Click here to switch to the map view.

The map label for this gene is 218709350

Identifier: 218709350

GI number: 218709350

Start: 1468643

End: 1470022

Strand: Direct

Name: 218709350

Synonym: VS_1359

Alternate gene names: NA

Gene position: 1468643-1470022 (Clockwise)

Preceding gene: 218709349

Following gene: 218709351

Centisome position: 44.51

GC content: 42.97

Gene sequence:

>1380_bases
GTGTTAAGGGAATGGCAAAGTGAATGCTCTGAAAGAGCGTTGAAAAAATATCAATCCAACGGCTCCCATTTCTTTTGCCA
AGCTACGCCAGGGGCTGGTAAGACAGTGCTTGCCGCTAATATTGCGTCAAGGCTGCTACAAAGTGACATGGCAGATCTTG
TATTGTGTTTCTCTCCATCATTGACGGTTTCTGATGGTATAAAAAGAACCTTTTCGTCGATACTTAATTGTACATTTAAT
GGTGGTATGGGAGCTATAGGGCAATCTTTAACATACCAATCTATCCAGTTCCTCAATGATGAGTTTTGGCAAATATTGCG
GAATCACAGGGTCTTTGTTGTCTTTGATGAAATACACCATTGCTCTGGCTCTGAGGTTGAAAATGCGAACATTTGGGGGC
AGCAAGTTCTCACAAAGATTCAAGGGCTTGCTACTTTTACCCTCGCACTTTCAGGTACACCGTGGCGTTCAGACTCTTTA
CCCATTGTGATGGGTGAGTACAGCGACCCAGACGGACAGCTTCTTGTCGATTACCAATACACTCTTAAACAAGCTATAGC
TGATGGTGTTTGTAGAACGCCCAAAATAGTCTTGGTTGATAATGAACATTTGTCGGTTAGTAGTAGCGAAAAAGTCGAAT
CCTTTTCATCCATATTAGAGATGCTTAAACAGACAAAAGCATCCTACCAGAGCGTTATTCACAACCAAGAGGCGATGGAA
TATCTACTCGGTTTAGGATGTGAGCGGCTAGAAAAAGTACGTCTCAGCTCACCTAATGCCGGTGGGCTGATTGTTGCAGC
GTCGGTTCAACATGCACAAACAATCAAAGAGATACTATCTCAAAAGTTTAGGCAAACCGTTTCTATTGTCACTTATCGAC
ATGAAGAGCCGCTAGCAGAAATAGGGCGTTATAGACAAAGCAACGCACAATGGATTGTTAGTGTAGGTATGATAAGTGAG
GGTACTGATATTCCGCGCCTTCAAGTATGTTGCCATATGAGTTCGGTCAAAACTGAATTGTATTTCAGGCAGGTGCTCGG
ACGAATACTTCGTGTGAATAATAAAATAAACCAACAAGCGTGGTTATTCACTTTTGCTGAACAAAGTCTGATTGAGTTTT
CTGACAGGATTGAACAGGATATTCCTGAGTCTCGTCTCTATGTAAGTATGGGGAAACCTATCGAAACAGAGTTCTCTGGT
CGAGGAAATAGCTTAAGTGTCGCGCTTCCGTTTAAGTCCCAAAACAGCGGGAGAACAACAGTATCTTGGGAAAGCAGTAC
AGACAGTTCAACTAGTCTCTATGGAACACTAGGGACGTTTGATGAGCTTCGACTTGGGGCATTTAAGCAGAGAGTGATCT
CGGCTTTCTCTTCCATGTAG

Upstream 100 bases:

>100_bases
CCCCTTTGCATCAGGAGGCTAAAGAACGCGCCGCTTTATTGCTAGGTAAAGTGAATGTTTTAACAAAGGTACTTAATACT
CTCTATGAAGGAGATGAACC

Downstream 100 bases:

>100_bases
TTGAAGAAACCGTAGGCTACAATAATTCACTAAAGCACATTGGAGATGTCGGAATGAACTACTTTGCAGAGGACCCCTTC
TAGGTAATGCAAACCTGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLREWQSECSERALKKYQSNGSHFFCQATPGAGKTVLAANIASRLLQSDMADLVLCFSPSLTVSDGIKRTFSSILNCTFN
GGMGAIGQSLTYQSIQFLNDEFWQILRNHRVFVVFDEIHHCSGSEVENANIWGQQVLTKIQGLATFTLALSGTPWRSDSL
PIVMGEYSDPDGQLLVDYQYTLKQAIADGVCRTPKIVLVDNEHLSVSSSEKVESFSSILEMLKQTKASYQSVIHNQEAME
YLLGLGCERLEKVRLSSPNAGGLIVAASVQHAQTIKEILSQKFRQTVSIVTYRHEEPLAEIGRYRQSNAQWIVSVGMISE
GTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNNKINQQAWLFTFAEQSLIEFSDRIEQDIPESRLYVSMGKPIETEFSG
RGNSLSVALPFKSQNSGRTTVSWESSTDSSTSLYGTLGTFDELRLGAFKQRVISAFSSM

Sequences:

>Translated_459_residues
MLREWQSECSERALKKYQSNGSHFFCQATPGAGKTVLAANIASRLLQSDMADLVLCFSPSLTVSDGIKRTFSSILNCTFN
GGMGAIGQSLTYQSIQFLNDEFWQILRNHRVFVVFDEIHHCSGSEVENANIWGQQVLTKIQGLATFTLALSGTPWRSDSL
PIVMGEYSDPDGQLLVDYQYTLKQAIADGVCRTPKIVLVDNEHLSVSSSEKVESFSSILEMLKQTKASYQSVIHNQEAME
YLLGLGCERLEKVRLSSPNAGGLIVAASVQHAQTIKEILSQKFRQTVSIVTYRHEEPLAEIGRYRQSNAQWIVSVGMISE
GTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNNKINQQAWLFTFAEQSLIEFSDRIEQDIPESRLYVSMGKPIETEFSG
RGNSLSVALPFKSQNSGRTTVSWESSTDSSTSLYGTLGTFDELRLGAFKQRVISAFSSM
>Mature_459_residues
MLREWQSECSERALKKYQSNGSHFFCQATPGAGKTVLAANIASRLLQSDMADLVLCFSPSLTVSDGIKRTFSSILNCTFN
GGMGAIGQSLTYQSIQFLNDEFWQILRNHRVFVVFDEIHHCSGSEVENANIWGQQVLTKIQGLATFTLALSGTPWRSDSL
PIVMGEYSDPDGQLLVDYQYTLKQAIADGVCRTPKIVLVDNEHLSVSSSEKVESFSSILEMLKQTKASYQSVIHNQEAME
YLLGLGCERLEKVRLSSPNAGGLIVAASVQHAQTIKEILSQKFRQTVSIVTYRHEEPLAEIGRYRQSNAQWIVSVGMISE
GTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNNKINQQAWLFTFAEQSLIEFSDRIEQDIPESRLYVSMGKPIETEFSG
RGNSLSVALPFKSQNSGRTTVSWESSTDSSTSLYGTLGTFDELRLGAFKQRVISAFSSM

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2917 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: NA

Molecular weight: Translated: 51205; Mature: 51205

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLREWQSECSERALKKYQSNGSHFFCQATPGAGKTVLAANIASRLLQSDMADLVLCFSPS
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCC
LTVSDGIKRTFSSILNCTFNGGMGAIGQSLTYQSIQFLNDEFWQILRNHRVFVVFDEIHH
CCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHC
CSGSEVENANIWGQQVLTKIQGLATFTLALSGTPWRSDSLPIVMGEYSDPDGQLLVDYQY
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEHHH
TLKQAIADGVCRTPKIVLVDNEHLSVSSSEKVESFSSILEMLKQTKASYQSVIHNQEAME
HHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YLLGLGCERLEKVRLSSPNAGGLIVAASVQHAQTIKEILSQKFRQTVSIVTYRHEEPLAE
HHHHCCHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHH
IGRYRQSNAQWIVSVGMISEGTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNNKINQQA
HHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WLFTFAEQSLIEFSDRIEQDIPESRLYVSMGKPIETEFSGRGNSLSVALPFKSQNSGRTT
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEE
VSWESSTDSSTSLYGTLGTFDELRLGAFKQRVISAFSSM
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLREWQSECSERALKKYQSNGSHFFCQATPGAGKTVLAANIASRLLQSDMADLVLCFSPS
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCC
LTVSDGIKRTFSSILNCTFNGGMGAIGQSLTYQSIQFLNDEFWQILRNHRVFVVFDEIHH
CCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHC
CSGSEVENANIWGQQVLTKIQGLATFTLALSGTPWRSDSLPIVMGEYSDPDGQLLVDYQY
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEHHH
TLKQAIADGVCRTPKIVLVDNEHLSVSSSEKVESFSSILEMLKQTKASYQSVIHNQEAME
HHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YLLGLGCERLEKVRLSSPNAGGLIVAASVQHAQTIKEILSQKFRQTVSIVTYRHEEPLAE
HHHHCCHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHH
IGRYRQSNAQWIVSVGMISEGTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNNKINQQA
HHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WLFTFAEQSLIEFSDRIEQDIPESRLYVSMGKPIETEFSGRGNSLSVALPFKSQNSGRTT
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEE
VSWESSTDSSTSLYGTLGTFDELRLGAFKQRVISAFSSM
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]