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The map label for this gene is fabZ

Identifier: 218710307

GI number: 218710307

Start: 2510324

End: 2510776

Strand: Reverse

Name: fabZ

Synonym: VS_2341

Alternate gene names: 218710307

Gene position: 2510776-2510324 (Counterclockwise)

Preceding gene: 218710308

Following gene: 218710306

Centisome position: 76.1

GC content: 42.16

Gene sequence:

>453_bases
TTGACTACTGAACAGACAACGATGAACATTACTGAAATTCAGGAACTATTACCTCATCGCTACCCATTCTTAATGGTTGA
TCGTGTGACTAGCTTTGAAAAAGAAAAGACACTGACTGCGATTAAGAATGTTTCTGTTAACGAACCTCAGTTCACAGGCC
ACTTCCCACAACTTCCTGTATTCCCAGGTGTGTTGATCTTAGAAGCAATGGCGCAAGCAACAGGTCTTCTAGCATTTAAA
TCTTTTGGTGCTCCTTCTGGTAATGAGCTTTACTACTTTGCTAGCGTAGATAAAGCGAAGTTCCGCAAGCCAGTAGTGCC
TGGTGACCAATTGGTTATCGAAGTTGAGTTCTTAAAAGAACGTCGTGGCATTGCATCGTTCAACGGTGTAGCGAAAGTTG
ACGGCGTAGTTGTATGTTCAGCTGAACTTAAATGTGCTCGTAGAGAGTTTTAA

Upstream 100 bases:

>100_bases
ATCATAATTCCAGCATTTCTAATAAAAGGCTCGCGTACAGCGAGTCTTTTTCGTTTATAATCCTTCTCATTAAATAAAGA
ATATACATAGGAATACGACT

Downstream 100 bases:

>100_bases
TATGATTCATGAAACAGCGAAAATTCACCCGGCAGCAGTAATCGAAGGTGATGTAACTATCGGTGCTAACGTGACGGTTG
GTCCTTTCACTTACATTGCT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFK
SFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKERRGIASFNGVAKVDGVVVCSAELKCARREF

Sequences:

>Translated_150_residues
MTTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFK
SFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKERRGIASFNGVAKVDGVVVCSAELKCARREF
>Mature_149_residues
TTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFKS
FGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKERRGIASFNGVAKVDGVVVCSAELKCARREF

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=147, Percent_Identity=65.3061224489796, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_VIBSL (B7VIQ7)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417928.1
- ProteinModelPortal:   B7VIQ7
- SMR:   B7VIQ7
- GeneID:   7162751
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2341
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16730; Mature: 16598

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPV
CCCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGLLAFKSFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCCCCCCCEEEEEHHHHHH
RRGIASFNGVAKVDGVVVCSAELKCARREF
HCCCCCCCCCEECCEEEEECCHHHHHHCCC
>Mature Secondary Structure 
TTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPV
CCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
FPGVLILEAMAQATGLLAFKSFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCCCCCCCEEEEEHHHHHH
RRGIASFNGVAKVDGVVVCSAELKCARREF
HCCCCCCCCCEECCEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA