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The map label for this gene is dctB [H]

Identifier: 218709268

GI number: 218709268

Start: 1373439

End: 1374794

Strand: Direct

Name: dctB [H]

Synonym: VS_1275

Alternate gene names: 218709268

Gene position: 1373439-1374794 (Clockwise)

Preceding gene: 218709267

Following gene: 218709269

Centisome position: 41.63

GC content: 42.92

Gene sequence:

>1356_bases
GTGTATCAACAAAAGCTAGAAGCACTTATCGATCGTTATTTTAATCAGACAGAGCGTCGGGTGACGTGCCGTGCCGGTAA
CACCATTATTGAACAATCAGCGTTAAACACTCGTTTGTATTATGTGTTTAGTGGAGAACTGGAAGGGTTTTATTCCGAAG
CGAATACACCGCGAGTACGCGTGTTTAGCGCGGGTAGTGGAGCTTTTATAGGCGTTCATAGCTTCTTTTCAGGTAATTGG
ACAGCATCTTCAACGGTTGTTGCTAAAACCGATGTTGAGTTAGCGTGGATCGATAAAGACACGCCGGCAGAAGATGAACG
TAAATTTGGCCCTCTTACCGCACAGTTCACACCTGTGATTGTCAATGAGTTGTCGCGTCGTCAACGCCGTGCAACACAAG
AAGCGATCGCGAAACAAAAAGCGCTAGAGAAGTTACATACTGCTGAGCAAATGACGACCTTGGGTCAATTGGCTGCAGGG
ATTGCTCATGAGCTTAACAACGCTATTGGTGTAGTAAATAGTAAATCTGGCCGACTTGAAACGGTCATCATGGATCTACT
CGAAGAAGTGCATCCAGAAGCCAGTCAATTTTTCGATTTTGGGTTAATGCATGGTCAGAAAACGTCGTCGTCAGAAGCGC
GAACACGTGGGCGACAATTTGAAAGAAAATATGGTTTAGACAAAAACATTGCTCGCTCTCTTGCGAAGGCTATTCCAATT
GACGCTTCATCTGCAACAGACGTTATTTCAAAACATTGGCTGAAAAACCCAGAAGAAGCGATTCGCTTTTGGCAAATGGG
CTGTGATTTACATGATTTACGTTTGGCATCTAGACACACCGTTGGCATCGTAAAATCTGTTAAACAACTTGGCAGAGTTG
ATATTGACACCGAAGAAGCGGTTGATATTAATGACTCCATTAACCATGCATTATCGTTGTTACAAAGTGAGTTACGTAGA
GTATCTGTGCGATTGAGCCCTGCAGATTTGCCGACTTTTAAAGGCTCGAAAACAGAGCTCGTTCAGATTTGGGTCAACAT
TGTAAAGAATGCTTGTGATGCAATGTCGAATTCAGACGATGCTGCAATAGAAATTCAAACCAGATTAAGTAAGAAAAGAA
TATTAGTTACGATCACAAATAACGGCCCTGAGATAGACGAGGTGACTCGTAGAAAGGTATTTCAGCCCAACTTCACCACT
AAAAAAGGTGGTTTATCGTTTGGATTGGGCTTGGGTTTATCAATCGTTAAGCGGATTGTGGCGGGTTATGGCGGAAGCAT
CATTGTGAAAAGTGATGCTTCTAAAACTGTATTTAGAATCAAGTTACCAGTAGAGGGTGAACATGGAGAAGCTTAA

Upstream 100 bases:

>100_bases
AATGGCCAGAATCGGTATTATTTTAGGTGTGGTTGGTGTGCTACTGAGTTTTGTTATGGTGTGGGTGCTACATTCAATTG
GTCACATAGGATAACGATAC

Downstream 100 bases:

>100_bases
TTTAATCTGTGTCGATGACCAGAGAGAAGTACTGAGCGCAGTGGTACAAGATTTAGAGCCGCTGGCGAGTTGGCTGAATA
TTGAAGATTGTGAATCAGCG

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MYQQKLEALIDRYFNQTERRVTCRAGNTIIEQSALNTRLYYVFSGELEGFYSEANTPRVRVFSAGSGAFIGVHSFFSGNW
TASSTVVAKTDVELAWIDKDTPAEDERKFGPLTAQFTPVIVNELSRRQRRATQEAIAKQKALEKLHTAEQMTTLGQLAAG
IAHELNNAIGVVNSKSGRLETVIMDLLEEVHPEASQFFDFGLMHGQKTSSSEARTRGRQFERKYGLDKNIARSLAKAIPI
DASSATDVISKHWLKNPEEAIRFWQMGCDLHDLRLASRHTVGIVKSVKQLGRVDIDTEEAVDINDSINHALSLLQSELRR
VSVRLSPADLPTFKGSKTELVQIWVNIVKNACDAMSNSDDAAIEIQTRLSKKRILVTITNNGPEIDEVTRRKVFQPNFTT
KKGGLSFGLGLGLSIVKRIVAGYGGSIIVKSDASKTVFRIKLPVEGEHGEA

Sequences:

>Translated_451_residues
MYQQKLEALIDRYFNQTERRVTCRAGNTIIEQSALNTRLYYVFSGELEGFYSEANTPRVRVFSAGSGAFIGVHSFFSGNW
TASSTVVAKTDVELAWIDKDTPAEDERKFGPLTAQFTPVIVNELSRRQRRATQEAIAKQKALEKLHTAEQMTTLGQLAAG
IAHELNNAIGVVNSKSGRLETVIMDLLEEVHPEASQFFDFGLMHGQKTSSSEARTRGRQFERKYGLDKNIARSLAKAIPI
DASSATDVISKHWLKNPEEAIRFWQMGCDLHDLRLASRHTVGIVKSVKQLGRVDIDTEEAVDINDSINHALSLLQSELRR
VSVRLSPADLPTFKGSKTELVQIWVNIVKNACDAMSNSDDAAIEIQTRLSKKRILVTITNNGPEIDEVTRRKVFQPNFTT
KKGGLSFGLGLGLSIVKRIVAGYGGSIIVKSDASKTVFRIKLPVEGEHGEA
>Mature_451_residues
MYQQKLEALIDRYFNQTERRVTCRAGNTIIEQSALNTRLYYVFSGELEGFYSEANTPRVRVFSAGSGAFIGVHSFFSGNW
TASSTVVAKTDVELAWIDKDTPAEDERKFGPLTAQFTPVIVNELSRRQRRATQEAIAKQKALEKLHTAEQMTTLGQLAAG
IAHELNNAIGVVNSKSGRLETVIMDLLEEVHPEASQFFDFGLMHGQKTSSSEARTRGRQFERKYGLDKNIARSLAKAIPI
DASSATDVISKHWLKNPEEAIRFWQMGCDLHDLRLASRHTVGIVKSVKQLGRVDIDTEEAVDINDSINHALSLLQSELRR
VSVRLSPADLPTFKGSKTELVQIWVNIVKNACDAMSNSDDAAIEIQTRLSKKRILVTITNNGPEIDEVTRRKVFQPNFTT
KKGGLSFGLGLGLSIVKRIVAGYGGSIIVKSDASKTVFRIKLPVEGEHGEA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=150, Percent_Identity=32.6666666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50006; Mature: 50006

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQQKLEALIDRYFNQTERRVTCRAGNTIIEQSALNTRLYYVFSGELEGFYSEANTPRVR
CCHHHHHHHHHHHHCHHHHEEEEECCCHHHHHHCCCEEEEEEEECCCCHHHHCCCCCEEE
VFSAGSGAFIGVHSFFSGNWTASSTVVAKTDVELAWIDKDTPAEDERKFGPLTAQFTPVI
EEECCCCCEEEEEHHCCCCCCCCCEEEEECCEEEEEECCCCCCCHHHHCCCCCCCCHHHH
VNELSRRQRRATQEAIAKQKALEKLHTAEQMTTLGQLAAGIAHELNNAIGVVNSKSGRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
TVIMDLLEEVHPEASQFFDFGLMHGQKTSSSEARTRGRQFERKYGLDKNIARSLAKAIPI
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DASSATDVISKHWLKNPEEAIRFWQMGCDLHDLRLASRHTVGIVKSVKQLGRVDIDTEEA
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VDINDSINHALSLLQSELRRVSVRLSPADLPTFKGSKTELVQIWVNIVKNACDAMSNSDD
CCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AAIEIQTRLSKKRILVTITNNGPEIDEVTRRKVFQPNFTTKKGGLSFGLGLGLSIVKRIV
CEEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AGYGGSIIVKSDASKTVFRIKLPVEGEHGEA
HCCCCEEEEECCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MYQQKLEALIDRYFNQTERRVTCRAGNTIIEQSALNTRLYYVFSGELEGFYSEANTPRVR
CCHHHHHHHHHHHHCHHHHEEEEECCCHHHHHHCCCEEEEEEEECCCCHHHHCCCCCEEE
VFSAGSGAFIGVHSFFSGNWTASSTVVAKTDVELAWIDKDTPAEDERKFGPLTAQFTPVI
EEECCCCCEEEEEHHCCCCCCCCCEEEEECCEEEEEECCCCCCCHHHHCCCCCCCCHHHH
VNELSRRQRRATQEAIAKQKALEKLHTAEQMTTLGQLAAGIAHELNNAIGVVNSKSGRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
TVIMDLLEEVHPEASQFFDFGLMHGQKTSSSEARTRGRQFERKYGLDKNIARSLAKAIPI
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DASSATDVISKHWLKNPEEAIRFWQMGCDLHDLRLASRHTVGIVKSVKQLGRVDIDTEEA
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VDINDSINHALSLLQSELRRVSVRLSPADLPTFKGSKTELVQIWVNIVKNACDAMSNSDD
CCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AAIEIQTRLSKKRILVTITNNGPEIDEVTRRKVFQPNFTTKKGGLSFGLGLGLSIVKRIV
CEEEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AGYGGSIIVKSDASKTVFRIKLPVEGEHGEA
HCCCCEEEEECCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]