTTCGTATTTACTCTGGTAAATTGAACAAAGGTGACACGATCCTTAACTCATTCACAGGTAAAACTGA
GCGTGTTGGCCGTATGGTTGAGATGCAAGCTGATGACCGTAACGAACTAACTAGCGCACAAGCTGGTGACATCATTGCGA
TCGTTGGTATGAAGAACGTTCAAACTGGTCACACTCTATGTGATCCAAAAGACCAAGTAACGCTTGAGCCAATGGTTTTC
CCAACTCCAGTAATCTCTATCGCTGTATCTCCAAAAGATAAAGGCGGTTCTGAGAAAATGGGTATCGCGATCGGTAAAAT
GGTTGCAGAAGATCCATCTTTCCAAGTTGAGACTGACGAAGAAACTGGCGAAACTATCCTTAAAGGTATGGGTGAGCTTC
ACCTAGACATCAAGGTAGATATCCTTAAGCGTACTTACGGCGTTGACCTAACAGTTGGTGCTCCTCAAGTTGCTTACCGT
GAAACTATCACTCAAGCAATTGAAGATAGCTACACGCATAAGAAACAGTCTGGTGGTTCTGGTCAATTCGGTAAGATCGA
TTACCGTATTAAACCAGGTGAAGCAGGTTCTGGCTTCAAGTTCAACTCAGTAGTTGTGGGCGGTAACGTTCCTAAAGAAT
TCTGGCCTGCAGTTGAGAAAGGCTTTGCTGGCATGATGGATAACGGCGTACTAGCTGGCTTCCCTACGCTAGACGTTGAA
GTTGAACTTTTCGATGGTGGTTTCCACGCAGTCGATTCATCTGCTATCGCATTTGAAATCGCAGCGAAAGGCGCATTCCG
TCAATCTATGCCTAAAGCTGGCGCGCAACTTCTTGAGCCTATCATGAACGTTGACGTGTTCACTCCAGACGATCACGTTG
GTGATGTTATCGGTGACCTTAACCGTCGTCGTGGCATGATCAAAGATCAACAAGCTGGCGTTACTGGTGTTCGTATTAAA
GCTGACGTACCTCTTTCTGAGATGTTCGGCTACATCGGTCACCTACGTACTATCACTTCTGGTCGTGGCCAATTCTCTAT
GGAATTCGCACAATACGCACCATGTCCAACTAACGTTGCTGACGAAGTGATTGCAAAAGTTAAAGCAGAAAAAGAAGCTG
GTAAGTAA

Upstream 100 bases:

>100_bases
AGGCAAAGTTTTTTAGTCCCAAATGCATGCAAAGCTATCAGTCCTCACAGATTGTGATATACTCTGCGCGCATTTTATAT
CCTATTAACAGAGTAAGACA

Downstream 100 bases:

>100_bases
TTAGCCCTTTTCTAAATTAGCTAAAAAAGCCCCGCAAGTGAAAGCTTGCGGGGCTTTTTATTGTTTGTAATATACTGCGA
GGTGCGAGGTGCGAGGTGCG

Product: elongation factor G

Products: NA

Alternate protein names: EF-G 2 [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITIQSAAVSCFWNGHRLNVIDTP
GHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMV
LPIGREDEFVGVVDLLSRKAYVWDDTGLPENYEITDVPADMVDDVEQYREELIETAVEQDDDLMEAYMEGEEPSIEDIKR
CIRKGTRDIAFFPTFCGSAFKNKGMQVILDAVVDYLPSPTEVDPQPLMDENGEETGKHAIVSTEETFKALAFKIMDDRFG
ALTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMQADDRNELTSAQAGDIIAIVGMKNVQTGHTLCDPKDQVTLEPMVF
PTPVISIAVSPKDKGGSEKMGIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLTVGAPQVAYR
ETITQAIEDSYTHKKQSGGSGQFGKIDYRIKPGEAGSGFKFNSVVVGGNVPKEFWPAVEKGFAGMMDNGVLAGFPTLDVE
VELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGAQLLEPIMNVDVFTPDDHVGDVIGDLNRRRGMIKDQQAGVTGVRIK
ADVPLSEMFGYIGHLRTITSGRGQFSMEFAQYAPCPTNVADEVIAKVKAEKEAGK

Sequences:

>Translated_695_residues
MADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITIQSAAVSCFWNGHRLNVIDTP
GHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMV
LPIGREDEFVGVVDLLSRKAYVWDDTGLPENYEITDVPADMVDDVEQYREELIETAVEQDDDLMEAYMEGEEPSIEDIKR
CIRKGTRDIAFFPTFCGSAFKNKGMQVILDAVVDYLPSPTEVDPQPLMDENGEETGKHAIVSTEETFKALAFKIMDDRFG
ALTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMQADDRNELTSAQAGDIIAIVGMKNVQTGHTLCDPKDQVTLEPMVF
PTPVISIAVSPKDKGGSEKMGIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLTVGAPQVAYR
ETITQAIEDSYTHKKQSGGSGQFGKIDYRIKPGEAGSGFKFNSVVVGGNVPKEFWPAVEKGFAGMMDNGVLAGFPTLDVE
VELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGAQLLEPIMNVDVFTPDDHVGDVIGDLNRRRGMIKDQQAGVTGVRIK
ADVPLSEMFGYIGHLRTITSGRGQFSMEFAQYAPCPTNVADEVIAKVKAEKEAGK
>Mature_694_residues
ADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITIQSAAVSCFWNGHRLNVIDTPG
HVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMVL
PIGREDEFVGVVDLLSRKAYVWDDTGLPENYEITDVPADMVDDVEQYREELIETAVEQDDDLMEAYMEGEEPSIEDIKRC
IRKGTRDIAFFPTFCGSAFKNKGMQVILDAVVDYLPSPTEVDPQPLMDENGEETGKHAIVSTEETFKALAFKIMDDRFGA
LTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMQADDRNELTSAQAGDIIAIVGMKNVQTGHTLCDPKDQVTLEPMVFP
TPVISIAVSPKDKGGSEKMGIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLTVGAPQVAYRE
TITQAIEDSYTHKKQSGGSGQFGKIDYRIKPGEAGSGFKFNSVVVGGNVPKEFWPAVEKGFAGMMDNGVLAGFPTLDVEV
ELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGAQLLEPIMNVDVFTPDDHVGDVIGDLNRRRGMIKDQQAGVTGVRIKA
DVPLSEMFGYIGHLRTITSGRGQFSMEFAQYAPCPTNVADEVIAKVKAEKEAGK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=693, Percent_Identity=42.7128427128427, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI19923640, Length=711, Percent_Identity=35.7243319268636, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI25306283, Length=396, Percent_Identity=41.6666666666667, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI25306287, Length=290, Percent_Identity=45.1724137931035, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI157426893, Length=159, Percent_Identity=38.9937106918239, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI4503483, Length=146, Percent_Identity=36.986301369863, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI94966754, Length=158, Percent_Identity=32.2784810126582, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI310132016, Length=122, Percent_Identity=36.0655737704918, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI310110807, Length=122, Percent_Identity=36.0655737704918, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI310123363, Length=122, Percent_Identity=36.0655737704918, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789738, Length=693, Percent_Identity=53.3910533910534, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=500, Percent_Identity=25.6, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI48994988, Length=175, Percent_Identity=36, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788922, Length=180, Percent_Identity=33.8888888888889, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=698, Percent_Identity=39.3982808022923, Blast_Score=491, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17556745, Length=721, Percent_Identity=30.5131761442441, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17557151, Length=151, Percent_Identity=39.7350993377483, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17552882, Length=162, Percent_Identity=31.4814814814815, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=700, Percent_Identity=40.7142857142857, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6322359, Length=771, Percent_Identity=32.0363164721141, Blast_Score=346, Evalue=9e-96,
Organism=Saccharomyces cerevisiae, GI6323320, Length=153, Percent_Identity=37.2549019607843, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324707, Length=154, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320593, Length=154, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324166, Length=179, Percent_Identity=29.608938547486, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582462, Length=694, Percent_Identity=40.2017291066282, Blast_Score=528, Evalue=1e-150,
Organism=Drosophila melanogaster, GI221458488, Length=735, Percent_Identity=32.9251700680272, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI78706572, Length=158, Percent_Identity=37.9746835443038, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28574573, Length=171, Percent_Identity=33.9181286549708, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24585709, Length=151, Percent_Identity=36.4238410596026, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24585711, Length=151, Percent_Identity=36.4238410596026, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24585713, Length=151, Percent_Identity=36.4238410596026, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 76068; Mature: 75937

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITI
CCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEE
QSAAVSCFWNGHRLNVIDTPGHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYA
EEEEEEEEECCEEEEEEECCCCEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
NESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMVLPIGREDEFVGVVDLLSRKA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCC
YVWDDTGLPENYEITDVPADMVDDVEQYREELIETAVEQDDDLMEAYMEGEEPSIEDIKR
EEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHH
CIRKGTRDIAFFPTFCGSAFKNKGMQVILDAVVDYLPSPTEVDPQPLMDENGEETGKHAI
HHHCCCCCEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VSTEETFKALAFKIMDDRFGALTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMQADDR
EECHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHHCCEEEECCCCC
NELTSAQAGDIIAIVGMKNVQTGHTLCDPKDQVTLEPMVFPTPVISIAVSPKDKGGSEKM
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCEECCCCEEEEEECCCCCCCCCCH
GIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLTVGAPQVAYR
HHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEEEEEEEEHHHCCCEEEECCCHHHHH
ETITQAIEDSYTHKKQSGGSGQFGKIDYRIKPGEAGSGFKFNSVVVGGNVPKEFWPAVEK
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEECEEEECCCCCHHHHHHHHH
GFAGMMDNGVLAGFPTLDVEVELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGAQLLEP
CCCCCCCCCEEECCCCEEEEEEEECCCCEECCCCCEEEEEHHCCHHHHHCCHHHHHHHHH
IMNVDVFTPDDHVGDVIGDLNRRRGMIKDQQAGVTGVRIKADVPLSEMFGYIGHLRTITS
HHCCEEECCCHHHHHHHHHHHHHCCCCCHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
GRGQFSMEFAQYAPCPTNVADEVIAKVKAEKEAGK
CCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADLSKYRNIGIFAHVDAGKTTTTERILKLTGQIHKTGEVHDGESTTDFMEQEAERGITI
CCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEE
QSAAVSCFWNGHRLNVIDTPGHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYA
EEEEEEEEECCEEEEEEECCCCEEEHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
NESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMVLPIGREDEFVGVVDLLSRKA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCC
YVWDDTGLPENYEITDVPADMVDDVEQYREELIETAVEQDDDLMEAYMEGEEPSIEDIKR
EEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHH
CIRKGTRDIAFFPTFCGSAFKNKGMQVILDAVVDYLPSPTEVDPQPLMDENGEETGKHAI
HHHCCCCCEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VSTEETFKALAFKIMDDRFGALTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMQADDR
EECHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHHCCEEEECCCCC
NELTSAQAGDIIAIVGMKNVQTGHTLCDPKDQVTLEPMVFPTPVISIAVSPKDKGGSEKM
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCEECCCCEEEEEECCCCCCCCCCH
GIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLTVGAPQVAYR
HHHHHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEEEEEEEEHHHCCCEEEECCCHHHHH
ETITQAIEDSYTHKKQSGGSGQFGKIDYRIKPGEAGSGFKFNSVVVGGNVPKEFWPAVEK
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEECEEEECCCCCHHHHHHHHH
GFAGMMDNGVLAGFPTLDVEVELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGAQLLEP
CCCCCCCCCEEECCCCEEEEEEEECCCCEECCCCCEEEEEHHCCHHHHHCCHHHHHHHHH
IMNVDVFTPDDHVGDVIGDLNRRRGMIKDQQAGVTGVRIKADVPLSEMFGYIGHLRTITS
HHCCEEECCCHHHHHHHHHHHHHCCCCCHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
GRGQFSMEFAQYAPCPTNVADEVIAKVKAEKEAGK
CCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA