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The map label for this gene is mcrC [C]

Identifier: 218709373

GI number: 218709373

Start: 1496680

End: 1498011

Strand: Direct

Name: mcrC [C]

Synonym: VS_1382

Alternate gene names: 218709373

Gene position: 1496680-1498011 (Clockwise)

Preceding gene: 218709372

Following gene: 218709374

Centisome position: 45.36

GC content: 42.79

Gene sequence:

>1332_bases
ATGACCGTTCCCTTTACTGTTTTTGAATTTGGCTACTTAACTTGCGACGAACACGCTGCGCAAGCCAATGGTTACACGCT
TATTTCAGCCAATGCGTTTCAATATTTAGAGCGGCTTTGTTTAAATGAAAACAAAGGCAATGTAGGCCGTTTTTTAAAGC
TTTGCAGCCGATTCGGCGACAAGTTGCTGCAAGTAAGAAACTACGTGGGCGTATTGTTTACGCCCAATGGTGAACACGTT
GAAGTGTTACCCAAAGTAGCGAAAAAAACAGATAACTCAACAGAGGCCATCGACGAGTCGCGAAAACTCTTGCTGATGAT
GCTCAAACACCTTGGCGAATTTAGGCATATTGCCACTCAGTCGGCAAACGTTGATACCTTGAAAATGCCGCTGCTTGAAG
TGTTTATTCAGCAGTTTTTGCACAGTGTAAACCAACTGGTGAAGCGAGGTTTACGCAGTGACTACGTAAAACAGCAAGAC
AACTTAGGCTTTAAAAAAGGCAAGTTACTGGTGGCTAAACAGGTGCGCTATAACTCAGTGAACAAACACAAATTTTATTG
TGAGTTTGATGAGTTTTTGCAAAACAGACCAGCCAATCGGTTAATACGCGCCGCCTTAAAAAAAGTAGCGGTGTACACCC
GAAGGAACCAAAACCAAAGGTTACTTCGGGAGTTGGATTTTACGTTTGATGGCATACCTGCAAGTACCAATGTGAAGCAA
GATTTTGCGCGTGTAAAACTAGACAGAGGCATGGACTATTACCAGTCACCCCTTGCATGGGCAAGGTTAATCCTTGAAGG
GTTTTCACCTCTTAGTATGAAAGGTCAATCCAATGCTCAATCATTATTGTTCCCAATGGAGGCGGTCTTTGAAGGTTATG
TCGCGTCTATGCTACGCAGGAACTTAGCTGATGGTGTTACTCTTAGCTCGCAAGTTAAGTCTGAATATTTAGTTCACCAT
AATGGTCATCGCCAGTTCCAACTTCGTCCCGATTTAATGTTAACTAAGTCTGCCAAGTCGCCAGAAACGTGTGATACCAC
AGTGATTTTAGACACCAAATGGAAGTTGATTGATATCCAGGCAAAGAACTATGGCTTAGCTCAGTCAGACTTTTATCAAA
TGCTGGCATACGGGCAGAACTATCAAAGTGGTGTTGGTGACCTTGTTTTGATCTACCCACAGCATGAAGGGTTCGAAGAA
CCAATAGAGCACAGCTTTGAGTTCACTAAAGATCTTCGGTTATGGGTAGTACCATTTCAGATAGAACAGGATGGATTTAG
TCAATTAGTCACGAAGGAGTATCATCCGTTTCACAAGCTTATGAAGAGCTAA

Upstream 100 bases:

>100_bases
GATGAAGTGAAACGTGCCTTGTTGAAGGCTAATAATGACAATCAAGAACAAAGCGATAATACCGAAAATCAGCTGAGTTC
TGAGGGCGTGGTTGATTAAC

Downstream 100 bases:

>100_bases
GCCTCGTCTTTGTGAGTTAAGGTATTACTCATAACTTTAACAAGAATGAACCGCTAATGATTAGAGACAAACTACTCGAC
AGGCTTTTACTTGGATTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: 5-Methylcytosine Restriction System Component-Like Protein; McrBC 5-Methylcytosine Restriction System Component-Like; 5-Methylcytosine Restriction System Component; McrBC Catalytic Subunit McrC; McrBC Restriction Endonuclease System Subunit McrC; 5-Methylcytosine-Specific Restriction Protein C; McrBC 5-Methylcytosine Restriction Subunit McrC; 5-Methylcytosine Restriction System Component- Like Protein

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MTVPFTVFEFGYLTCDEHAAQANGYTLISANAFQYLERLCLNENKGNVGRFLKLCSRFGDKLLQVRNYVGVLFTPNGEHV
EVLPKVAKKTDNSTEAIDESRKLLLMMLKHLGEFRHIATQSANVDTLKMPLLEVFIQQFLHSVNQLVKRGLRSDYVKQQD
NLGFKKGKLLVAKQVRYNSVNKHKFYCEFDEFLQNRPANRLIRAALKKVAVYTRRNQNQRLLRELDFTFDGIPASTNVKQ
DFARVKLDRGMDYYQSPLAWARLILEGFSPLSMKGQSNAQSLLFPMEAVFEGYVASMLRRNLADGVTLSSQVKSEYLVHH
NGHRQFQLRPDLMLTKSAKSPETCDTTVILDTKWKLIDIQAKNYGLAQSDFYQMLAYGQNYQSGVGDLVLIYPQHEGFEE
PIEHSFEFTKDLRLWVVPFQIEQDGFSQLVTKEYHPFHKLMKS

Sequences:

>Translated_443_residues
MTVPFTVFEFGYLTCDEHAAQANGYTLISANAFQYLERLCLNENKGNVGRFLKLCSRFGDKLLQVRNYVGVLFTPNGEHV
EVLPKVAKKTDNSTEAIDESRKLLLMMLKHLGEFRHIATQSANVDTLKMPLLEVFIQQFLHSVNQLVKRGLRSDYVKQQD
NLGFKKGKLLVAKQVRYNSVNKHKFYCEFDEFLQNRPANRLIRAALKKVAVYTRRNQNQRLLRELDFTFDGIPASTNVKQ
DFARVKLDRGMDYYQSPLAWARLILEGFSPLSMKGQSNAQSLLFPMEAVFEGYVASMLRRNLADGVTLSSQVKSEYLVHH
NGHRQFQLRPDLMLTKSAKSPETCDTTVILDTKWKLIDIQAKNYGLAQSDFYQMLAYGQNYQSGVGDLVLIYPQHEGFEE
PIEHSFEFTKDLRLWVVPFQIEQDGFSQLVTKEYHPFHKLMKS
>Mature_442_residues
TVPFTVFEFGYLTCDEHAAQANGYTLISANAFQYLERLCLNENKGNVGRFLKLCSRFGDKLLQVRNYVGVLFTPNGEHVE
VLPKVAKKTDNSTEAIDESRKLLLMMLKHLGEFRHIATQSANVDTLKMPLLEVFIQQFLHSVNQLVKRGLRSDYVKQQDN
LGFKKGKLLVAKQVRYNSVNKHKFYCEFDEFLQNRPANRLIRAALKKVAVYTRRNQNQRLLRELDFTFDGIPASTNVKQD
FARVKLDRGMDYYQSPLAWARLILEGFSPLSMKGQSNAQSLLFPMEAVFEGYVASMLRRNLADGVTLSSQVKSEYLVHHN
GHRQFQLRPDLMLTKSAKSPETCDTTVILDTKWKLIDIQAKNYGLAQSDFYQMLAYGQNYQSGVGDLVLIYPQHEGFEEP
IEHSFEFTKDLRLWVVPFQIEQDGFSQLVTKEYHPFHKLMKS

Specific function: Modifies The Specificity Of Mcrb Restriction By Expanding The Range Of Modified Sequences Restricted. Does Not Bind To DNA. [C]

COG id: COG4268

COG function: function code V; McrBC 5-methylcytosine restriction system component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51067; Mature: 50936

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPFTVFEFGYLTCDEHAAQANGYTLISANAFQYLERLCLNENKGNVGRFLKLCSRFGD
CCCCEEEHHCCCEECCHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KLLQVRNYVGVLFTPNGEHVEVLPKVAKKTDNSTEAIDESRKLLLMMLKHLGEFRHIATQ
HHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SANVDTLKMPLLEVFIQQFLHSVNQLVKRGLRSDYVKQQDNLGFKKGKLLVAKQVRYNSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCC
NKHKFYCEFDEFLQNRPANRLIRAALKKVAVYTRRNQNQRLLRELDFTFDGIPASTNVKQ
CCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHH
DFARVKLDRGMDYYQSPLAWARLILEGFSPLSMKGQSNAQSLLFPMEAVFEGYVASMLRR
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLADGVTLSSQVKSEYLVHHNGHRQFQLRPDLMLTKSAKSPETCDTTVILDTKWKLIDIQ
HHHCCCEEHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCEEEEEECCEEEEEEE
AKNYGLAQSDFYQMLAYGQNYQSGVGDLVLIYPQHEGFEEPIEHSFEFTKDLRLWVVPFQ
ECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEE
IEQDGFSQLVTKEYHPFHKLMKS
ECCCHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TVPFTVFEFGYLTCDEHAAQANGYTLISANAFQYLERLCLNENKGNVGRFLKLCSRFGD
CCCEEEHHCCCEECCHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KLLQVRNYVGVLFTPNGEHVEVLPKVAKKTDNSTEAIDESRKLLLMMLKHLGEFRHIATQ
HHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SANVDTLKMPLLEVFIQQFLHSVNQLVKRGLRSDYVKQQDNLGFKKGKLLVAKQVRYNSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCC
NKHKFYCEFDEFLQNRPANRLIRAALKKVAVYTRRNQNQRLLRELDFTFDGIPASTNVKQ
CCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHH
DFARVKLDRGMDYYQSPLAWARLILEGFSPLSMKGQSNAQSLLFPMEAVFEGYVASMLRR
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLADGVTLSSQVKSEYLVHHNGHRQFQLRPDLMLTKSAKSPETCDTTVILDTKWKLIDIQ
HHHCCCEEHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCCCEEEEEECCEEEEEEE
AKNYGLAQSDFYQMLAYGQNYQSGVGDLVLIYPQHEGFEEPIEHSFEFTKDLRLWVVPFQ
ECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEE
IEQDGFSQLVTKEYHPFHKLMKS
ECCCHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA